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A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish

Nature protocols, 2016-12, Vol.11 (12), p.2357-2375

2016

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Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease

The New England journal of medicine, 2020-12, Vol.383 (27), p.2628-2638

2020

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High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9

Genome research, 2015-07, Vol.25 (7), p.1030

2015

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Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability

Disease models & mechanisms, 2021-11, Vol.14 (11)

2021

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Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10668

2022

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Novel degenerative and developmental defects in a zebrafish model of mucolipidosis type IV

Human molecular genetics, 2017-07, Vol.26 (14), p.2701-2718

2017

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Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors

Annals of the rheumatic diseases, 2018-04, Vol.77 (4), p.612

2018

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A large-scale zebrafish gene knockout resource for the genome-wide study of gene function

Genome research, 2013-04, Vol.23 (4), p.727

2013

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Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform for in vivo screening of candidate therapeutic compounds

Disease models & mechanisms, 2018-09, Vol.11 (9)

2018

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Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephaly

Molecular genetics and metabolism, 2009-10, Vol.98 (1), p.225-234

2009

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Identification of the Putative Staphylococcal AgrB Catalytic Residues Involving the Proteolytic Cleavage of AgrD to Generate Autoinducing Peptide

The Journal of biological chemistry, 2005-04, Vol.280 (17), p.16695-16704

2005

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A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation

npj Regenerative medicine, 2020, Vol.5 (1), p.6-6, Article 6

2020

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Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration

Frontiers in cell and developmental biology, 2018-08, Vol.6, p.88-88

2018

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Loss of Mgat5a-mediated N-glycosylation stimulates regeneration in zebrafish

Cell regeneration, 2016-10, Vol.5 (1), p.3-3, Article 5:3

2016

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Microinjection in Zebrafish for Genome Editing and Functional Studies

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1874, p.459

2019

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Staphylococcus intermedius Produces a Functional agr Autoinducing Peptide Containing a Cyclic Lactone

Journal of Bacteriology, 2005-05, Vol.187 (9), p.3139-3150

2005

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Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

The New England journal of medicine, 2014-03, Vol.370 (10), p.911-920

2014

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Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia

Developmental biology, 2009-02, Vol.326 (1), p.201-211

2009

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Zrsr2 Deficient Zebrafish Display Hematopoietic Defects and U12-Type Intron Retention in mRNA Processing Genes

Blood, 2020-11, Vol.136 (Supplement 1), p.32-32

2020

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Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage

Human molecular genetics, 2019-12, Vol.28 (24), p.4173-4185

2019

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Novel degenerative and developmental defects in a zebrafish model of mucolipidosis type IV

Human molecular genetics, 2017-07, Vol.26 (14), p.2701-2718

2017

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CRISPRz: a database of zebrafish validated sgRNAs

Nucleic acids research, 2016-01, Vol.44 (D1), p.D822

2016

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Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseases

Scientific reports, 2016-07, Vol.6 (1), p.29946-29946, Article 29946

2016

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Extracellular HSP60 triggers tissue regeneration and wound healing by regulating inflammation and cell proliferation

npj Regenerative medicine, 2016-10, Vol.1 (1), p.16013, Article 16013

2016

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A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation

npj Regenerative medicine, 2020-03, Vol.5 (1), p.6

2020

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A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish

Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9

Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability

Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish

Novel degenerative and developmental defects in a zebrafish model of mucolipidosis type IV

Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors

A large-scale zebrafish gene knockout resource for the genome-wide study of gene function

Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform for in vivo screening of candidate therapeutic compounds

Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephaly

Identification of the Putative Staphylococcal AgrB Catalytic Residues Involving the Proteolytic Cleavage of AgrD to Generate Autoinducing Peptide

A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation

Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration

Loss of Mgat5a-mediated N-glycosylation stimulates regeneration in zebrafish

Microinjection in Zebrafish for Genome Editing and Functional Studies

Staphylococcus intermedius Produces a Functional agr Autoinducing Peptide Containing a Cyclic Lactone

Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia

Zrsr2 Deficient Zebrafish Display Hematopoietic Defects and U12-Type Intron Retention in mRNA Processing Genes

Splicing factor DHX15 affects tp53 and mdm2 expression via alternate splicing and promoter usage

Novel degenerative and developmental defects in a zebrafish model of mucolipidosis type IV

CRISPRz: a database of zebrafish validated sgRNAs

Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseases

Extracellular HSP60 triggers tissue regeneration and wound healing by regulating inflammation and cell proliferation

A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation

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