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Mechanism of Dissolution-Induced Nanoparticle Formation from a Copovidone-Based Amorphous Solid Dispersion

Molecular pharmaceutics, 2016-05, Vol.13 (5), p.1467-1481

2016

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Base-Mediated Oxidative Degradation of Secondary Amides Derived from p-Amino Phenol to Primary Amides in Drug Molecules

Journal of pharmaceutical sciences, 2020-11, Vol.109 (11), p.3394-3403

2020

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Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1685-1694

2022

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Investigation of orexin-2 selective receptor antagonists: Structural modifications resulting in dual orexin receptor antagonists

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (6), p.1364-1370

2017

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Accelerated Forced Degradation of Pharmaceuticals in Levitated Microdroplet Reactors

Chemistry : a European journal, 2018-05, Vol.24 (29), p.7349-7353

2018

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Development of an ultra‐high‐performance liquid chromatography‐charged aerosol detection/UV method for the quantitation of linear polyethylenimines in oligonucleotide polyplexes

Journal of separation science, 2020-10, Vol.43 (20), p.3876-3884

2020

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Assessing the Impact of Different Light Sources on Product Quality During Pharmaceutical Drug Product Manufacture – Fluorescent Versus Light-Emitting Diode Light

Journal of pharmaceutical sciences, 2020-11, Vol.109 (11), p.3360-3369

2020

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Mechanistic understanding of abnormal reverse phase chromatographic behavior of basic analytes in the presence of sodium dodecyl sulfate

Journal of Chromatography A, 2019-06, Vol.1595, p.108-116

2019

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Polysorbate 80 UV/vis spectral and chromatographic characteristics – defining boundary conditions for use of the surfactant in dissolution analysis

Journal of pharmaceutical and biomedical analysis, 2006-06, Vol.41 (3), p.774-782

2006

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Detection and quantification of low-molecular-weight aldehydes in pharmaceutical excipients by headspace gas chromatography

Journal of Chromatography A, 2006-02, Vol.1104 (1), p.1-10

2006

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Molecular Mechanism of P53 Peptide Permeation through Lipid Membranes from Solid-State NMR Spectroscopy and Molecular Dynamics Simulations

Journal of the American Chemical Society, 2024-08, Vol.146 (33), p.23075-23091

2024

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Probing Protein Conformation Destabilization in Sterile Liquid Formulations through the Formation of 3,4-Dihydroxyphenylalanine

Molecular pharmaceutics, 2020-10, Vol.17 (10), p.3783-3793

2020

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Enrichment of Relevant Oxidative Degradation Products in Pharmaceuticals With Targeted Chemoselective Oxidation

Journal of pharmaceutical sciences, 2019-04, Vol.108 (4), p.1466-1475

2019

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Electron Hopping through Films of Arenethiolate Monolayer-Protected Gold Clusters

The journal of physical chemistry. B, 2002-03, Vol.106 (12), p.3139-3145

2002

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Electronic Conductivity of Solid-State, Mixed-Valent, Monolayer-Protected Au Clusters

Journal of the American Chemical Society, 2000-11, Vol.122 (46), p.11465-11472

2000

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Nanometer Gold Clusters Protected by Surface-Bound Monolayers of Thiolated Poly(ethylene glycol) Polymer Electrolyte

Journal of the American Chemical Society, 1998-12, Vol.120 (48), p.12696-12697

1998

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In-Use Photostability Practice and Regulatory Evaluation for Pharmaceutical Products in an Age of Light-Emitting Diode Light Sources

Journal of pharmaceutical sciences, 2019-03, Vol.108 (3), p.1172-1176

2019

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Preclinical Dose Number and Its Application in Understanding Drug Absorption Risk and Formulation Design for Preclinical Species

Molecular pharmaceutics, 2015-04, Vol.12 (4), p.1031-1039

2015

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Development of an automated and High throughput UHPLC/MS based workflow for cleaning verification of potent compounds in the pharmaceutical manufacturing environment

Journal of pharmaceutical and biomedical analysis, 2020-09, Vol.188, p.113401-113401, Article 113401

2020

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Probing in Vitro Release Kinetics of Long-Acting Injectable Nanosuspensions via Flow-NMR Spectroscopy

Molecular pharmaceutics, 2020-02, Vol.17 (2), p.530-540, Article acs.molpharmaceut.9b00958

2020

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Iron(III)-Mediated Oxidative Degradation on the Benzylic Carbon of Drug Molecules in the Absence of Initiating Peroxides

Journal of pharmaceutical sciences, 2017-05, Vol.106 (5), p.1347-1354

2017

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Identification of Suitable Formulations for High Dose Oral Studies in Rats Using In Vitro Solubility Measurements, the Maximum Absorbable Dose Model, and Historical Data Sets

Molecular pharmaceutics, 2012-05, Vol.9 (5), p.1163-1174

2012

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Mixed Reality Meets Pharmaceutical Development

Journal of pharmaceutical sciences, 2017-12, Vol.106 (12), p.3438-3441

2017

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Taylor Dispersion Measurements of Monolayer Protected Clusters: A Physicochemical Determination of Nanoparticle Size

Analytical chemistry (Washington), 1999-09, Vol.71 (18), p.4069-4074

1999

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Profiling of medium chain glycerides used in pharmaceutical formulation development by reversed-phase HPLC

Journal of pharmaceutical and biomedical analysis, 2006-03, Vol.40 (4), p.896-900

2006

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Mechanism of Dissolution-Induced Nanoparticle Formation from a Copovidone-Based Amorphous Solid Dispersion

Base-Mediated Oxidative Degradation of Secondary Amides Derived from p-Amino Phenol to Primary Amides in Drug Molecules

Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery

Investigation of orexin-2 selective receptor antagonists: Structural modifications resulting in dual orexin receptor antagonists

Accelerated Forced Degradation of Pharmaceuticals in Levitated Microdroplet Reactors

Development of an ultra‐high‐performance liquid chromatography‐charged aerosol detection/UV method for the quantitation of linear polyethylenimines in oligonucleotide polyplexes

Assessing the Impact of Different Light Sources on Product Quality During Pharmaceutical Drug Product Manufacture – Fluorescent Versus Light-Emitting Diode Light

Mechanistic understanding of abnormal reverse phase chromatographic behavior of basic analytes in the presence of sodium dodecyl sulfate

Polysorbate 80 UV/vis spectral and chromatographic characteristics – defining boundary conditions for use of the surfactant in dissolution analysis

Detection and quantification of low-molecular-weight aldehydes in pharmaceutical excipients by headspace gas chromatography

Molecular Mechanism of P53 Peptide Permeation through Lipid Membranes from Solid-State NMR Spectroscopy and Molecular Dynamics Simulations

Probing Protein Conformation Destabilization in Sterile Liquid Formulations through the Formation of 3,4-Dihydroxyphenylalanine

Enrichment of Relevant Oxidative Degradation Products in Pharmaceuticals With Targeted Chemoselective Oxidation

Electron Hopping through Films of Arenethiolate Monolayer-Protected Gold Clusters

Electronic Conductivity of Solid-State, Mixed-Valent, Monolayer-Protected Au Clusters

Nanometer Gold Clusters Protected by Surface-Bound Monolayers of Thiolated Poly(ethylene glycol) Polymer Electrolyte

In-Use Photostability Practice and Regulatory Evaluation for Pharmaceutical Products in an Age of Light-Emitting Diode Light Sources

Preclinical Dose Number and Its Application in Understanding Drug Absorption Risk and Formulation Design for Preclinical Species

Development of an automated and High throughput UHPLC/MS based workflow for cleaning verification of potent compounds in the pharmaceutical manufacturing environment

Probing in Vitro Release Kinetics of Long-Acting Injectable Nanosuspensions via Flow-NMR Spectroscopy

Iron(III)-Mediated Oxidative Degradation on the Benzylic Carbon of Drug Molecules in the Absence of Initiating Peroxides

Identification of Suitable Formulations for High Dose Oral Studies in Rats Using In Vitro Solubility Measurements, the Maximum Absorbable Dose Model, and Historical Data Sets

Mixed Reality Meets Pharmaceutical Development

Taylor Dispersion Measurements of Monolayer Protected Clusters: A Physicochemical Determination of Nanoparticle Size

Profiling of medium chain glycerides used in pharmaceutical formulation development by reversed-phase HPLC

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