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Depletion of antibiotic targets has widely varying effects on growth

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (10), p.4176-4181

2011

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A pathway-directed positive growth restoration assay to facilitate the discovery of lipid A and fatty acid biosynthesis inhibitors in Acinetobacter baumannii

PloS one, 2018-03, Vol.13 (3), p.e0193851

2018

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Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606

PloS one, 2016-08, Vol.11 (8), p.e0160918

2016

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A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria

Science signaling, 2012-01, Vol.5 (208), p.ra7

2012

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Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis

PLoS pathogens, 2014-03, Vol.10 (3), p.e1003994

2014

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Lipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosis

PLoS pathogens, 2015-03, Vol.11 (3), p.e1004792-e1004792

2015

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Inhibition of Bacterial Disulfide Bond Formation by the Anticoagulant Warfarin

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (1), p.297-301

2010

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Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (4), p.1257-1262

2012

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LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates

mSphere, 2017-07, Vol.2 (4)

2017

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Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Immunity (Cambridge, Mass.), 2022-05, Vol.55 (5), p.827-846.e10

2022

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Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis

mSphere, 2018-10, Vol.3 (5)

2018

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The LuxR family protein SpnR functions as a negative regulator of N‐acylhomoserine lactone‐dependent quorum sensing in Serratia marcescens

Molecular microbiology, 2002-09, Vol.45 (6), p.1655-1671

2002

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The Abyssomicin C family as in vitro inhibitors of Mycobacterium tuberculosis

Tuberculosis (Edinburgh, Scotland), 2010-09, Vol.90 (5), p.298-300

2010

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RssAB signaling coordinates early development of surface multicellularity in Serratia marcescens

PloS one, 2011-08, Vol.6 (8), p.e24154-e24154

2011

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Role of Metal-Dependent Regulation of ESX-3 Secretion in Intracellular Survival of Mycobacterium tuberculosis

Infection and immunity, 2016-08, Vol.84 (8), p.2255-2263

2016

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The RssAB Two-Component Signal Transduction System in Serratia marcescens Regulates Swarming Motility and Cell Envelope Architecture in Response to Exogenous Saturated Fatty Acids

Journal of Bacteriology, 2005-05, Vol.187 (10), p.3407-3414

2005

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Pirin Regulates Pyruvate Catabolism by Interacting with the Pyruvate Dehydrogenase E1 Subunit and Modulating Pyruvate Dehydrogenase Activity

Journal of Bacteriology, 2007-01, Vol.189 (1), p.109-118

2007

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A Mobile Quorum-Sensing System in Serratia marcescens

Journal of Bacteriology, 2006-02, Vol.188 (4), p.1518-1525

2006

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SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance

Journal of antimicrobial chemotherapy, 2021-08, Vol.76 (8), p.2049-2056

2021

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Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae

Antimicrobial agents and chemotherapy, 2018-10, Vol.62 (10)

2018

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Regulation of Swarming Motility and flhDCSm Expression by RssAB Signaling in Serratia marcescens

Journal of Bacteriology, 2008-04, Vol.190 (7), p.2496-2504

2008

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Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase

Nucleic acids research, 2011-03, Vol.39 (6), p.2210

2011

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Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3325-3349

2018

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Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3309-3324

2018

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Direct and Simultaneous Identification of Mycobacterium tuberculosis complex (MTBC) and Mycobacterium tuberculosis (MTB) by Rapid Multiplex nested PCR-ICT assay

Journal of microbiological methods, 2006-09, Vol.66 (3), p.440-448

2006

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Depletion of antibiotic targets has widely varying effects on growth

A pathway-directed positive growth restoration assay to facilitate the discovery of lipid A and fatty acid biosynthesis inhibitors in Acinetobacter baumannii

Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606

A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria

Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis

Lipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosis

Inhibition of Bacterial Disulfide Bond Formation by the Anticoagulant Warfarin

Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis

LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis

The LuxR family protein SpnR functions as a negative regulator of N‐acylhomoserine lactone‐dependent quorum sensing in Serratia marcescens

The Abyssomicin C family as in vitro inhibitors of Mycobacterium tuberculosis

RssAB signaling coordinates early development of surface multicellularity in Serratia marcescens

Role of Metal-Dependent Regulation of ESX-3 Secretion in Intracellular Survival of Mycobacterium tuberculosis

The RssAB Two-Component Signal Transduction System in Serratia marcescens Regulates Swarming Motility and Cell Envelope Architecture in Response to Exogenous Saturated Fatty Acids

Pirin Regulates Pyruvate Catabolism by Interacting with the Pyruvate Dehydrogenase E1 Subunit and Modulating Pyruvate Dehydrogenase Activity

A Mobile Quorum-Sensing System in Serratia marcescens

SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance

Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae

Regulation of Swarming Motility and flhDCSm Expression by RssAB Signaling in Serratia marcescens

Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase

Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity

Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria

Direct and Simultaneous Identification of Mycobacterium tuberculosis complex (MTBC) and Mycobacterium tuberculosis (MTB) by Rapid Multiplex nested PCR-ICT assay

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