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The genetics of obesity: from discovery to biology

Nature reviews. Genetics, 2022-02, Vol.23 (2), p.120-133

2022

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The bigger picture of FTO: the first GWAS-identified obesity gene

Nature reviews. Endocrinology, 2014-01, Vol.10 (1), p.51-61

2014

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Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

Diabetologia, 2016-10, Vol.59 (10), p.2156-2165

2016

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Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

PloS one, 2010-01, Vol.5 (1), p.e8771-e8771

2010

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Unraveling the brain regulation of appetite: lessons from genetics

Nature neuroscience, 2012-10, Vol.15 (10), p.1343-1349

2012

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Metabolism in the spotlight: Dr. Giles Yeo on the impact and challenges of science communication

Cell, 2024-07, Vol.187 (15), p.3877-3879

Yeo, Giles S.H.

2024

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The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system

Biomaterials, 2014-04, Vol.35 (13), p.3919-3925

2014

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Adult onset global loss of the fto gene alters body composition and metabolism in the mouse

PLoS genetics, 2013-01, Vol.9 (1), p.e1003166-e1003166

2013

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Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Science (American Association for the Advancement of Science), 2007-11, Vol.318 (5855), p.1469-1472

2007

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Is calorie labelling on menus the solution to obesity?

Nature reviews. Endocrinology, 2022-08, Vol.18 (8), p.453-454

Yeo, Giles S H

2022

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Endoplasmic Reticulum Thiol Oxidase Deficiency Leads to Ascorbic Acid Depletion and Noncanonical Scurvy in Mice

Molecular cell, 2012-10, Vol.48 (1), p.39-51

2012

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PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism

PLoS genetics, 2007-04, Vol.3 (4), p.e64

2007

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Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort

Nature medicine, 2021-06, Vol.27 (6), p.1088-1096

2021

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Obesity and FTO: Changing Focus at a Complex Locus

Cell metabolism, 2014-11, Vol.20 (5), p.710-718

2014

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The biology of FTO: from nucleic acid demethylase to amino acid sensor

Diabetologia, 2013-10, Vol.56 (10), p.2113-2121

2013

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Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

American journal of human genetics, 2009-07, Vol.85 (1), p.106-111

2009

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Genetics of obesity: can an old dog teach us new tricks?

Diabetologia, 2017-05, Vol.60 (5), p.778-783

Yeo, Giles S. H.

2017

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Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene

Diabetes (New York, N.Y.), 2006-12, Vol.55 (12), p.3366-3371

2006

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High fat diet impairs the function of glucagon-like peptide-1 producing L-cells

Peptides (New York, N.Y. : 1980), 2016-03, Vol.77, p.21-27

2016

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Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling

Diabetes (New York, N.Y.), 2019-05, Vol.68 (5), p.1062-1072

2019

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Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome

The Journal of clinical investigation, 2018-03, Vol.128 (3), p.960-969

2018

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Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs

The Journal of neuroscience, 2010-11, Vol.30 (46), p.15464-15478

2010

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Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry

Endocrinology (Philadelphia), 2012-07, Vol.153 (7), p.3054-3065

2012

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The genetics of obesity: from discovery to biology

The bigger picture of FTO: the first GWAS-identified obesity gene

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

Unraveling the brain regulation of appetite: lessons from genetics

Metabolism in the spotlight: Dr. Giles Yeo on the impact and challenges of science communication

The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system

Adult onset global loss of the fto gene alters body composition and metabolism in the mouse

Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Is calorie labelling on menus the solution to obesity?

Endoplasmic Reticulum Thiol Oxidase Deficiency Leads to Ascorbic Acid Depletion and Noncanonical Scurvy in Mice

PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism

Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort

Obesity and FTO: Changing Focus at a Complex Locus

The biology of FTO: from nucleic acid demethylase to amino acid sensor

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

Genetics of obesity: can an old dog teach us new tricks?

Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene

GDF15 mediates the effects of metformin on body weight and energy balance

High fat diet impairs the function of glucagon-like peptide-1 producing L-cells

Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling

Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs

Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry

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