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Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment

Pharmacology & therapeutics (Oxford), 2016-01, Vol.157, p.10-27

2016

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The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies

Psychopharmacology, 2015-01, Vol.232 (1), p.259-273

2015

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Hiding in plain sight: Do recruited dendritic cells surround amyloid plaques in alzheimer’s disease?

Biochemical pharmacology, 2024-05, p.116258-116258, Article 116258

2024

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Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139

Journal of medicinal chemistry, 2021-04, Vol.64 (8), p.4891-4902

2021

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P2X7 receptor‐mediated release of microglial prostanoids and miRNAs correlates with reversal of neuropathic hypersensitivity in rats

European journal of pain, 2022-07, Vol.26 (6), p.1304-1321

2022

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Inhibition of P2X7 receptors by Lu AF27139 diminishes colonic hypersensitivity and CNS prostanoid levels in a rat model of visceral pain

Purinergic signalling, 2022-12, Vol.18 (4), p.499-514

2022

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Preface: A Tribute to Paul Greengard (1925-2019)

A Tribute to Paul Greengard (1925-2019), 2021, Vol.90, p.xv-xix

Zorn, Stevin H

2021

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Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats

Neuropharmacology, 2014-08, Vol.83, p.28-35

2014

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Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profile

European journal of pharmacology, 2001-08, Vol.425 (3), p.197-201

2001

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5-HT1A receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex

Biological psychiatry (1969), 2000-08, Vol.48 (3), p.229-237

2000

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A Tribute to Paul Greengard (1925-2019)

Zorn, Stevin H

1, 2021

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Blockade of drug-induced deficits in prepulse inhibition of acoustic startle by ziprasidone

Pharmacology, biochemistry and behavior, 2001-07, Vol.69 (3), p.535-542

2001

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1-(2-Aminoethyl)-3-methyl-8,9-dihydropyrano[3,2-e]indole: a rotationally restricted phenolic analog of the neurotransmitter serotonin and agonist selective for serotonin (5-HT2-type) receptors

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3625-3632

1992

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3-Benzisothiazolylpiperazine Derivatives as Potential Atypical Antipsychotic Agents

Journal of medicinal chemistry, 1996-01, Vol.39 (1), p.143-148

1996

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The pharmacology of weight gain with antipsychotics

The journal of clinical psychiatry, 2001, Vol.62 Suppl 7, p.4

2001

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5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex

Biological psychiatry (1969), 2000-08, Vol.48 (3), p.229-237

2000

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The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine as a novel, nonpeptide substance P antagonist

Journal of medicinal chemistry, 1992-07, Vol.35 (14), p.2591-2600

1992

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The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-[HT.sub.1A] receptor signaling: mechanistic studies

Psychopharmacology, 2015-01, Vol.232 (1), p.259

2015

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The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT^sub 1A^ receptor signaling: mechanistic studies

Psychopharmacology, 2015-01, Vol.232 (1), p.259

2015

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The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT sub(1A) receptor signaling: mechanistic studies

Psychopharmacology, 2015-01, Vol.232 (1), p.259-273

2015

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The discovery of potent and selective dopamine D4 receptor antagonists

Current opinion in chemical biology, 1998-08, Vol.2 (4), p.535-540

1998

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Characterization in Mammalian Brain of a DARPP‐32 Serine Kinase Identical to Casein Kinase II

Journal of neurochemistry, 1990-11, Vol.55 (5), p.1772-1783

1990

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Cardiovascular effects of cholecystokinin-4 are mediated by the cholecystokinin-B receptor subtype in the conscious guinea pig and dog

The Journal of pharmacology and experimental therapeutics, 1997-04, Vol.281 (1), p.180

1997

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Comparison of the Novel Antipsychotic Ziprasidone with Clozapine and Olanzapine: Inhibition of Dorsal Raphe Cell Firing and the Role of 5-HT1A Receptor Activation

Neuropsychopharmacology (New York, N.Y.), 1999-11, Vol.21 (5), p.622-631

1999

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Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies

Hiding in plain sight: Do recruited dendritic cells surround amyloid plaques in alzheimer’s disease?

Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139

P2X7 receptor‐mediated release of microglial prostanoids and miRNAs correlates with reversal of neuropathic hypersensitivity in rats

Inhibition of P2X7 receptors by Lu AF27139 diminishes colonic hypersensitivity and CNS prostanoid levels in a rat model of visceral pain

Preface: A Tribute to Paul Greengard (1925-2019)

Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats

Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profile

5-HT1A receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex

A Tribute to Paul Greengard (1925-2019)

Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration

Blockade of drug-induced deficits in prepulse inhibition of acoustic startle by ziprasidone

1-(2-Aminoethyl)-3-methyl-8,9-dihydropyrano[3,2-e]indole: a rotationally restricted phenolic analog of the neurotransmitter serotonin and agonist selective for serotonin (5-HT2-type) receptors

3-Benzisothiazolylpiperazine Derivatives as Potential Atypical Antipsychotic Agents

The pharmacology of weight gain with antipsychotics

5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex

The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine as a novel, nonpeptide substance P antagonist

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-[HT.sub.1A] receptor signaling: mechanistic studies

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT^sub 1A^ receptor signaling: mechanistic studies

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT sub(1A) receptor signaling: mechanistic studies

The discovery of potent and selective dopamine D4 receptor antagonists

Characterization in Mammalian Brain of a DARPP‐32 Serine Kinase Identical to Casein Kinase II

Cardiovascular effects of cholecystokinin-4 are mediated by the cholecystokinin-B receptor subtype in the conscious guinea pig and dog

Comparison of the Novel Antipsychotic Ziprasidone with Clozapine and Olanzapine: Inhibition of Dorsal Raphe Cell Firing and the Role of 5-HT1A Receptor Activation

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