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Targeting MET in cancer: rationale and progress

Nature reviews. Cancer, 2012-02, Vol.12 (2), p.89-103

2012

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Novel Therapeutic Inhibitors of the c-Met Signaling Pathway in Cancer

Clinical cancer research, 2009-04, Vol.15 (7), p.2207-2214

2009

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Chromosome instability drives phenotypic switching to metastasis

Proceedings of the National Academy of Sciences - PNAS, 2016-12, Vol.113 (51), p.14793-14798

2016

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Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2590-2595

2014

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Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (2), p.570-575

2012

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Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation

PloS one, 2012-06, Vol.7 (6), p.e38955

2012

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Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (31), p.12909-12914

2009

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Hepatocyte Growth Factor/Scatter Factor Mediates Angiogenesis through Positive VEGF and Negative Thrombospondin 1 Regulation

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (22), p.12718-12723

2003

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Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (32), p.E2987-E2996

2013

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Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (21), p.8677-8682

2009

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Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (21), p.8995-9000

2007

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Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

Cancer cell, 2011-07, Vol.20 (1), p.92-103

2011

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MET4 expression predicts poor prognosis of gastric cancers with Helicobacter pylori infection

Cancer science, 2017-03, Vol.108 (3), p.322-330

2017

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Proliferation and Invasion: Plasticity in Tumor Cells

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (30), p.10528-10533

2005

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Structural basis for agonism and antagonism of hepatocyte growth factor

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (30), p.13264-13269

2010

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Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor

Science (American Association for the Advancement of Science), 1998-05, Vol.280 (5364), p.734-737

1998

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c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion

Cancer research (Chicago, Ill.), 2007-02, Vol.67 (4), p.1670-1679

2007

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Abnormal Centrosome Amplification in the Absence of p53

Science (American Association for the Advancement of Science), 1996-03, Vol.271 (5256), p.1744-1747

1996

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HGF/SF-met signaling in the control of branching morphogenesis and invasion

Journal of cellular biochemistry, 2003-02, Vol.88 (2), p.408-417

2003

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Met receptor tyrosine kinase: enhanced signaling through adapter proteins

Oncogene, 2000-11, Vol.19 (49), p.5582-5589

2000

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MET Kinase Inhibitor SGX523 Synergizes with Epidermal Growth Factor Receptor Inhibitor Erlotinib in a Hepatocyte Growth Factor―Dependent Fashion to Suppress Carcinoma Growth

Cancer research (Chicago, Ill.), 2010-09, Vol.70 (17), p.6880-6890

2010

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Overexpression of sprouty 2 inhibits HGF SF-mediated cell growth, invasion, migration, and cytokinesis

Oncogene, 2004-07, Vol.23 (30), p.5193-5202

2004

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HGF／SF-Met signaling in tumor progression

Cell research, 2005, Vol.15 (1), p.49-51

2005

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A novel germ line juxtamembrane Met mutation in human gastric cancer

Oncogene, 2000-10, Vol.19 (43), p.4947-4953

2000

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Hepatocyte Growth Factor Promotes Cancer Cell Migration and Angiogenic Factors Expression: A Prognostic Marker of Human Esophageal Squamous Cell Carcinomas

Clinical cancer research, 2005-09, Vol.11 (17), p.6190-6197

2005

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Targeting MET in cancer: rationale and progress

Novel Therapeutic Inhibitors of the c-Met Signaling Pathway in Cancer

Chromosome instability drives phenotypic switching to metastasis

Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation

Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation

Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer

Hepatocyte Growth Factor/Scatter Factor Mediates Angiogenesis through Positive VEGF and Negative Thrombospondin 1 Regulation

Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent

Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease

Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

MET4 expression predicts poor prognosis of gastric cancers with Helicobacter pylori infection

Proliferation and Invasion: Plasticity in Tumor Cells

Structural basis for agonism and antagonism of hepatocyte growth factor

Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor

c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion

Abnormal Centrosome Amplification in the Absence of p53

HGF/SF-met signaling in the control of branching morphogenesis and invasion

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

MET Kinase Inhibitor SGX523 Synergizes with Epidermal Growth Factor Receptor Inhibitor Erlotinib in a Hepatocyte Growth Factor―Dependent Fashion to Suppress Carcinoma Growth

Overexpression of sprouty 2 inhibits HGF SF-mediated cell growth, invasion, migration, and cytokinesis

HGF／SF-Met signaling in tumor progression

A novel germ line juxtamembrane Met mutation in human gastric cancer

Hepatocyte Growth Factor Promotes Cancer Cell Migration and Angiogenic Factors Expression: A Prognostic Marker of Human Esophageal Squamous Cell Carcinomas

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