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Biosynthesis of Bioactive Natural Products Derived from Theonellidae Family Marine Sponges

Chemical and Pharmaceutical Bulletin, 2023/01/01, Vol.71(1), pp.1-8

Wakimoto, Toshiyuki

2023

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Toward the Dark Matter of Natural Products

Chemical record, 2017-11, Vol.17 (11), p.1124-1134

Wakimoto, Toshiyuki

2017

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Streamlined Chemoenzymatic Synthesis of Cyclic Peptides by Non-ribosomal Peptide Cyclases

Journal of the American Chemical Society, 2023-02, Vol.145 (6), p.3270-3275

2023

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Complete Biosynthetic Pathway of Anditomin: Nature’s Sophisticated Synthetic Route to a Complex Fungal Meroterpenoid

Journal of the American Chemical Society, 2014-10, Vol.136 (43), p.15326-15336

2014

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Spiro-Ring Formation is Catalyzed by a Multifunctional Dioxygenase in Austinol Biosynthesis

Journal of the American Chemical Society, 2013-07, Vol.135 (30), p.10962-10965

2013

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Uncovering the Unusual D‑Ring Construction in Terretonin Biosynthesis by Collaboration of a Multifunctional Cytochrome P450 and a Unique Isomerase

Journal of the American Chemical Society, 2015-03, Vol.137 (9), p.3393-3401

2015

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Five New Analogs of Streptogramin Antibiotic Viridogrisein Isolated from Streptomyces niveoruber

Chemical and Pharmaceutical Bulletin, 2024/01/18, Vol.72(1), pp.80-85

2024

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Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria

Journal of the American Chemical Society, 2018-07, Vol.140 (29), p.9083-9086

2018

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New variochelins from soil-isolated Variovorax sp. H002

Beilstein journal of organic chemistry, 2024-04, Vol.20 (1), p.692-700

2024

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SurE is a trans-acting thioesterase cyclizing two distinct non-ribosomal peptides

Organic & biomolecular chemistry, 2019-01, Vol.17 (5), p.1058-1061

2019

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Total Synthesis of the Nonribosomal Peptide Surugamide B and Identification of a New Offloading Cyclase Family

Angewandte Chemie International Edition, 2018-07, Vol.57 (30), p.9447-9451

International ed. in English, 2018

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Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by 'Entotheonella'

PloS one, 2016-10, Vol.11 (10), p.e0164468-e0164468

2016

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Calyculin: Nature's way of making the sponge-derived cytotoxin

Natural product reports, 2016-06, Vol.33 (6), p.751-76

2016

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Geographical parthenogenesis in the brown alga Scytosiphon lomentaria (Scytosiphonaceae): Sexuals in warm waters and parthenogens in cold waters

Molecular ecology, 2021-11, Vol.30 (22), p.5814-5830

2021

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Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823

Journal of antibiotics, 2015-05, Vol.68 (5), p.342-344

2015

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A Natural Dihydropyridazinone Scaffold Generated from a Unique Substrate for a Hydrazine-Forming Enzyme

Journal of the American Chemical Society, 2022-07, Vol.144 (28), p.12954-12960

2022

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Chemoenzymatic tandem cyclization for the facile synthesis of bicyclic peptides

Communications chemistry, 2024-03, Vol.7 (1), p.67-67, Article 67

2024

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New Theonellapeptolides from Indonesian Marine Sponge Theonella swinhoei as Anti-Austerity Agents

Marine drugs, 2022-10, Vol.20 (11), p.661

2022

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A Methyltransferase Initiates Terpene Cyclization in Teleocidin B Biosynthesis

Journal of the American Chemical Society, 2014-07, Vol.136 (28), p.9910-9913

2014

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Biosynthetic Insights of Calyculin- and Misakinolide-Type Compounds in "Candidatus Entotheonella sp."

Methods in enzymology, 2018, Vol.604, p.287-330

2018

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Diastereoselective Total Synthesis and Structural Confirmation of Surugamide F

Chemical and Pharmaceutical Bulletin, 2018/06/01, Vol.66(6), pp.637-641

2018

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The Revised Structure of the Cyclic Octapeptide Surugamide A

Chemical and Pharmaceutical Bulletin, 2019/05/01, Vol.67(5), pp.476-480

2019

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Scrobiculosides A and B from the deep-sea sponge Pachastrella scrobiculosa

Journal of natural medicines, 2019-09, Vol.73 (4), p.814-819

2019

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Crystal Structures of Flavone C-Glycosides from Oolong Tea Leaves: Chafuroside A Dihydrate and Chafuroside B Monohydrate

Chemical and Pharmaceutical Bulletin, 2019/09/01, Vol.67(9), pp.935-939

2019

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Furan fatty acid as an anti-inflammatory component from the green-lipped mussel Perna canaliculus

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (42), p.17533-17537

2011

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Biosynthesis of Bioactive Natural Products Derived from Theonellidae Family Marine Sponges

Toward the Dark Matter of Natural Products

Streamlined Chemoenzymatic Synthesis of Cyclic Peptides by Non-ribosomal Peptide Cyclases

Complete Biosynthetic Pathway of Anditomin: Nature’s Sophisticated Synthetic Route to a Complex Fungal Meroterpenoid

Spiro-Ring Formation is Catalyzed by a Multifunctional Dioxygenase in Austinol Biosynthesis

Uncovering the Unusual D‑Ring Construction in Terretonin Biosynthesis by Collaboration of a Multifunctional Cytochrome P450 and a Unique Isomerase

Five New Analogs of Streptogramin Antibiotic Viridogrisein Isolated from Streptomyces niveoruber

Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria

New variochelins from soil-isolated Variovorax sp. H002

SurE is a trans-acting thioesterase cyclizing two distinct non-ribosomal peptides

Total Synthesis of the Nonribosomal Peptide Surugamide B and Identification of a New Offloading Cyclase Family

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by 'Entotheonella'

Calyculin: Nature's way of making the sponge-derived cytotoxin

Geographical parthenogenesis in the brown alga Scytosiphon lomentaria (Scytosiphonaceae): Sexuals in warm waters and parthenogens in cold waters

Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823

A Natural Dihydropyridazinone Scaffold Generated from a Unique Substrate for a Hydrazine-Forming Enzyme

Chemoenzymatic tandem cyclization for the facile synthesis of bicyclic peptides

New Theonellapeptolides from Indonesian Marine Sponge Theonella swinhoei as Anti-Austerity Agents

A Methyltransferase Initiates Terpene Cyclization in Teleocidin B Biosynthesis

Biosynthetic Insights of Calyculin- and Misakinolide-Type Compounds in "Candidatus Entotheonella sp."

Diastereoselective Total Synthesis and Structural Confirmation of Surugamide F

The Revised Structure of the Cyclic Octapeptide Surugamide A

Scrobiculosides A and B from the deep-sea sponge Pachastrella scrobiculosa

Crystal Structures of Flavone C-Glycosides from Oolong Tea Leaves: Chafuroside A Dihydrate and Chafuroside B Monohydrate

Furan fatty acid as an anti-inflammatory component from the green-lipped mussel Perna canaliculus

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