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Computational Chemistry in the Pharmaceutical Industry: From Childhood to Adolescence

ChemMedChem, 2015-12, Vol.10 (12), p.1958-1962

2015

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The importance of chemistry for the future of the pharma industry

Angewandte Chemie International Edition, 2011-08, Vol.50 (33), p.7452-7453

2011

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Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2775-2778

2001

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"Collaborative Innovation"-Regaining the Edge in Drug Discovery

Angewandte Chemie (International ed.), 2013-03, Vol.52 (10), p.2684-2687

International ed. in English, 2013

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"Collaborative Innovation" - Wie bringt man die Arzneimittelentwicklung zurück auf die Erfolgsspur?

Angewandte Chemie, 2013-03, Vol.125 (10), p.2748-2751

2013

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Editorial: The Importance of Chemistry for the Future of the Pharma Industry

Angewandte Chemie (International ed.), 2011-08, Vol.50 (33), p.7452-7453

International ed. in English, 2011

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Abstract 855: Increased in vitro potency and in vivo efficacy of FGFR2-targeted thorium-227 conjugate (FGFR2-TTC) in combination with the ATR inhibitor BAY 1895344

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.855-855

2018

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Abstract 849: Synergistic effect of MSLN-TTC in combination with DNA damage response inhibitors

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.849-849

2018

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Abstract 850: Mesothelin targeted thorium-227 conjugate (MSLN-TTC): Preclinical evaluation of a new targeted alpha therapeutic in mesothelin-positive cancers

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.850-850

2018

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Abstract 5199: Preclinical activity of the FGFR2-targeted thorium-227 conjugate in preclinical models of colorectal, gastric and triple-negative breast cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5199-5199

2017

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Editorial: Die Bedeutung der Chemie für die Zukunft der Pharmaindustrie

Angewandte Chemie, 2011-08, Vol.123 (33), p.7590-7592

2011

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Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits

Drug discovery today, 2006-02, Vol.11 (3-4), p.175-180

2006

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One target – multiple indications: a call for an integrated common mechanisms strategy

Drug discovery today, 2007-12, Vol.12 (23), p.1025-1031

2007

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Enantioselective Total Synthesis of the Antifungal Natural Products Chlorotetaine, Bacilysin, and Anticapsin and of Related Compounds: Revision of the Relative Configuration

Journal of organic chemistry, 1994-05, Vol.59 (10), p.2748-2761

Wild, Hanno

1994

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Are 6-acylamino oxazoline stable compounds?

Tetrahedron letters, 1993, Vol.34 (2), p.285-288

Wild, Hanno

1993

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ChemInform Abstract: Computational Chemistry in the Pharmaceutical Industry: From Childhood to Adolescence

ChemInform, 2015-12, Vol.47 (3), p.no-no

2015

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p38 Kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (1), p.9-12

2001

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First Synthetic Access to 6-(Methylene)oxapenems: A New Class of ß-Lactamase Inhibitors

Synthesis (Stuttgart), 1992, Vol.1992 (11), p.1099-1103

1992

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Enantioselective and Diastereoselective Total Synthesis of the Antimycotically Active Natural Product Chlorotetaine: Revision of the Relative Configuration

Angewandte Chemie (International ed.), 1991-12, Vol.30 (12), p.1685-1687

1991

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Lewis-Säure-katalysierte Umlagerung von 2-Allyl-5(2H)-oxazolonen in Tetrahdro-3H-furo[3,4-b]pyrrol-Derivate

Liebigs Annalen der Chemie, 1986-11, Vol.1986 (11), p.1910-1913

1986

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Preparation of functionalized hydroindol-3-ols via tandem aza-Cope rearrangement-mannich cyclizations. Formal total synthesis of (±)-6a-epipretazettine and related alkaloids

Tetrahedron letters, 1989, Vol.30 (6), p.647-650

1989

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Enantio- und diastereoselektive Totalsynthese des antimykotisch wirkenden Naturstoffes Chlorotetain: Revision der relativen Konfiguration

Angewandte Chemie, 1991-12, Vol.103 (12), p.1729-1731

1991

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Enantio‐ und diastereoselektive Totalsynthese des antimykotisch wirkenden Naturstoffes Chlorotetain: Revision der relativen Konfiguration

Angewandte Chemie, 1991-12, Vol.103 (12), p.1729-1731

1991

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Substituted 6-alkyloxapenems: potent β-lactamase inhibitors: synthesis and biological characterization

Bioorganic & medicinal chemistry letters, 1993-11, Vol.3 (11), p.2205-2210

1993

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First synthetic access to 6-(methylene)oxapenems : a new class of β-lactamase inhibitors

Synthesis (Stuttgart), 1992, Vol.1992 (11), p.1099-1103

1992

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Computational Chemistry in the Pharmaceutical Industry: From Childhood to Adolescence

The importance of chemistry for the future of the pharma industry

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

"Collaborative Innovation"-Regaining the Edge in Drug Discovery

"Collaborative Innovation" - Wie bringt man die Arzneimittelentwicklung zurück auf die Erfolgsspur?

Editorial: The Importance of Chemistry for the Future of the Pharma Industry

Abstract 855: Increased in vitro potency and in vivo efficacy of FGFR2-targeted thorium-227 conjugate (FGFR2-TTC) in combination with the ATR inhibitor BAY 1895344

Abstract 849: Synergistic effect of MSLN-TTC in combination with DNA damage response inhibitors

Abstract 850: Mesothelin targeted thorium-227 conjugate (MSLN-TTC): Preclinical evaluation of a new targeted alpha therapeutic in mesothelin-positive cancers

Abstract 5199: Preclinical activity of the FGFR2-targeted thorium-227 conjugate in preclinical models of colorectal, gastric and triple-negative breast cancer

Editorial: Die Bedeutung der Chemie für die Zukunft der Pharmaindustrie

Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits

One target – multiple indications: a call for an integrated common mechanisms strategy

Enantioselective Total Synthesis of the Antifungal Natural Products Chlorotetaine, Bacilysin, and Anticapsin and of Related Compounds: Revision of the Relative Configuration

Are 6-acylamino oxazoline stable compounds?

ChemInform Abstract: Computational Chemistry in the Pharmaceutical Industry: From Childhood to Adolescence

p38 Kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas

First Synthetic Access to 6-(Methylene)oxapenems: A New Class of ß-Lactamase Inhibitors

Enantioselective and Diastereoselective Total Synthesis of the Antimycotically Active Natural Product Chlorotetaine: Revision of the Relative Configuration

Lewis-Säure-katalysierte Umlagerung von 2-Allyl-5(2H)-oxazolonen in Tetrahdro-3H-furo[3,4-b]pyrrol-Derivate

Preparation of functionalized hydroindol-3-ols via tandem aza-Cope rearrangement-mannich cyclizations. Formal total synthesis of (±)-6a-epipretazettine and related alkaloids

Enantio- und diastereoselektive Totalsynthese des antimykotisch wirkenden Naturstoffes Chlorotetain: Revision der relativen Konfiguration

Enantio‐ und diastereoselektive Totalsynthese des antimykotisch wirkenden Naturstoffes Chlorotetain: Revision der relativen Konfiguration

Substituted 6-alkyloxapenems: potent β-lactamase inhibitors: synthesis and biological characterization

First synthetic access to 6-(methylene)oxapenems : a new class of β-lactamase inhibitors

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