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Epigenome-wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis

Gastroenterology (New York, N.Y. 1943), 2017-10, Vol.153 (4), p.1096-1106.e2

2017

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Intracellular acidification reduces l-arginine transport via system y+L but not via system y+/CATs and nitric oxide synthase activity in human umbilical vein endothelial cells

Biochimica et biophysica acta. Molecular basis of disease, 2018-04, Vol.1864 (4), p.1192-1202

2018

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Several transport systems contribute to the intestinal uptake of Paraquat, modulating its cytotoxic effects

Toxicology letters, 2015-01, Vol.232 (1), p.271-283

2015

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Ferroptosis as a p53-mediated activity during tumour suppression

Nature (London), 2015-04, Vol.520 (7545), p.57-62

2015

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Mitochondrial regulation of ferroptosis

The Journal of cell biology, 2021-09, Vol.220 (9), p.1

Gan, Boyi

2021

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Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

Protein & cell, 2021-08, Vol.12 (8), p.599-620

2021

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Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Nature cell biology, 2020-04, Vol.22 (4), p.476-486

2020

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The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate

The Journal of biological chemistry, 2017-08, Vol.292 (34), p.14240-14249

2017

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Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma

The Journal of clinical investigation, 2020-04, Vol.130 (4), p.1752-1766

2020

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Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1

The Journal of biological chemistry, 2020-01, Vol.295 (1), p.69-82

2020

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Repression of the antiporter SLC7A11/glutathione/glutathione peroxidase 4 axis drives ferroptosis of vascular smooth muscle cells to facilitate vascular calcification

Kidney international, 2022-12, Vol.102 (6), p.1259-1275

2022

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The Chemistry and Biology of Ferroptosis

Cell chemical biology, 2020-04, Vol.27 (4), p.365-375

2020

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Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer

Cancer communications (London, England), 2018-04, Vol.38 (1), p.1-13

2018

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ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis

Journal of hepatology, 2023-08, Vol.79 (2), p.362-377

2023

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ATF3 promotes erastin-induced ferroptosis by suppressing system Xc

Cell death and differentiation, 2020-02, Vol.27 (2), p.662-675

2020

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BAP1 links metabolic regulation of ferroptosis to tumour suppression

Nature cell biology, 2018-10, Vol.20 (10), p.1181-1192

2018

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Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11

Cancer research (Chicago, Ill.), 2021-10, Vol.81 (20), p.5217-5229

2021

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Characterization of ferroptosis in kidney tubular cell death under diabetic conditions

Cell death & disease, 2021-02, Vol.12 (2), p.160-160, Article 160

2021

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Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1

Aging (Albany, NY.), 2020-06, Vol.12 (13), p.12943-12959

2020

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NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

Molecular cell, 2017-10, Vol.68 (1), p.224-232.e4

2017

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Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis

Cell metabolism, 2019-11, Vol.30 (5), p.877

2019

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Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer

Cancer letters, 2016-10, Vol.381 (1), p.96-103

2016

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The ASC-1 Complex Disassembles Collided Ribosomes

Molecular cell, 2020-08, Vol.79 (4), p.603-614.e8

2020

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Molecular basis for redox control by the human cystine/glutamate antiporter system xc

Nature communications, 2021-12, Vol.12 (1), p.7147-7147, Article 7147

2021

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Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53

EMBO reports, 2019-07, Vol.20 (7), p.e47563

2019

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Epigenome-wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis

Intracellular acidification reduces l-arginine transport via system y+L but not via system y+/CATs and nitric oxide synthase activity in human umbilical vein endothelial cells

Several transport systems contribute to the intestinal uptake of Paraquat, modulating its cytotoxic effects

Ferroptosis as a p53-mediated activity during tumour suppression

Mitochondrial regulation of ferroptosis

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate

Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma

Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1

Repression of the antiporter SLC7A11/glutathione/glutathione peroxidase 4 axis drives ferroptosis of vascular smooth muscle cells to facilitate vascular calcification

The Chemistry and Biology of Ferroptosis

Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer

ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc

BAP1 links metabolic regulation of ferroptosis to tumour suppression

Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11

Characterization of ferroptosis in kidney tubular cell death under diabetic conditions

Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1

NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis

Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer

The ASC-1 Complex Disassembles Collided Ribosomes

Molecular basis for redox control by the human cystine/glutamate antiporter system xc

Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53

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