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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

Journal of biochemistry (Tokyo), 2015-06, Vol.157 (6), p.485-495

2015

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Impaired inflammatory responses in murine Lrrk2-knockdown brain microglia

PloS one, 2012-04, Vol.7 (4), p.e34693-e34693

2012

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Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model

Neurobiology of disease, 2021-07, Vol.154, p.105349, Article 105349

2021

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Effects of antidepressant drugs on synaptic protein levels and dendritic outgrowth in hippocampal neuronal cultures

Neuropharmacology, 2014-04, Vol.79, p.222-233

2014

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LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss

Cells (Basel, Switzerland), 2022-03, Vol.11 (5), p.861

2022

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p11 mediates the BDNF-protective effects in dendritic outgrowth and spine formation in B27-deprived primary hippocampal cells

Journal of affective disorders, 2016-05, Vol.196, p.1-10

2016

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LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death

Biochimica et biophysica acta. Molecular cell research, 2017-12, Vol.1864 (12), p.2356-2368

2017

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G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

BioMed research international, 2016-01, Vol.2016 (2016), p.1-8

2016

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Bi-directional regulation of AIMP2 and its splice variant on PARP-1-dependent neuronal cell death; Therapeutic implication for Parkinson's disease

Acta neuropathologica communications, 2024-01, Vol.12 (1), p.5-5, Article 5

2024

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G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

Animal Cells and Systems, 2019, 23(2), , pp.106-111

2019

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Astrocytes in injury states rapidly produce anti‐inflammatory factors and attenuate microglial inflammatory responses

Journal of neurochemistry, 2010-12, Vol.115 (5), p.1161-1171

2010

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Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

Parkinson's disease, 2018-01, Vol.2018 (2018), p.1-9

2018

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Effect of leucine-rich repeat kinase 2 (LRRK2) on protein synthesis

Animal Cells and Systems, 2018, 22(1), , pp.15-21

2018

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Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease

Animal Cells and Systems, 2021, 25(1), , pp.28-36

2021

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Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1β-Mediated Inflammatory Signaling through Phosphorylation of RCAN1

Frontiers in cellular neuroscience, 2017-05, Vol.11, p.125-125

2017

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Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein

Cell cycle (Georgetown, Tex.), 2019-02, Vol.18 (4), p.467-475

2019

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Androstane metabolites bind to and deactivate the nuclear receptor CAR-β

Nature (London), 1998-10, Vol.395 (6702), p.612-615

1998

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Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Animal Cells and Systems, 2018, 22(5), , pp.273-280

2018

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Leucine-rich Repeat Kinase 2 (LRRK2) Phosphorylates Rab10 in Glia and Neurons

Biomedical Science Letters, 2019-06, Vol.25 (2), p.177-184

2019

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Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Molecular brain, 2017-10, Vol.10 (1), p.48-48, Article 48

2017

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Human zinc fingers as building blocks in the construction of artificial transcription factors

Nature biotechnology, 2003-03, Vol.21 (3), p.275-280

2003

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Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors

Nature biotechnology, 2003-10, Vol.21 (10), p.1208-1214

2003

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Characterization of Parkinson's disease-related pathogenic TMEM230 mutants

Animal Cells and Systems, 2018, 22(2), , pp.140-147

2018

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Regulation of the transcriptional activity of the tyrosine hydroxylase gene by androgen receptor

Neuroscience letters, 2006-03, Vol.396 (1), p.57-61

2006

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A Cofactor of tRNA Synthetase, p43, Is Secreted to Up-regulate Proinflammatory Genes

The Journal of biological chemistry, 2001-06, Vol.276 (25), p.23028-23033

2001

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An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

Impaired inflammatory responses in murine Lrrk2-knockdown brain microglia

Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model

Effects of antidepressant drugs on synaptic protein levels and dendritic outgrowth in hippocampal neuronal cultures

LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss

p11 mediates the BDNF-protective effects in dendritic outgrowth and spine formation in B27-deprived primary hippocampal cells

LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death

G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

Bi-directional regulation of AIMP2 and its splice variant on PARP-1-dependent neuronal cell death; Therapeutic implication for Parkinson's disease

G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

Astrocytes in injury states rapidly produce anti‐inflammatory factors and attenuate microglial inflammatory responses

Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease

Effect of leucine-rich repeat kinase 2 (LRRK2) on protein synthesis

Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson's disease

Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1β-Mediated Inflammatory Signaling through Phosphorylation of RCAN1

Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein

Androstane metabolites bind to and deactivate the nuclear receptor CAR-β

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Leucine-rich Repeat Kinase 2 (LRRK2) Phosphorylates Rab10 in Glia and Neurons

Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Human zinc fingers as building blocks in the construction of artificial transcription factors

Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors

Characterization of Parkinson's disease-related pathogenic TMEM230 mutants

Regulation of the transcriptional activity of the tyrosine hydroxylase gene by androgen receptor

A Cofactor of tRNA Synthetase, p43, Is Secreted to Up-regulate Proinflammatory Genes

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