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Hypoxia signalling through mTOR and the unfolded protein response in cancer

Nature reviews. Cancer, 2008-11, Vol.8 (11), p.851-864

2008

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Molecular targeting of hypoxia in radiotherapy

Advanced drug delivery reviews, 2017-01, Vol.109, p.45-62

2017

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Hypoxia-activated prodrugs: paths forward in the era of personalised medicine

British journal of cancer, 2016-05, Vol.114 (10), p.1071-1077

2016

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Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response

Breast cancer research : BCR, 2013-01, Vol.15 (1), p.R2-R2, Article R2

2013

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NanoStringNorm: an extensible R package for the pre-processing of NanoString mRNA and miRNA data

Bioinformatics (Oxford, England), 2012-06, Vol.28 (11), p.1546-1548

2012

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A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients

Nature materials, 2016-02, Vol.15 (2), p.227-234

2016

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The Roles of Reactive Oxygen Species and Autophagy in Mediating the Tolerance of Tumor Cells to Cycling Hypoxia

Seminars in radiation oncology, 2013-10, Vol.23 (4), p.252-261

2013

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PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (12), p.4622-4627

2013

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

The Journal of clinical investigation, 2010-01, Vol.120 (1), p.127-141

2010

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“Translating” Tumor Hypoxia: Unfolded Protein Response (UPR)–Dependent and UPR-Independent Pathways

Molecular cancer research, 2006-07, Vol.4 (7), p.423-436

2006

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Tellurophene‐Tagging of Teniposide Facilitates Monitoring by Mass Cytometry

Chembiochem : a European journal of chemical biology, 2022-10, Vol.23 (20), p.e202200284-n/a

2022

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The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress

Nature (London), 2014-06, Vol.510 (7504), p.268-272

2014

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Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

Nature communications, 2014-10, Vol.5 (1), Article 5203

2014

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MATE2 Expression Is Associated with Cancer Cell Response to Metformin

PloS one, 2016-12, Vol.11 (12), p.e0165214

2016

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Two phases of disulfide bond formation have differing requirements for oxygen

The Journal of cell biology, 2013-11, Vol.203 (4), p.615-627

2013

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Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response

Clinical cancer research, 2013-12, Vol.19 (24), p.6741-6750

2013

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Regulation of autophagy through multiple independent hypoxic signaling pathways

Current molecular medicine, 2009-05, Vol.9 (4), p.417-424

2009

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De Novo Design and Development of a Nutrient-Rich Perfusate for Ex Vivo Lung Perfusion with Cell Culture Models

International journal of molecular sciences, 2023-09, Vol.24 (17), p.13117

2023

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Hypoxia and Predicting Radiation Response

Seminars in radiation oncology, 2015-10, Vol.25 (4), p.260-272

2015

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Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

Nature communications, 2014-10, Vol.5, p.5203-5203

2014

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Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis

Journal of the American College of Cardiology, 2008-04, Vol.51 (13), p.1258-1265

2008

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Exploring the single-cell immune landscape of kidney allograft inflammation using imaging mass cytometry

American journal of transplantation, 2024-04, Vol.24 (4), p.549-563

2024

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Targeting Hypoxia-Inducible Factors for Antiangiogenic Cancer Therapy

Trends in Cancer, 2017-07, Vol.3 (7), p.529-541

2017

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

The EMBO journal, 2005-10, Vol.24 (19), p.3470-3481

2005

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PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

Nature cell biology, 2016-07, Vol.18 (7), p.803-813

2016

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Hypoxia signalling through mTOR and the unfolded protein response in cancer

Molecular targeting of hypoxia in radiotherapy

Hypoxia-activated prodrugs: paths forward in the era of personalised medicine

Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response

NanoStringNorm: an extensible R package for the pre-processing of NanoString mRNA and miRNA data

A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients

The Roles of Reactive Oxygen Species and Autophagy in Mediating the Tolerance of Tumor Cells to Cycling Hypoxia

PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

“Translating” Tumor Hypoxia: Unfolded Protein Response (UPR)–Dependent and UPR-Independent Pathways

Tellurophene‐Tagging of Teniposide Facilitates Monitoring by Mass Cytometry

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

MATE2 Expression Is Associated with Cancer Cell Response to Metformin

Two phases of disulfide bond formation have differing requirements for oxygen

Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response

Regulation of autophagy through multiple independent hypoxic signaling pathways

De Novo Design and Development of a Nutrient-Rich Perfusate for Ex Vivo Lung Perfusion with Cell Culture Models

Hypoxia and Predicting Radiation Response

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis

Exploring the single-cell immune landscape of kidney allograft inflammation using imaging mass cytometry

Targeting Hypoxia-Inducible Factors for Antiangiogenic Cancer Therapy

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

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