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α‑Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment

Journal of medicinal chemistry, 2020-05, Vol.63 (9), p.4562-4578

2020

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Cyclosporine and COVID‐19: Risk or favorable?

American journal of transplantation, 2020-11, Vol.20 (11), p.2975-2982

2020

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Comprehensive Analysis of Varicella-Zoster Virus Proteins Using a New Monoclonal Antibody Collection

Journal of Virology, 2013-06, Vol.87 (12), p.6943-6954

2013

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The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation

The EMBO journal, 2021-06, Vol.40 (11), p.e102277-n/a

2021

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Structural characterization of the C-terminal domain of SARS-CoV-2 nucleocapsid protein

Molecular biomedicine, 2020-08, Vol.1 (1), p.2-2, Article 2

2020

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SARS-CoV-2 and Europe: timing of containment measures for outbreak control

Infection, 2020-06, Vol.48 (3), p.483-486

2020

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Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir

Virus research, 2014-05, Vol.184, p.44-53

2014

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Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506

Virus research, 2012-04, Vol.165 (1), p.112-117

2012

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A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

PLoS biology, 2021-12, Vol.19 (12), p.e3001490-e3001490

2021

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Tubulins interact with porcine and human S proteins of the genus Alphacoronavirus and support successful assembly and release of infectious viral particles

Virology (New York, N.Y.), 2016-10, Vol.497, p.185-197

2016

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Genetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication

Current opinion in virology, 2015-10, Vol.14, p.56-61

2015

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Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models

Frontiers in cellular and infection microbiology, 2022-09, Vol.12, p.958634-958634

2022

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Oxysterole-binding protein targeted by SARS-CoV-2 viral proteins regulates coronavirus replication

Frontiers in cellular and infection microbiology, 2024-07, Vol.14, p.1383917

2024

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Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome

PloS one, 2007-05, Vol.2 (5), p.e459-e459

2007

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Evolutionarily conserved herpesviral protein interaction networks

PLoS pathogens, 2009-09, Vol.5 (9), p.e1000570-e1000570

2009

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Cyclophilin A and CD147: novel therapeutic targets for the treatment of COVID-19

Medicine in drug discovery, 2020-09, Vol.7, p.100056-100056, Article 100056

2020

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Virus–host interactomes — antiviral drug discovery

Current opinion in virology, 2012-10, Vol.2 (5), p.614-621

2012

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Discrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs

Frontiers in medicine, 2021-11, Vol.8, p.749588-749588

2021

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Crystal structure of the middle domain of human poly(A)-binding protein-interacting protein 1

Biochemical and biophysical research communications, 2011-05, Vol.408 (4), p.680-685

2011

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Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication

Antiviral research, 2020-01, Vol.173, p.104620-104620, Article 104620

2020

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p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (35), p.E5192-E5201

2016

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Soluble uric acid inhibits β2 integrin–mediated neutrophil recruitment in innate immunity

Blood, 2022-06, Vol.139 (23), p.3402-3417

2022

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Automatische genetische Analytik

1, 1997

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The CoV-Y domain of SARS-CoV-2 Nsp3 interacts with BRAP to stimulate NF-κB signaling and induce host inflammatory responses

International journal of biological macromolecules, 2024-11, Vol.280 (Pt 4), p.136123, Article 136123

2024

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α‑Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment

Cyclosporine and COVID‐19: Risk or favorable?

Comprehensive Analysis of Varicella-Zoster Virus Proteins Using a New Monoclonal Antibody Collection

The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation

Structural characterization of the C-terminal domain of SARS-CoV-2 nucleocapsid protein

SARS-CoV-2 and Europe: timing of containment measures for outbreak control

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir

Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506

A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

Tubulins interact with porcine and human S proteins of the genus Alphacoronavirus and support successful assembly and release of infectious viral particles

Genetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication

Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models

Oxysterole-binding protein targeted by SARS-CoV-2 viral proteins regulates coronavirus replication

Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome

Evolutionarily conserved herpesviral protein interaction networks

Cyclophilin A and CD147: novel therapeutic targets for the treatment of COVID-19

Virus–host interactomes — antiviral drug discovery

Discrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs

Crystal structure of the middle domain of human poly(A)-binding protein-interacting protein 1

Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication

p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1

Soluble uric acid inhibits β2 integrin–mediated neutrophil recruitment in innate immunity

Automatische genetische Analytik

The CoV-Y domain of SARS-CoV-2 Nsp3 interacts with BRAP to stimulate NF-κB signaling and induce host inflammatory responses

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