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Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs

The European respiratory journal, 2023-08, Vol.62 (2), p.2300165

2023

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Finding the right hazard function for time‐to‐event modeling: A tutorial and Shiny application

CPT: pharmacometrics and systems pharmacology, 2022-08, Vol.11 (8), p.991-1001

2022

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Integration of PKPD relationships into benefit–risk analysis

British journal of clinical pharmacology, 2015-11, Vol.80 (5), p.979-991

2015

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Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae

Scientific reports, 2019-02, Vol.9 (1), p.2149, Article 2149

2019

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Reproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19

Scientific reports, 2023-09, Vol.13 (1), p.16292-16292, Article 16292

2023

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Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans

British journal of pharmacology, 2020-12, Vol.177 (24), p.5518-5533

2020

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Seasonal influence on respiratory tract infection severity including COVID-19 quantified through Markov Chain modeling

CPT: pharmacometrics and systems pharmacology, 2023-09, Vol.12 (9), p.1250-1261

2023

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Pharmacokinetic analysis across studies to drive knowledge-integration: A tutorial on individual patient data meta-analysis (IPDMA)

CPT: pharmacometrics and systems pharmacology, 2023-09, Vol.12 (9), p.1187-1200

2023

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Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy

CPT: pharmacometrics and systems pharmacology, 2023-07, Vol.12 (7), p.977-987

2023

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Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trial

EClinicalMedicine, 2022-06, Vol.48, p.101414, Article 101414

2022

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Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development

Frontiers in pharmacology, 2023, Vol.14, p.1150243

2023

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Risk Factors for COVID-19 and Respiratory Tract Infections during the Coronavirus Pandemic

Vaccines (Basel), 2024-03, Vol.12 (3), p.329

2024

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Segmentation-Driven Optimization For Iterative Reconstruction in Optical Projection Tomography: An Exploration

IEEE transactions on computational imaging, 2020, Vol.6, p.1537-1547

2020

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Model-Informed Drug Discovery and Development Strategy for the Rapid Development of Anti-Tuberculosis Drug Combinations

Applied Sciences (Bucuresti), 2020-04, Vol.10 (7), p.2376

2020

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Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium

iScience, 2023-04, Vol.26 (4), p.106411-106411, Article 106411

2023

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Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol

The Journal of pharmacology and experimental therapeutics, 2019-10, Vol.371 (1), p.15-24

2019

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Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude

Zebrafish, 2016-12, Vol.13 (6), p.54-510

2016

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Development of a population pharmacokinetic model to predict brain distribution and dopamine D2 receptor occupancy of raclopride in non-anesthetized rat

European journal of pharmaceutical sciences, 2018-01, Vol.111, p.514-525

2018

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Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development

Clinical and translational science, 2020-11, Vol.13 (6), p.1060-1064

2020

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Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies

CPT: pharmacometrics and systems pharmacology, 2018-05, Vol.7 (5), p.285-287

2018

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Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial

American journal of respiratory and critical care medicine, 2022-05, Vol.205 (10), p.1228-1235

2022

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Systems pharmacology of hepatic metabolism in zebrafish larvae

Drug discovery today. Disease models, 2016, Vol.22, p.27-34

2016

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Safety and Efficacy of BCG Re-Vaccination in Reducing COVID-19 Morbidity in Healthcare Workers: A Double-Blind, Randomised, Controlled, Phase 3 Trial

SSRN Electronic Journal

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Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs

Finding the right hazard function for time‐to‐event modeling: A tutorial and Shiny application

Integration of PKPD relationships into benefit–risk analysis

Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae

Reproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19

Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans

Seasonal influence on respiratory tract infection severity including COVID-19 quantified through Markov Chain modeling

Pharmacokinetic analysis across studies to drive knowledge-integration: A tutorial on individual patient data meta-analysis (IPDMA)

Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy

Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trial

Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development

Risk Factors for COVID-19 and Respiratory Tract Infections during the Coronavirus Pandemic

Segmentation-Driven Optimization For Iterative Reconstruction in Optical Projection Tomography: An Exploration

Model-Informed Drug Discovery and Development Strategy for the Rapid Development of Anti-Tuberculosis Drug Combinations

Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium

Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol

Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude

Development of a population pharmacokinetic model to predict brain distribution and dopamine D2 receptor occupancy of raclopride in non-anesthetized rat

Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development

Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies

Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial

Systems pharmacology of hepatic metabolism in zebrafish larvae

Implementing best practices on data generation and reporting of Mycobacterium tuberculosisin vitro assays within the ERA4TB consortium

Implementing Best Practises on Data Generation and Reporting of Mycobacterium tuberculosis Time Kill Assays: A Case Study of Standardized Protocol Within the ERA4TB Consortium

Safety and Efficacy of BCG Re-Vaccination in Reducing COVID-19 Morbidity in Healthcare Workers: A Double-Blind, Randomised, Controlled, Phase 3 Trial

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