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Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses - are we our own worst enemy?

Nature reviews. Immunology, 2022-01, Vol.22 (1), p.47

2022

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PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization

The Journal of immunology (1950), 2017-09, Vol.199 (5), p.1846-1855

2017

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COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice

Nature (London), 2021-01, Vol.589 (7843), p.603-607

2021

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A molecular arms race between host innate antiviral response and emerging human coronaviruses

Virologica Sinica, 2016-02, Vol.31 (1), p.12-23

2016

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Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D

The Journal of clinical investigation, 2021-06, Vol.131 (11), p.1-14

2021

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Omicron subvariant BA.5 efficiently infects lung cells

Nature communications, 2023-06, Vol.14 (1), p.3500-3500, Article 3500

2023

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Identification of Lysine Acetylation Sites on MERS-CoV Replicase pp1ab

Molecular & cellular proteomics, 2020-08, Vol.19 (8), p.1303-1309

2020

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SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice

PLoS pathogens, 2022-09, Vol.18 (9), p.e1010782-e1010782

2022

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Contrasting roles of MERS-CoV and SARS-CoV-2 internal proteins in pathogenesis in mice

mBio, 2023-10, Vol.14 (6), p.e0247623-e0247623

2023

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Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3

Emerging microbes & infections, 2016-04, Vol.5 (1), p.e39-9

2016

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Proviral role of caspase-6 in coronavirus infections

Cell research, 2023-01, Vol.33 (1), p.7-8

2023

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Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2

STAR protocols, 2020-12, Vol.1 (3), p.100169-100169, Article 100169

2020

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SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

Nature (London), 2022-03, Vol.603 (7902), p.687-692

2022

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Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501YMA30 Strain of SARS-CoV-2

Vaccines (Basel), 2022-07, Vol.10 (8), p.1172

2022

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Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19

Nature (London), 2022-05, Vol.605 (7908), p.146-151

2022

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Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (29), p.1

2021

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Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (24), p.1

2021

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Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike

Proceedings of the National Academy of Sciences - PNAS, 2024-04, Vol.121 (15), p.e2317222121

2024

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Coronavirus-specific antibody production in middle-aged mice requires phospholipase [A.sub.2]G2D

The Journal of clinical investigation, 2021-06, Vol.131 (11)

2021

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Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε

The Journal of immunology (1950), 2020-09, Vol.205 (6), p.1564-1579

2020

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SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice

PLoS pathogens, 2022-09, Vol.18 (9), p.e1010782

2022

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Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.125-125.05

2022

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Identification of Lysine Acetylation Sites on MERS-CoV Replicase pp1ab

Molecular & cellular proteomics, 2020-08, Vol.19 (8), p.1303

2020

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Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501Y[sub.MA30] Strain of SARS-CoV-2

Vaccines (Basel), 2022-07, Vol.10 (8)

2022

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Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses - are we our own worst enemy?

PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization

COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice

Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment

A molecular arms race between host innate antiviral response and emerging human coronaviruses

Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D

Omicron subvariant BA.5 efficiently infects lung cells

Identification of Lysine Acetylation Sites on MERS-CoV Replicase pp1ab

SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice

Contrasting roles of MERS-CoV and SARS-CoV-2 internal proteins in pathogenesis in mice

Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3

Proviral role of caspase-6 in coronavirus infections

Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501YMA30 Strain of SARS-CoV-2

Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence

Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike

Coronavirus-specific antibody production in middle-aged mice requires phospholipase [A.sub.2]G2D

Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε

SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice

Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19

Identification of Lysine Acetylation Sites on MERS-CoV Replicase pp1ab

Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501Y[sub.MA30] Strain of SARS-CoV-2

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