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Spatiotemporally Targeted Polypeptide Nanoantidotes Improve Chemotherapy Tolerance of Cisplatin

Angewandte Chemie International Edition, 2022-11, Vol.61 (47), p.e202211136-n/a

International ed. in English, 2022

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A Supramolecular Antidote to Macromolecular Toxins Prepared through Coassembly of Macrocyclic Amphiphiles

Advanced materials (Weinheim), 2021-10, Vol.33 (40), p.e2104310-n/a

2021

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Preferential Door for Ligand Binding and Unbinding Pathways in Inhibited Human Acetylcholinesterase

The journal of physical chemistry letters, 2024-05, Vol.15 (21), p.5696-5704

2024

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APOK3, a pollen killer antidote in Arabidopsis thaliana

Genetics (Austin), 2022-07, Vol.221 (4)

2022

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Location, Location, Location: an Antidote That Both Activates and Neutralizes a Toxin Used in Bacterial Warfare

Journal of bacteriology, 2023-06, Vol.205 (6), p.e0016123-e0016123

2023

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Nrf2 as a therapeutic target in acetaminophen hepatotoxicity: A case study with sulforaphane

Journal of biochemical and molecular toxicology, 2023-12, Vol.37 (12), p.e23505-e23505

2023

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Cisplatin Analogs Confer Protection against Cyanide Poisoning

Cell chemical biology, 2017-05, Vol.24 (5), p.565-575.e4

2017

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A Synthetic Gene Drive System for Local, Reversible Modification and Suppression of Insect Populations

Current biology, 2013-04, Vol.23 (8), p.671-677

2013

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Natural Products for the Prevention and Treatment of Hangover and Alcohol Use Disorder

Molecules, 2016-01, Vol.21 (1), p.64

2016

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A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

BMC pharmacology & toxicology, 2018-02, Vol.19 (1), p.8-10, Article 8

2018

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A high affinity, antidote‐controllable prothrombin and thrombin‐binding RNA aptamer inhibits thrombin generation and thrombin activity

Journal of thrombosis and haemostasis, 2012-05, Vol.10 (5), p.870-880

2012

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wtf genes are prolific dual poison-antidote meiotic drivers

eLife, 2017-06, Vol.6

2017

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NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction

Nature communications, 2016-04, Vol.7 (1), p.11361-11361, Article 11361

2016

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Carnitine in the treatment of valproic acid-induced toxicity

Clinical toxicology (Philadelphia, Pa.), 2009-02, Vol.47 (2), p.101-111

2009

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Zinc oxide nanoparticles provide anti-cholera activity by disrupting the interaction of cholera toxin with the human GM1 receptor

The Journal of biological chemistry, 2017-11, Vol.292 (44), p.18303-18311

2017

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Limitations in current acetylcholinesterase structure-based design of oxime antidotes for organophosphate poisoning

Annals of the New York Academy of Sciences, 2016-08, Vol.1378 (1), p.41-49

2016

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A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds

Toxicology letters, 2020-03, Vol.321, p.138-145

2020

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Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection

Toxicology letters, 2016-09, Vol.258, p.198-206

2016

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Intra-lineage microevolution of Wolbachia leads to the emergence of new cytoplasmic incompatibility patterns

PLoS biology, 2024-02, Vol.22 (2), p.e3002493-e3002493

2024

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The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs

Toxicology and applied pharmacology, 2021-03, Vol.415, p.115443, Article 115443

2021

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Complications Following Antidotal Use of Intravenous Lipid Emulsion Therapy

Journal of medical toxicology, 2014-03, Vol.10 (1), p.10-14

2014

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RNA aptamers as reversible antagonists of coagulation factor IXa

Nature (London), 2002-09, Vol.419 (6902), p.90-94

2002

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First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology : A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity

Circulation (New York, N.Y.), 2006-12, Vol.114 (23), p.2490-2497

2006

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Selenium as an antidote in the treatment of mercury intoxication

Biometals, 2015-08, Vol.28 (4), p.605-614

Bjoerklund, Geir

2015

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Pyridoxal oxime derivative potency to reactivate cholinesterases inhibited by organophosphorus compounds

Toxicology letters, 2016-11, Vol.262, p.114-122

2016

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Spatiotemporally Targeted Polypeptide Nanoantidotes Improve Chemotherapy Tolerance of Cisplatin

A Supramolecular Antidote to Macromolecular Toxins Prepared through Coassembly of Macrocyclic Amphiphiles

Preferential Door for Ligand Binding and Unbinding Pathways in Inhibited Human Acetylcholinesterase

APOK3, a pollen killer antidote in Arabidopsis thaliana

Location, Location, Location: an Antidote That Both Activates and Neutralizes a Toxin Used in Bacterial Warfare

Nrf2 as a therapeutic target in acetaminophen hepatotoxicity: A case study with sulforaphane

Cisplatin Analogs Confer Protection against Cyanide Poisoning

A Synthetic Gene Drive System for Local, Reversible Modification and Suppression of Insect Populations

Natural Products for the Prevention and Treatment of Hangover and Alcohol Use Disorder

A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

A high affinity, antidote‐controllable prothrombin and thrombin‐binding RNA aptamer inhibits thrombin generation and thrombin activity

wtf genes are prolific dual poison-antidote meiotic drivers

NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction

Carnitine in the treatment of valproic acid-induced toxicity

Zinc oxide nanoparticles provide anti-cholera activity by disrupting the interaction of cholera toxin with the human GM1 receptor

Limitations in current acetylcholinesterase structure-based design of oxime antidotes for organophosphate poisoning

A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds

Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection

Intra-lineage microevolution of Wolbachia leads to the emergence of new cytoplasmic incompatibility patterns

The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs

Complications Following Antidotal Use of Intravenous Lipid Emulsion Therapy

RNA aptamers as reversible antagonists of coagulation factor IXa

First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology : A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity

Selenium as an antidote in the treatment of mercury intoxication

Pyridoxal oxime derivative potency to reactivate cholinesterases inhibited by organophosphorus compounds

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