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Glycosyltransferases: structures, functions, and mechanisms

Annual review of biochemistry, 2008-01, Vol.77 (1), p.521-555

2008

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N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases

Chemical communications (Cambridge, England), 2016-01, Vol.52 (51), p.7943-7946

2016

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Understanding viral neuraminidase inhibition by substituted difluorosialic acids

Chemical communications (Cambridge, England), 2015-02, Vol.51 (14), p.2933-2935

2015

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Mechanisms of glycosyl transferases and hydrolases

Carbohydrate polymers, 2001-04, Vol.44 (4), p.325-337

Withers, S.G

2001

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A Structural View of the Action of Escherichia coli (lacZ) β-Galactosidase

Biochemistry (Easton), 2001-12, Vol.40 (49), p.14781-14794

2001

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Bone morphogenetic protein-7 enhances dendritic growth and receptivity to innervation in cultured hippocampal neurons

The European journal of neuroscience, 2000-01, Vol.12 (1), p.106-116

2000

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Dissecting the Electrostatic Interactions and pH-Dependent Activity of a Family 11 Glycosidase

Biochemistry (Easton), 2001-08, Vol.40 (34), p.10115-10139

2001

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Identification of the Acid/Base Catalyst in Agrobacterium faecalis .beta.-Glucosidase by Kinetic Analysis of Mutants

Biochemistry (Easton), , Vol.34 (44), p.14554-14562

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The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode

Glycobiology (Oxford), 2013-09, Vol.23 (9), p.1075-1083

2013

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Phosphodiesters serve as potentially tunable aglycones for fluoro sugar inactivators of retaining β-glycosidases

Organic & biomolecular chemistry, 2014-04, Vol.12 (16), p.2592-2595

2014

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Engineering of a thioglycoligase: randomized mutagenesis of the acid–base residue leads to the identification of improved catalysts

Protein engineering, design and selection, 2005-01, Vol.18 (1), p.33-40

2005

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Structure and Mechanism of Chitin Deacetylase from the Fungal Pathogen Colletotrichum lindemuthianum

Biochemistry (Easton), 2006-08, Vol.45 (31), p.9416-9426

2006

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Glycosidase Mechanisms: Anatomy of a Finely Tuned Catalyst

Accounts of chemical research, 2000-01, Vol.33 (1), p.11-18

2000

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Approaches to labeling and identification of active site residues in glycosidases

Protein science, 1995-03, Vol.4 (3), p.361-372

1995

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Mechanism of Agrobacterium .beta.-glucosidase: kinetic studies

Biochemistry (Easton), , Vol.31 (41), p.9961-9969

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Glycosidase mechanisms

Current Opinion in Chemical Biology, 2000-10, Vol.4 (5), p.573-580

2000

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A simple dynamic model that accounts for regulation of neuronal polarity

Journal of integrative neuroscience, 2018-11, Vol.17 (4), p.323-330

J.E. Lugo, S. Mejia-Romero, R. Doti, K. Ray, S.L. Kothari, G. S. Withers, J. Faubert

2018

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Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

Nature (London), 2001-08, Vol.412 (6849), p.835-838

2001

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Glu-537, not Glu-461, is the nucleophile in the active site of (lac Z) beta-galactosidase from Escherichia coli

The Journal of biological chemistry, 1992-06, Vol.267 (16), p.11126-11130

1992

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X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the α-amylase family

Nature structural biology, 1999-05, Vol.6 (5), p.432-436

1999

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Stereoselective hydrolysis catalyzed by related beta-1,4-glucanases and beta-1,4-xylanases

The Journal of biological chemistry, 1992-06, Vol.267 (18), p.12559-12561

1992

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Detailed Structural Analysis of Glycosidase/Inhibitor Interactions: Complexes of Cex from Cellulomonas fimi with Xylobiose-Derived Aza-Sugars

Biochemistry (Easton), 2000-09, Vol.39 (38), p.11553-11563

2000

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Changing Enzymic Reaction Mechanisms by Mutagenesis: Conversion of a Retaining Glucosidase to an Inverting Enzyme

Journal of the American Chemical Society, 1994-12, Vol.116 (25), p.11594-11595

1994

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Structure-based mutagenic analysis of mechanism and substrate specificity in mammalian glycosyltransferases: porcine ST3Gal-I

Glycobiology (Oxford), 2013-05, Vol.23 (5), p.536-545

2013

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Identification of the catalytic nucleophile of the Family 31 alpha-glucosidase from Aspergillus niger via trapping of a 5-fluoroglycosyl-enzyme intermediate

Biochemical journal, 2001-10, Vol.359 (Pt 2), p.381-386

2001

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Glycosyltransferases: structures, functions, and mechanisms

N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases

Understanding viral neuraminidase inhibition by substituted difluorosialic acids

Mechanisms of glycosyl transferases and hydrolases

A Structural View of the Action of Escherichia coli (lacZ) β-Galactosidase

Bone morphogenetic protein-7 enhances dendritic growth and receptivity to innervation in cultured hippocampal neurons

Dissecting the Electrostatic Interactions and pH-Dependent Activity of a Family 11 Glycosidase

Identification of the Acid/Base Catalyst in Agrobacterium faecalis .beta.-Glucosidase by Kinetic Analysis of Mutants

The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode

Phosphodiesters serve as potentially tunable aglycones for fluoro sugar inactivators of retaining β-glycosidases

Engineering of a thioglycoligase: randomized mutagenesis of the acid–base residue leads to the identification of improved catalysts

Structure and Mechanism of Chitin Deacetylase from the Fungal Pathogen Colletotrichum lindemuthianum

Glycosidase Mechanisms: Anatomy of a Finely Tuned Catalyst

Approaches to labeling and identification of active site residues in glycosidases

Mechanism of Agrobacterium .beta.-glucosidase: kinetic studies

Glycosidase mechanisms

A simple dynamic model that accounts for regulation of neuronal polarity

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

Glu-537, not Glu-461, is the nucleophile in the active site of (lac Z) beta-galactosidase from Escherichia coli

X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the α-amylase family

Stereoselective hydrolysis catalyzed by related beta-1,4-glucanases and beta-1,4-xylanases

Detailed Structural Analysis of Glycosidase/Inhibitor Interactions: Complexes of Cex from Cellulomonas fimi with Xylobiose-Derived Aza-Sugars

Changing Enzymic Reaction Mechanisms by Mutagenesis: Conversion of a Retaining Glucosidase to an Inverting Enzyme

Structure-based mutagenic analysis of mechanism and substrate specificity in mammalian glycosyltransferases: porcine ST3Gal-I

Identification of the catalytic nucleophile of the Family 31 alpha-glucosidase from Aspergillus niger via trapping of a 5-fluoroglycosyl-enzyme intermediate

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