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PI5P and PI(3,5)P2: Minor, but Essential Phosphoinositides

Cell Structure and Function, 2017, Vol.42(1), pp.49-60

2017

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Phosphatidylinositol 3,5-bisphosphate: regulation of cellular events in space and time

Biochemical Society transactions, 2016-02, Vol.44 (1), p.177-184

2016

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Phosphatidylinositol 3,5-bisphosphate: Low abundance, high significance

BioEssays, 2014-01, Vol.36 (1), p.52-64

2014

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A TRP Channel in the Lysosome Regulates Large Particle Phagocytosis via Focal Exocytosis

Developmental cell, 2013-09, Vol.26 (5), p.511-524

2013

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PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity

Molecular biology of the cell, 2022-03, Vol.33 (3), p.ar26-ar26

2022

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PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

Nature communications, 2010-07, Vol.1 (1), p.38, Article 38

2010

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The vacuole/lysosome is required for cell-cycle progression

eLife, 2015-08, Vol.4

2015

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Myosin V Transports Secretory Vesicles via a Rab GTPase Cascade and Interaction with the Exocyst Complex

Developmental cell, 2011-12, Vol.21 (6), p.1156-1170

2011

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Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (52), p.21165-21170

2013

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Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1

Molecular biology of the cell, 2012-08, Vol.23 (15), p.2955-2962

2012

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In vivo, Pikfyve generates PI(3,5)P₂, which serves as both a signaling lipid and the major precursor for PI5P

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (43), p.17472-17477

2012

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Vacuole-mediated selective regulation of TORC1-Sch9 signaling following oxidative stress

Molecular biology of the cell, 2018-02, Vol.29 (4), p.510-522

2018

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The PIKfyve complex regulates the early melanosome homeostasis required for physiological amyloid formation

Journal of cell science, 2019-02, Vol.132 (5)

2019

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Organelles on the move: insights from yeast vacuole inheritance

Nature reviews. Molecular cell biology, 2006-04, Vol.7 (4), p.243-252

Weisman, Lois S

2006

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Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies

PLoS genetics, 2011-10, Vol.7 (10), p.e1002319-e1002319

2011

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Overlap of cargo binding sites on myosin V coordinates the inheritance of diverse cargoes

The Journal of cell biology, 2012-07, Vol.198 (1), p.69-85

2012

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Spatial regulation of organelle release from myosin V transport by p21-activated kinases

The Journal of cell biology, 2017-06, Vol.216 (6), p.1557-1566

2017

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VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse

The EMBO journal, 2008-12, Vol.27 (24), p.3221-3234

2008

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Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J

PLoS genetics, 2011-06, Vol.7 (6), p.e1002104-e1002104

2011

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Early protection to stress mediated by CDK-dependent PI3,5P2 signaling from the vacuole/lysosome

The Journal of cell biology, 2017-07, Vol.216 (7), p.2075-2090

2017

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Roles of PIKfyve in multiple cellular pathways

Current opinion in cell biology, 2022-06, Vol.76, p.102086-102086, Article 102086

2022

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Activity-dependent PI(3,5)P₂ synthesis controls AMPA receptor trafficking during synaptic depression

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (45), p.E4896-E4905

2014

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Close Encounters of the Lysosome-Peroxisome Kind

Cell, 2015-04, Vol.161 (2), p.197-198

2015

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Release from Myosin V via Regulated Recruitment of an E3 Ubiquitin Ligase Controls Organelle Localization

Developmental cell, 2014-03, Vol.28 (5), p.520-533

2014

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PI5P and PI(3,5)P2: Minor, but Essential Phosphoinositides

Phosphatidylinositol 3,5-bisphosphate: regulation of cellular events in space and time

Phosphatidylinositol 3,5-bisphosphate: Low abundance, high significance

A TRP Channel in the Lysosome Regulates Large Particle Phagocytosis via Focal Exocytosis

PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

The vacuole/lysosome is required for cell-cycle progression

Myosin V Transports Secretory Vesicles via a Rab GTPase Cascade and Interaction with the Exocyst Complex

Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics

Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1

In vivo, Pikfyve generates PI(3,5)P₂, which serves as both a signaling lipid and the major precursor for PI5P

Vacuole-mediated selective regulation of TORC1-Sch9 signaling following oxidative stress

The PIKfyve complex regulates the early melanosome homeostasis required for physiological amyloid formation

Organelles on the move: insights from yeast vacuole inheritance

Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies

Overlap of cargo binding sites on myosin V coordinates the inheritance of diverse cargoes

Spatial regulation of organelle release from myosin V transport by p21-activated kinases

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse

Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J

Early protection to stress mediated by CDK-dependent PI3,5P2 signaling from the vacuole/lysosome

Roles of PIKfyve in multiple cellular pathways

Activity-dependent PI(3,5)P₂ synthesis controls AMPA receptor trafficking during synaptic depression

Close Encounters of the Lysosome-Peroxisome Kind

Release from Myosin V via Regulated Recruitment of an E3 Ubiquitin Ligase Controls Organelle Localization

Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein

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