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Targeting Notch signaling pathway in cancer: Clinical development advances and challenges

Pharmacology & therapeutics (Oxford), 2014-02, Vol.141 (2), p.140-149

2014

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New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer

Cancer treatment reviews, 2016-04, Vol.45, p.87-96

2016

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Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

Nature reviews. Clinical oncology, 2015-08, Vol.12 (8), p.445-464

2015

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Systemic treatment and radiotherapy, breast cancer subtypes, and survival after long-term clinical follow-up

Breast cancer research and treatment, 2019-06, Vol.175 (2), p.287-295

2019

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Handbook of Therapeutic Biomarkers in Cancer

Second edition., 2021

Volltextzugriff (PDF)

DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors

Scientific reports, 2023-04, Vol.13 (1), p.5964-5964, Article 5964

2023

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Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancer

PloS one, 2011-10, Vol.6 (10), p.e25131-e25131

2011

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The VEGF Inhibitor Axitinib Has Limited Effectiveness as a Therapy for Adrenocortical Cancer

The journal of clinical endocrinology and metabolism, 2014-04, Vol.99 (4), p.1291-1297

2014

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Development and Validation of a Nomogram for Early Detection of Malignant Gallbladder Lesions

Clinical and translational gastroenterology, 2019-10, Vol.10 (10), p.e00098-e00098

2019

Volltextzugriff (PDF)

Antiangiogenic and Antitumor Effects of Bevacizumab in Patients With Inflammatory and Locally Advanced Breast Cancer

Journal of clinical oncology, 2006-02, Vol.24 (5), p.769-777

2006

Volltextzugriff (PDF)

Association of Independent Prognostic Factors and Treatment Modality With Survival and Recurrence Outcomes in Breast Cancer

JAMA network open, 2020-07, Vol.3 (7), p.e207213-e207213

2020

Volltextzugriff (PDF)

Locoregional tumor burden and risk of mortality in metastatic breast cancer

NPJ precision oncology, 2022-04, Vol.6 (1), p.22-22, Article 22

2022

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Pharmacokinetic and pharmacodynamic study of tariquidar (XR9576), a P-glycoprotein inhibitor, in combination with doxorubicin, vinorelbine, or docetaxel in children and adolescents with refractory solid tumors

Cancer chemotherapy and pharmacology, 2015-12, Vol.76 (6), p.1273-1283

2015

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Phase II Trial of Ixabepilone, an Epothilone B Analog, in Patients With Metastatic Breast Cancer Previously Untreated With Taxanes

Journal of clinical oncology, 2007-08, Vol.25 (23), p.3421-3427

2007

Volltextzugriff (PDF)

TET2 and DNMT3A mutations and exceptional response to 4′-thio-2′-deoxycytidine in human solid tumor models

Journal of hematology and oncology, 2021-05, Vol.14 (1), p.1-83, Article 83

2021

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Abstract 4722: Selective inhibition of DNA methyltransferases and efficacy of novel DNMT inhibitors in leukemia xenografts

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4722-4722

2016

Volltextzugriff (PDF)

Upregulation of TET2 and Resistance to DNA Methyltransferase (DNMT) Inhibitors in DNMT1-Deleted Cancer Cells

Diseases, 2024-07, Vol.12 (7), p.163

2024

Volltextzugriff (PDF)

Association of γH2AX at Diagnosis with Chemotherapy Outcome in Patients with Breast Cancer

Theranostics, 2017-01, Vol.7 (4), p.945-951

2017

Volltextzugriff (PDF)

Multiplexed Cell Signaling Analysis of Human Breast Cancer Applications for Personalized Therapy

Journal of proteome research, 2008-04, Vol.7 (4), p.1508-1517

2008

Volltextzugriff (PDF)

Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Metastatic and Locally Advanced Breast Cancer

Journal of clinical oncology, 2005-04, Vol.23 (12), p.2726-2734

2005

Volltextzugriff (PDF)

Akt Phosphorylation at Ser473 Predicts Benefit of Paclitaxel Chemotherapy in Node-Positive Breast Cancer

Journal of clinical oncology, 2010-06, Vol.28 (18), p.2974-2981

2010

Volltextzugriff (PDF)

Gene Expression Profile and Angiogenic Marker Correlates with Response to Neoadjuvant Bevacizumab Followed by Bevacizumab plus Chemotherapy in Breast Cancer

Clinical cancer research, 2008-09, Vol.14 (18), p.5893-5899

2008

Volltextzugriff (PDF)

Notch1 phenotype and clinical stage progression in non-small cell lung cancer

Journal of hematology and oncology, 2015-02, Vol.8 (1), p.9-9, Article 9

2015

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Designing Phase 0 Cancer Clinical Trials

Clinical cancer research, 2008-06, Vol.14 (12), p.3675-3682

2008

Volltextzugriff (PDF)

DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer

Molecular cancer therapeutics, 2012-02, Vol.11 (2), p.370-382

2012

Volltextzugriff (PDF)

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Targeting Notch signaling pathway in cancer: Clinical development advances and challenges

New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

Systemic treatment and radiotherapy, breast cancer subtypes, and survival after long-term clinical follow-up

Handbook of Therapeutic Biomarkers in Cancer

DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors

Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancer

The VEGF Inhibitor Axitinib Has Limited Effectiveness as a Therapy for Adrenocortical Cancer

Development and Validation of a Nomogram for Early Detection of Malignant Gallbladder Lesions

Antiangiogenic and Antitumor Effects of Bevacizumab in Patients With Inflammatory and Locally Advanced Breast Cancer

Association of Independent Prognostic Factors and Treatment Modality With Survival and Recurrence Outcomes in Breast Cancer

Locoregional tumor burden and risk of mortality in metastatic breast cancer

Pharmacokinetic and pharmacodynamic study of tariquidar (XR9576), a P-glycoprotein inhibitor, in combination with doxorubicin, vinorelbine, or docetaxel in children and adolescents with refractory solid tumors

Phase II Trial of Ixabepilone, an Epothilone B Analog, in Patients With Metastatic Breast Cancer Previously Untreated With Taxanes

TET2 and DNMT3A mutations and exceptional response to 4′-thio-2′-deoxycytidine in human solid tumor models

Abstract 4722: Selective inhibition of DNA methyltransferases and efficacy of novel DNMT inhibitors in leukemia xenografts

Upregulation of TET2 and Resistance to DNA Methyltransferase (DNMT) Inhibitors in DNMT1-Deleted Cancer Cells

Association of γH2AX at Diagnosis with Chemotherapy Outcome in Patients with Breast Cancer

Multiplexed Cell Signaling Analysis of Human Breast Cancer Applications for Personalized Therapy

Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Metastatic and Locally Advanced Breast Cancer

Akt Phosphorylation at Ser473 Predicts Benefit of Paclitaxel Chemotherapy in Node-Positive Breast Cancer

Gene Expression Profile and Angiogenic Marker Correlates with Response to Neoadjuvant Bevacizumab Followed by Bevacizumab plus Chemotherapy in Breast Cancer

Notch1 phenotype and clinical stage progression in non-small cell lung cancer

Designing Phase 0 Cancer Clinical Trials

DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer

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