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Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease

Oxidative medicine and cellular longevity, 2017-01, Vol.2017 (2017), p.1-18

2017

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Trojan horses and tunneling nanotubes enable α-synuclein pathology to spread in Parkinson disease

PLoS biology, 2021-07, Vol.19 (7), p.e3001331

2021

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α-synuclein and phosphoinositide-binding proteins: α-synuclein inhibits the association of PX- but not FYVE-containing proteins with vesicles in vivo

Biochemical and biophysical research communications, 2022-05, Vol.603, p.7-12

2022

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Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility

Scientific reports, 2023-06, Vol.13 (1), p.9243-9243, Article 9243

2023

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Possible regulation of the immune modulator tetraspanin CD81 by alpha-synuclein in melanoma

Biochemical and biophysical research communications, 2024-11, Vol.734, p.150631, Article 150631

2024

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Molecular Chaperones, Alpha-Synuclein, and Neurodegeneration

Molecular neurobiology, 2013-04, Vol.47 (2), p.552-560

Witt, Stephan N.

2013

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Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth

Scientific reports, 2021-03, Vol.11 (1), p.5267-5267, Article 5267

2021

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Phosphatidylethanolamine deficiency disrupts α-synuclein homeostasis in yeast and worm models of Parkinson disease

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (38), p.E3976-E3985

2014

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α-synuclein inhibits Snx3-retromer retrograde trafficking of the conserved membrane-bound proprotein convertase Kex2 in the secretory pathway of Saccharomyces cerevisiae

Human molecular genetics, 2022-03, Vol.31 (5), p.705-717

2022

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The small molecule triclabendazole decreases the intracellular level of cyclic AMP and increases resistance to stress in Saccharomyces cerevisiae

PloS one, 2013-05, Vol.8 (5), p.e64337-e64337

2013

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Hsp70 molecular chaperones and Parkinson's disease

Biopolymers, 2010-03, Vol.93 (3), p.218-228

Witt, Stephan N.

2010

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Alpha-synuclein inhibits Snx3-retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson's disease

Human molecular genetics, 2018-05, Vol.27 (9), p.1514-1532

2018

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Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease

PloS one, 2011-01, Vol.6 (1), p.e15946

2011

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Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease

PloS one, 2016-10, Vol.11 (10), p.e0164465

2016

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Loss of tumor suppressor menin expression in high grade cholangiocarcinomas

BMC research notes, 2023-02, Vol.16 (1), p.15-15, Article 15

2023

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Production of Fatty Acids and Protein by Nannochloropsis in Flat-Plate Photobioreactors

PloS one, 2017-01, Vol.12 (1), p.e0170440-e0170440

2017

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Plasma sphingolipid abnormalities in neurodegenerative diseases

PloS one, 2022-12, Vol.17 (12), p.e0279315-e0279315

2022

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ELISA method to detect α-synuclein oligomers in cell and animal models

PloS one, 2018-04, Vol.13 (4), p.e0196056

2018

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Queuine, a bacterial-derived hypermodified nucleobase, shows protection in in vitro models of neurodegeneration

PloS one, 2021-08, Vol.16 (8), p.e0253216

2021

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Lipid disequilibrium in biological membranes, a possible pathway to neurodegeneration

Communicative & integrative biology, 2014-12, Vol.7 (6), p.e993266-e993266

Witt, Stephan N.

2014

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Proteasome impairment by α-synuclein

PloS one, 2017-09, Vol.12 (9), p.e0184040-e0184040

2017

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α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (40), p.16119-16124

2012

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Human cerebrospinal fluid fatty acid levels differ between supernatant fluid and brain-derived nanoparticle fractions, and are altered in Alzheimer's disease

PloS one, 2014-06, Vol.9 (6), p.e100519

2014

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A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils

PloS one, 2024, Vol.19 (8), p.e0308521

2024

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Metabolomic and transcriptomic analyses of Fmo5-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress response, unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism

PloS one, 2023-06, Vol.18 (6), p.e0286692-e0286692

2023

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Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease

Trojan horses and tunneling nanotubes enable α-synuclein pathology to spread in Parkinson disease

α-synuclein and phosphoinositide-binding proteins: α-synuclein inhibits the association of PX- but not FYVE-containing proteins with vesicles in vivo

Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility

Possible regulation of the immune modulator tetraspanin CD81 by alpha-synuclein in melanoma

Molecular Chaperones, Alpha-Synuclein, and Neurodegeneration

Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth

Phosphatidylethanolamine deficiency disrupts α-synuclein homeostasis in yeast and worm models of Parkinson disease

α-synuclein inhibits Snx3-retromer retrograde trafficking of the conserved membrane-bound proprotein convertase Kex2 in the secretory pathway of Saccharomyces cerevisiae

The small molecule triclabendazole decreases the intracellular level of cyclic AMP and increases resistance to stress in Saccharomyces cerevisiae

Hsp70 molecular chaperones and Parkinson's disease

Alpha-synuclein inhibits Snx3-retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson's disease

Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease

Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease

Loss of tumor suppressor menin expression in high grade cholangiocarcinomas

Production of Fatty Acids and Protein by Nannochloropsis in Flat-Plate Photobioreactors

Plasma sphingolipid abnormalities in neurodegenerative diseases

ELISA method to detect α-synuclein oligomers in cell and animal models

Queuine, a bacterial-derived hypermodified nucleobase, shows protection in in vitro models of neurodegeneration

Lipid disequilibrium in biological membranes, a possible pathway to neurodegeneration

Proteasome impairment by α-synuclein

α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2

Human cerebrospinal fluid fatty acid levels differ between supernatant fluid and brain-derived nanoparticle fractions, and are altered in Alzheimer's disease

A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils

Metabolomic and transcriptomic analyses of Fmo5-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress response, unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism

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