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Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease

Endocrinology (Philadelphia), 2015-12, Vol.156 (12), p.4592-4603

2015

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Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice

Neurobiology of aging, 2015-01, Vol.36 (1), p.334-343

2015

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Manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain after systemic administration of MnCl2: Hippocampal signal enhancement without disruption of hippocampus-dependent behavior

Behavioural brain research, 2011, Vol.216 (1), p.293-300

2011

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Diurnal and stress-induced intra-hippocampal corticosterone rise attenuated in 11β-HSD1-deficient mice: a microdialysis study in young and aged mice

The European journal of neuroscience, 2015-03, Vol.41 (6), p.787-792

2015

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Short-term inhibition of 11β-hydroxysteroid dehydrogenase type 1 reversibly improves spatial memory but persistently impairs contextual fear memory in aged mice

Neuropharmacology, 2015-04, Vol.91, p.71-76

2015

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Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

The European journal of neuroscience, 2007-03, Vol.25 (6), p.1832-1842

2007

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Inhibiting 11β-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning

Neuropharmacology, 2014-06, Vol.81, p.231-236

2014

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Local amplification of glucocorticoids in the aging brain and impaired spatial memory

Frontiers in aging neuroscience, 2012, Vol.4, p.24-24

2012

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Mining for Oxysterols in Cyp7b1 -/- Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5

Biomolecules (Basel, Switzerland), 2019-04, Vol.9 (4), p.149

2019

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Midlife stress alters memory and mood-related behaviors in old age: Role of locally activated glucocorticoids

Psychoneuroendocrinology, 2018-03, Vol.89, p.13-22

2018

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Chronic Treatment with the Antidepressant Amitriptyline Prevents Impairments in Water Maze Learning in Aging Rats

The Journal of neuroscience, 2002-02, Vol.22 (4), p.1436-1442

2002

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Central administration of a cytochrome P450-7B product 7 alpha-hydroxypregnenolone improves spatial memory retention in cognitively impaired aged rats

The Journal of neuroscience, 2006-10, Vol.26 (43), p.11034-11040

2006

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Cholestenoic acids regulate motor neuron survival via liver X receptors

The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4829-4842

2014

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24S,25-Epoxycholesterol in mouse and rat brain

Biochemical and biophysical research communications, 2014-06, Vol.449 (2), p.229-234

2014

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11β-Hydroxysteroid Dehydrogenase Type 1 Expression Is Increased in the Aged Mouse Hippocampus and Parietal Cortex and Causes Memory Impairments

The Journal of neuroscience, 2010-05, Vol.30 (20), p.6916-6920

2010

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11β-Hydroxysteroid Dehydrogenase Inhibition Improves Cognitive Function in Healthy Elderly Men and Type 2 Diabetics

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (17), p.6734-6739

2004

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The antidepressant desipramine requires the ABCBI (MdrI)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice

Neuropsychopharmacology (New York, N.Y.), 2007-12, Vol.32 (12), p.2520-2529

2007

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11β-Hydroxysteroid dehydrogenase 1 deficiency prevents PTSD-like memory in young adult mice

Psychoneuroendocrinology, 2022-12, Vol.146, p.105945, Article 105945

2022

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Lack of Tissue Glucocorticoid Reactivation in 11β-Hydroxysteroid Dehydrogenase Type 1 Knockout Mice Ameliorates Age-Related Learning Impairments

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (8), p.4716-4721

2001

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11β-Hydroxysteroid Dehydrogenase Type 1 Deficiency Prevents Memory Deficits with Aging by Switching from Glucocorticoid Receptor to Mineralocorticoid Receptor-Mediated Cognitive Control

The Journal of neuroscience, 2011-03, Vol.31 (11), p.4188-4193

2011

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Obese Zucker Rats Have Reduced Mineralocorticoid Receptor and 11β-Hydroxysteroid Dehydrogenase Type 1 Expression in Hippocampus—Implications for Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis in Obesity

Endocrinology (Philadelphia), 2003-07, Vol.144 (7), p.2997-3003

2003

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Partial Deficiency or Short-Term Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Improves Cognitive Function in Aging Mice

The Journal of neuroscience, 2010-10, Vol.30 (41), p.13867-13872

2010

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The effect of chronic fluoxetine treatment on brain corticosteroid receptor mRNA expression and spatial memory in young and aged rats

Brain research. Molecular brain research., 2002-10, Vol.106 (1), p.117-123

2002

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Enhanced Hippocampal Long-Term Potentiation and Spatial Learning in Aged 11β-Hydroxysteroid Dehydrogenase Type 1 Knock-Out Mice

The Journal of neuroscience, 2007-09, Vol.27 (39), p.10487-10496

2007

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Enhanced Hippocampal Long-Term Potentiation and Spatial Learning in Aged 11{beta}-Hydroxysteroid Dehydrogenase Type 1 Knock-Out Mice

The Journal of neuroscience, 2007-09, Vol.27 (39), p.10487-10496

2007

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Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease

Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice

Manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain after systemic administration of MnCl2: Hippocampal signal enhancement without disruption of hippocampus-dependent behavior

Diurnal and stress-induced intra-hippocampal corticosterone rise attenuated in 11β-HSD1-deficient mice: a microdialysis study in young and aged mice

Short-term inhibition of 11β-hydroxysteroid dehydrogenase type 1 reversibly improves spatial memory but persistently impairs contextual fear memory in aged mice

Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

Inhibiting 11β-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning

Local amplification of glucocorticoids in the aging brain and impaired spatial memory

Mining for Oxysterols in Cyp7b1 -/- Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5

Midlife stress alters memory and mood-related behaviors in old age: Role of locally activated glucocorticoids

Chronic Treatment with the Antidepressant Amitriptyline Prevents Impairments in Water Maze Learning in Aging Rats

Central administration of a cytochrome P450-7B product 7 alpha-hydroxypregnenolone improves spatial memory retention in cognitively impaired aged rats

Cholestenoic acids regulate motor neuron survival via liver X receptors

24S,25-Epoxycholesterol in mouse and rat brain

11β-Hydroxysteroid Dehydrogenase Type 1 Expression Is Increased in the Aged Mouse Hippocampus and Parietal Cortex and Causes Memory Impairments

11β-Hydroxysteroid Dehydrogenase Inhibition Improves Cognitive Function in Healthy Elderly Men and Type 2 Diabetics

The antidepressant desipramine requires the ABCBI (MdrI)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice

11β-Hydroxysteroid dehydrogenase 1 deficiency prevents PTSD-like memory in young adult mice

Lack of Tissue Glucocorticoid Reactivation in 11β-Hydroxysteroid Dehydrogenase Type 1 Knockout Mice Ameliorates Age-Related Learning Impairments

11β-Hydroxysteroid Dehydrogenase Type 1 Deficiency Prevents Memory Deficits with Aging by Switching from Glucocorticoid Receptor to Mineralocorticoid Receptor-Mediated Cognitive Control

Obese Zucker Rats Have Reduced Mineralocorticoid Receptor and 11β-Hydroxysteroid Dehydrogenase Type 1 Expression in Hippocampus—Implications for Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis in Obesity

Partial Deficiency or Short-Term Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Improves Cognitive Function in Aging Mice

The effect of chronic fluoxetine treatment on brain corticosteroid receptor mRNA expression and spatial memory in young and aged rats

Enhanced Hippocampal Long-Term Potentiation and Spatial Learning in Aged 11β-Hydroxysteroid Dehydrogenase Type 1 Knock-Out Mice

Enhanced Hippocampal Long-Term Potentiation and Spatial Learning in Aged 11{beta}-Hydroxysteroid Dehydrogenase Type 1 Knock-Out Mice

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