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G protein-coupled receptor kinases: more than just kinases and not only for GPCRs

Pharmacology & therapeutics (Oxford), 2012-01, Vol.133 (1), p.40-69

2012

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GPCRomics: An Approach to Discover GPCR Drug Targets

Trends in pharmacological sciences (Regular ed.), 2019-06, Vol.40 (6), p.378-387

2019

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Structural insights into G-protein-coupled receptor allostery

Nature (London), 2018-07, Vol.559 (7712), p.45-53

2018

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G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs)

The Journal of biological chemistry, 2015-04, Vol.290 (17), p.10775-10790

2015

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Free Fatty Acid Receptors and Drug Discovery

Biological and Pharmaceutical Bulletin, 2008/10/01, Vol.31(10), pp.1847-1851

2008

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Conformational Basis of G Protein-Coupled Receptor Signaling Versatility

Trends in cell biology, 2020-09, Vol.30 (9), p.736-747

2020

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G protein-coupled receptor kinases as therapeutic targets in the heart

Nature reviews cardiology, 2019-10, Vol.16 (10), p.612-622

2019

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Antagonistic Roles of GRK2 and GRK5 in Cardiac Aldosterone Signaling Reveal GRK5-Mediated Cardioprotection via Mineralocorticoid Receptor Inhibition

International journal of molecular sciences, 2020-04, Vol.21 (8), p.2868

2020

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Mechanisms of signalling and biased agonism in G protein-coupled receptors

Nature reviews. Molecular cell biology, 2018-10, Vol.19 (10), p.638-653

2018

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Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells

The Journal of biological chemistry, 2018-05, Vol.293 (19), p.7466-7473

2018

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Structure, function and pharmacology of human itch GPCRs

Nature (London), 2021-12, Vol.600 (7887), p.170-175

2021

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Structural basis of GPBAR activation and bile acid recognition

Nature (London), 2020-11, Vol.587 (7834), p.499-504

2020

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Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder

Neurobiology of disease, 2011-11, Vol.44 (2), p.248-258

2011

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Novel Allosteric Modulators of G Protein-coupled Receptors

The Journal of biological chemistry, 2015-08, Vol.290 (32), p.19478-19488

2015

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A dynamic and screening-compatible nanoluciferase-based complementation assay enables profiling of individual GPCR–G protein interactions

The Journal of biological chemistry, 2019-03, Vol.294 (11), p.4079-4090

2019

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PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Nature structural & molecular biology, 2015-05, Vol.22 (5), p.362-369

2015

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Illuminating G-Protein-Coupling Selectivity of GPCRs

Cell, 2019-06, Vol.177 (7), p.1933-1947.e25

2019

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Regulation of GPCR activity, trafficking and localization by GPCR‐interacting proteins

British journal of pharmacology, 2012-03, Vol.165 (6), p.1717-1736

2012

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Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

Nature (London), 2015-03, Vol.519 (7542), p.237-241

2015

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The expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development

Pharmacological research, 2016-08, Vol.110, p.52-64

2016

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Mechanisms of adhesion G protein–coupled receptor activation

The Journal of biological chemistry, 2020-10, Vol.295 (41), p.14065-14083

2020

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Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (19), p.8030-8035

2011

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G protein-coupled receptor kinases in normal and failing myocardium

Frontiers in bioscience, 2011-06, Vol.16 (8), p.3047-3060

2011

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Grk7 but not Grk1 undergoes cAMP-dependent phosphorylation in zebrafish cone photoreceptors and mediates cone photoresponse recovery to elevated cAMP

The Journal of biological chemistry, 2022-12, Vol.298 (12), p.102636-102636, Article 102636

2022

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Gα and regulator of G-protein signaling (RGS) protein pairs maintain functional compatibility and conserved interaction interfaces throughout evolution despite frequent loss of RGS proteins in plants

The New phytologist, 2017-10, Vol.216 (2), p.562-575

2017

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G protein-coupled receptor kinases: more than just kinases and not only for GPCRs

GPCRomics: An Approach to Discover GPCR Drug Targets

Structural insights into G-protein-coupled receptor allostery

G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs)

Free Fatty Acid Receptors and Drug Discovery

Conformational Basis of G Protein-Coupled Receptor Signaling Versatility

G protein-coupled receptor kinases as therapeutic targets in the heart

Antagonistic Roles of GRK2 and GRK5 in Cardiac Aldosterone Signaling Reveal GRK5-Mediated Cardioprotection via Mineralocorticoid Receptor Inhibition

Mechanisms of signalling and biased agonism in G protein-coupled receptors

Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells

Structure, function and pharmacology of human itch GPCRs

Structural basis of GPBAR activation and bile acid recognition

Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder

Novel Allosteric Modulators of G Protein-coupled Receptors

A dynamic and screening-compatible nanoluciferase-based complementation assay enables profiling of individual GPCR–G protein interactions

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Illuminating G-Protein-Coupling Selectivity of GPCRs

Regulation of GPCR activity, trafficking and localization by GPCR‐interacting proteins

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

The expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development

Mechanisms of adhesion G protein–coupled receptor activation

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

G protein-coupled receptor kinases in normal and failing myocardium

Grk7 but not Grk1 undergoes cAMP-dependent phosphorylation in zebrafish cone photoreceptors and mediates cone photoresponse recovery to elevated cAMP

Gα and regulator of G-protein signaling (RGS) protein pairs maintain functional compatibility and conserved interaction interfaces throughout evolution despite frequent loss of RGS proteins in plants

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