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Acetaminophen-induced liver injury in rats and mice: Comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity

Toxicology and applied pharmacology, 2012-11, Vol.264 (3), p.387-394

2012

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Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity

Liver international, 2012-01, Vol.32 (1), p.8-20

2012

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The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

The Journal of clinical investigation, 2012-04, Vol.122 (4), p.1574-1583

2012

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Readers of DNA methylation, the MBD family as potential therapeutic targets

Pharmacology & therapeutics (Oxford), 2018-04, Vol.184, p.98-111

2018

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Dual Inhibition of Bcl-2 and Bcl-xL Strikingly Enhances PI3K Inhibition-Induced Apoptosis in Human Myeloid Leukemia Cells through a GSK3- and Bim-Dependent Mechanism

Cancer research (Chicago, Ill.), 2013-02, Vol.73 (4), p.1340-1351

2013

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Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase

Toxicology and applied pharmacology, 2014-11, Vol.281 (1), p.58-66

2014

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The Methyl-CpG–Binding Domain 2 and 3 Proteins and Formation of the Nucleosome Remodeling and Deacetylase Complex

Journal of molecular biology, 2020-03, Vol.432 (6), p.1624-1639

2020

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Sarcopenia is a predictor of outcomes in very elderly patients undergoing emergency surgery

Surgery, 2014-09, Vol.156 (3), p.521-527

2014

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MBD2a-NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression

Proceedings of the National Academy of Sciences - PNAS, 2023-06, Vol.120 (25), p.e2302254120-e2302254120

2023

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Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans

Toxicology and applied pharmacology, 2014-03, Vol.275 (2), p.122-133

2014

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DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice

eLife, 2023-04, Vol.12

2023

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A Bayesian framework for the detection of diffusive heterogeneity

PloS one, 2020-05, Vol.15 (5), p.e0221841-e0221841

2020

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Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: Dose–response, mechanisms, and clinical implications

Toxicology and applied pharmacology, 2013-06, Vol.269 (3), p.240-249

2013

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Structural Basis of MeCP2 Distribution on Non-CpG Methylated and Hydroxymethylated DNA

Journal of molecular biology, 2017-05, Vol.429 (10), p.1581-1594

2017

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Analysis of the complex between MBD2 and the histone deacetylase core of NuRD reveals key interactions critical for gene silencing

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (33), p.e2307287120-e2307287120

2023

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Pigeons trade efficiency for stability in response to level of challenge during confined flight

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (11), p.3392-3396

2015

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Methylation specific targeting of a chromatin remodeling complex from sponges to humans

Scientific reports, 2017-01, Vol.7 (1), p.40674-40674, Article 40674

2017

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Evaluation of acyllysine isostere interactions with the aromatic pocket of the AF9 YEATS domain

Protein science, 2023-01, Vol.32 (1), p.e4533-n/a

2023

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The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture

Cell reports (Cambridge), 2020-12, Vol.33 (9), p.108450-108450, Article 108450

2020

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A MEIG1/PACRG complex in the manchette is essential for building the sperm flagella

Development (Cambridge), 2015-03, Vol.142 (5), p.921-930

2015

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Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target-methylated DNA sequence

Nucleic acids research, 2011-08, Vol.39 (15), p.6741

2011

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Probing the dynamic distribution of bound states for methylcytosine-binding domains on DNA

The Journal of biological chemistry, 2014-01, Vol.289 (3), p.1294-1302

2014

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Densely methylated DNA traps Methyl-CpG–binding domain protein 2 but permits free diffusion by Methyl-CpG–binding domain protein 3

The Journal of biological chemistry, 2022-10, Vol.298 (10), p.102428, Article 102428

2022

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Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process

Blood, 2012-06, Vol.119 (25), p.6089-6098

2012

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Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human adult erythroid cells

Haematologica (Roma), 2019-12, Vol.104 (12), p.2361-2371

2019

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Acetaminophen-induced liver injury in rats and mice: Comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity

Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

Readers of DNA methylation, the MBD family as potential therapeutic targets

Dual Inhibition of Bcl-2 and Bcl-xL Strikingly Enhances PI3K Inhibition-Induced Apoptosis in Human Myeloid Leukemia Cells through a GSK3- and Bim-Dependent Mechanism

Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase

The Methyl-CpG–Binding Domain 2 and 3 Proteins and Formation of the Nucleosome Remodeling and Deacetylase Complex

Sarcopenia is a predictor of outcomes in very elderly patients undergoing emergency surgery

MBD2a-NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression

Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans

DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice

A Bayesian framework for the detection of diffusive heterogeneity

Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: Dose–response, mechanisms, and clinical implications

Structural Basis of MeCP2 Distribution on Non-CpG Methylated and Hydroxymethylated DNA

Analysis of the complex between MBD2 and the histone deacetylase core of NuRD reveals key interactions critical for gene silencing

Pigeons trade efficiency for stability in response to level of challenge during confined flight

Methylation specific targeting of a chromatin remodeling complex from sponges to humans

Evaluation of acyllysine isostere interactions with the aromatic pocket of the AF9 YEATS domain

The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture

A MEIG1/PACRG complex in the manchette is essential for building the sperm flagella

Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target-methylated DNA sequence

Probing the dynamic distribution of bound states for methylcytosine-binding domains on DNA

Densely methylated DNA traps Methyl-CpG–binding domain protein 2 but permits free diffusion by Methyl-CpG–binding domain protein 3

Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process

Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human adult erythroid cells

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