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Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAαC) and 2-amino-9H-pyrido[2,3-b]indole (AαC) and identification of DNA adducts in organs from rats dosed with MeAαC

Carcinogenesis (New York), 2004-08, Vol.25 (8), p.1525-1533

2004

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Induction of CYP3A4 mRNA by cooked food-derived carcinogenic heterocyclic aromatic amines in human HPL-A3 cells

Fundamental toxicological sciences, 2022, Vol.9 (6), p.167-172

2022

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Effects of 2-amino-9H-pyrido[2,3-b]indole (AαC) metabolic bio-activation on oxidative DNA damage in human hepatoma G2 (HepG2) cells

Toxicology mechanisms and methods, 2018-03, Vol.28 (3), p.230-237

2018

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Physicochemical characterisation of dietary fibre components and their ability to bind some process-induced mutagenic heterocyclic amines, Trp-P-1, Trp-P-2, AαC and MeAαC

Food chemistry, 2013-06, Vol.138 (4), p.2219-2224

2013

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Genotoxic effects of dietary and lifestyle related carcinogens in human derived hepatoma (HepG2, Hep3B) cells

Mutation research, 2004-07, Vol.551 (1), p.153-166

2004

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Detoxification of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivative

Cancer letters, 1999-09, Vol.143 (2), p.167-171

1999

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Genotoxic and oxidative stress effects of 2-amino-9H-pyrido[2,3-b]indole in human hepatoma G2 (HepG2) and human lung alveolar epithelial (A549) cells

Toxicology mechanisms and methods, 2015-03, Vol.25 (3), p.212-222

2015

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Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains

Carcinogenesis (New York), 2003-12, Vol.24 (12), p.1913-1918

2003

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In-capillary micro solid-phase extraction and capillary electrophoresis separation of heterocyclic aromatic amines with nanospray mass spectrometric detection

Analytical and bioanalytical chemistry, 2004-04, Vol.378 (7), p.1729-1734

2004

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HETEROCYCLIC AROMATIC AMINE METABOLISM, DNA ADDUCT FORMATION, MUTAGENESIS, AND CARCINOGENESIS

Drug metabolism reviews, 2002-01, Vol.34 (3), p.625-650

Turesky, Robert J.

2002

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Heterocyclic aromatic amines induce DNA strand breaks and cell transformation

Carcinogenesis (New York), 1999-04, Vol.20 (4), p.545-551

1999

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Excretion of metabolites in urine and faeces from rats dosed with the heterocyclic amine, 2-amino-9 H-pyrido[2,3- b]indole (AαC)

Food and chemical toxicology, 2004, Vol.42 (6), p.879-885

2004

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Excretion of metabolites in urine and faeces from rats dosed with the heterocyclic amine, 2-amino-9H-pyrido[2,3-b]indole (AalphaC)

Food and chemical toxicology, 2004-06, Vol.42 (6), p.879-885

2004

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Mutagenic and carcinogenic heterocyclic amines as affected by muscle types/skin and cooking in pan-roasted mackerel

Mutation research, 2002-03, Vol.515 (1), p.189-195

2002

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The food mutagen 2-amino-9H-pyrido[2,3-b]indole (AαC) but not its methylated form (MeAαC) increases intestinal tumorigenesis in neonatally exposed multiple intestinal neoplasia mice

Carcinogenesis (New York), 2002-08, Vol.23 (8), p.1373-1378

2002

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Induction of aberrant crypt foci in C57BL/6N mice by 2-amino-9 H-pyrido [2,3- b]indole (AαC) and 2-amino-3,8-dimethylimidazo [4,5- f]quinoxaline (MeIQx)

Cancer letters, 1997, Vol.111 (1), p.105-109

1997

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Induction of aberrant crypt foci in C57BL/6N mice by 2-amino-9H-pyrido[2,3-b]indole (AαC) and 2-amino-3,8-dimethylimidazo [4,5-f]quinoxaline (MeIQw)

Cancer letters, 1997, Vol.111 (1-2), p.105-109

1997

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Effects of seasoning and heating device on mutagenicity and heterocyclic amines in cooked beef

Bioscience, biotechnology, and biochemistry, 2001-10, Vol.65 (10), p.2284-2287

2001

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In vitro bioactivation of N-hydroxy-2-amino-α-carboline

Carcinogenesis (New York), 2000-07, Vol.21 (7), p.1347-1354

2000

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Synthesis of mutagenic amino-.ALPHA.-carbolines A.ALPHA.C and MeA.ALPHA.C by the thermal electrocyclic reaction of 2-azahexa-1,3,5-triene intermediates

Chemical & pharmaceutical bulletin, 1991, Vol.39 (1), p.79-80

1991

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Synthesis of Mutagenic Amino-α-carbolines AαC and MeAαC by the Thermal Electrocyclic Reaction of 2-Azahexa-1, 3, 5-triene Intermediates

Chemical and Pharmaceutical Bulletin, 1991/01/25, Vol.39(1), pp.79-80

1991

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Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAαC) and 2-amino-9H-pyrido[2,3-b]indole (AαC) and identification of DNA adducts in organs from rats dosed with MeAαC

Induction of CYP3A4 mRNA by cooked food-derived carcinogenic heterocyclic aromatic amines in human HPL-A3 cells

Effects of 2-amino-9H-pyrido[2,3-b]indole (AαC) metabolic bio-activation on oxidative DNA damage in human hepatoma G2 (HepG2) cells

Physicochemical characterisation of dietary fibre components and their ability to bind some process-induced mutagenic heterocyclic amines, Trp-P-1, Trp-P-2, AαC and MeAαC

Genotoxic effects of dietary and lifestyle related carcinogens in human derived hepatoma (HepG2, Hep3B) cells

Detoxification of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivative

Genotoxic and oxidative stress effects of 2-amino-9H-pyrido[2,3-b]indole in human hepatoma G2 (HepG2) and human lung alveolar epithelial (A549) cells

Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains

In-capillary micro solid-phase extraction and capillary electrophoresis separation of heterocyclic aromatic amines with nanospray mass spectrometric detection

HETEROCYCLIC AROMATIC AMINE METABOLISM, DNA ADDUCT FORMATION, MUTAGENESIS, AND CARCINOGENESIS

Heterocyclic aromatic amines induce DNA strand breaks and cell transformation

Excretion of metabolites in urine and faeces from rats dosed with the heterocyclic amine, 2-amino-9 H-pyrido[2,3- b]indole (AαC)

Excretion of metabolites in urine and faeces from rats dosed with the heterocyclic amine, 2-amino-9H-pyrido[2,3-b]indole (AalphaC)

Mutagenic and carcinogenic heterocyclic amines as affected by muscle types/skin and cooking in pan-roasted mackerel

The food mutagen 2-amino-9H-pyrido[2,3-b]indole (AαC) but not its methylated form (MeAαC) increases intestinal tumorigenesis in neonatally exposed multiple intestinal neoplasia mice

Induction of aberrant crypt foci in C57BL/6N mice by 2-amino-9 H-pyrido [2,3- b]indole (AαC) and 2-amino-3,8-dimethylimidazo [4,5- f]quinoxaline (MeIQx)

Induction of aberrant crypt foci in C57BL/6N mice by 2-amino-9H-pyrido[2,3-b]indole (AαC) and 2-amino-3,8-dimethylimidazo [4,5-f]quinoxaline (MeIQw)

Effects of seasoning and heating device on mutagenicity and heterocyclic amines in cooked beef

In vitro bioactivation of N-hydroxy-2-amino-α-carboline

Synthesis of mutagenic amino-.ALPHA.-carbolines A.ALPHA.C and MeA.ALPHA.C by the thermal electrocyclic reaction of 2-azahexa-1,3,5-triene intermediates

Synthesis of Mutagenic Amino-α-carbolines AαC and MeAαC by the Thermal Electrocyclic Reaction of 2-Azahexa-1, 3, 5-triene Intermediates

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