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Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics

Science (American Association for the Advancement of Science), 2012-04, Vol.336 (6079), p.315-319

2012

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Eukaryotic DNA Replication Fork

Annual review of biochemistry, 2017-06, Vol.86 (1), p.417-438

2017

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Symmetric activity of DNA polymerases at and recruitment of exonuclease ExoR and of PolA to the Bacillus subtilis replication forks

Nucleic acids research, 2019-09, Vol.47 (16), p.8521-8536

2019

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Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase

Nucleic acids research, 2016-11, Vol.44 (20), p.9530

2016

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Chromatin Constrains the Initiation and Elongation of DNA Replication

Molecular cell, 2017-01, Vol.65 (1), p.131-141

2017

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Roles of the Four DNA Polymerases of the Crenarchaeon Sulfolobus solfataricus and Accessory Proteins in DNA Replication

The Journal of biological chemistry, 2011-09, Vol.286 (36), p.31180-31193

2011

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DNA Polymerase Delta Synthesizes Both Strands during Break-Induced Replication

Molecular cell, 2019-11, Vol.76 (3), p.371-381.e4

2019

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The conserved RNP motif of the herpes simplex virus 1 family B DNA polymerase is crucial for viral DNA synthesis but not polymerase activity

Virology (New York, N.Y.), 2024-06, Vol.594, p.110035-110035, Article 110035

2024

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Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

Genome research, 2014-11, Vol.24 (11), p.1751-1764

2014

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DNA polymerase η contributes to genome-wide lagging strand synthesis

Nucleic acids research, 2019-03, Vol.47 (5), p.2425-2435

2019

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Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation

eLife, 2015-04, Vol.4, p.e04988-e04988

2015

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A conserved polar residue plays a critical role in mismatch detection in A-family DNA polymerases

International journal of biological macromolecules, 2024-06, Vol.269 (Pt 2), p.131965-131965, Article 131965

2024

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Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme

Nucleic acids research, 2020-04, Vol.48 (6), p.3165-3180

2020

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DNA Polymerase I Large Fragment from Deinococcus radiodurans , a Candidate for a Cutting-Edge Room-Temperature LAMP

International journal of molecular sciences, 2024-02, Vol.25 (3), p.1392

2024

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Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication

Molecular cell, 2020-01, Vol.77 (1), p.17-25.e5

2020

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Phylogenetic analyses of RPB1 and RPB2 support a middle Cretaceous origin for a clade comprising all agriculturally and medically important fusaria

Fungal genetics and biology, 2013-03, Vol.52, p.20-31

2013

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The mitochondrial DNA polymerase as a target of oxidative damage

Nucleic acids research, 2002-07, Vol.30 (13), p.2817-2824

2002

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Balancing eukaryotic replication asymmetry with replication fidelity

Current opinion in chemical biology, 2011-10, Vol.15 (5), p.620-626

Kunkel, Thomas A

2011

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Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases

Human molecular genetics, 2016-02, Vol.25 (4), p.715-727

2016

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CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells

Cancer research (Chicago, Ill.), 2020-04, Vol.80 (8), p.1735-1747

2020

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Role of DNA Polymerases in Repeat-Mediated Genome Instability

Cell reports (Cambridge), 2012-11, Vol.2 (5), p.1088-1095

2012

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Role of Accessory DNA Polymerases in DNA Replication in Escherichia coli: Analysis of the dnaX36 Mutator Mutant

Journal of Bacteriology, 2008-03, Vol.190 (5), p.1730-1742

2008

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Yeast model analysis of novel polymerase gamma variants found in patients with autosomal recessive mitochondrial disease

Human genetics, 2015-09, Vol.134 (9), p.951-966

2015

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MMS exposure promotes increased MtDNA mutagenesis in the presence of replication-defective disease-associated DNA polymerase γ variants

PLoS genetics, 2014-10, Vol.10 (10), p.e1004748

2014

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Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation

Journal of molecular biology, 2020-12, Vol.432 (24), p.166698-166698, Article 166698

2020

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Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics

Eukaryotic DNA Replication Fork

Symmetric activity of DNA polymerases at and recruitment of exonuclease ExoR and of PolA to the Bacillus subtilis replication forks

Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase

Chromatin Constrains the Initiation and Elongation of DNA Replication

Roles of the Four DNA Polymerases of the Crenarchaeon Sulfolobus solfataricus and Accessory Proteins in DNA Replication

DNA Polymerase Delta Synthesizes Both Strands during Break-Induced Replication

The conserved RNP motif of the herpes simplex virus 1 family B DNA polymerase is crucial for viral DNA synthesis but not polymerase activity

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

DNA polymerase η contributes to genome-wide lagging strand synthesis

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation

A conserved polar residue plays a critical role in mismatch detection in A-family DNA polymerases

Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme

DNA Polymerase I Large Fragment from Deinococcus radiodurans , a Candidate for a Cutting-Edge Room-Temperature LAMP

Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication

Phylogenetic analyses of RPB1 and RPB2 support a middle Cretaceous origin for a clade comprising all agriculturally and medically important fusaria

The mitochondrial DNA polymerase as a target of oxidative damage

Balancing eukaryotic replication asymmetry with replication fidelity

Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases

CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells

Role of DNA Polymerases in Repeat-Mediated Genome Instability

Role of Accessory DNA Polymerases in DNA Replication in Escherichia coli: Analysis of the dnaX36 Mutator Mutant

Yeast model analysis of novel polymerase gamma variants found in patients with autosomal recessive mitochondrial disease

MMS exposure promotes increased MtDNA mutagenesis in the presence of replication-defective disease-associated DNA polymerase γ variants

Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation

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