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Diagnosis and predictors of sessile serrated adenoma after educational training in a large, community-based, integrated healthcare setting

Gastrointestinal endoscopy, 2018-03, Vol.87 (3), p.755-765.e1

2018

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EXEL-7647 Inhibits Mutant Forms of ErbB2 Associated with Lapatinib Resistance and Neoplastic Transformation

Clinical cancer research, 2008-04, Vol.14 (8), p.2465-2475

2008

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Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-( N, N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (8), p.2179-2185

2009

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The use of computational methods in the discovery and design of kinase inhibitors

Current pharmaceutical design, 2002-01, Vol.8 (17), p.1527-1545

2002

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Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 6. The Development of Predictive In Vitro Potency Models Using CoMFA and HQSAR Methodologies

Journal of medicinal chemistry, 2002-01, Vol.45 (2), p.292-303

2002

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Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2218-2234

2013

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Oligomeric flavanoids. Part 34: Doubly-linked proteracacinidin analogues from Acacia caffra and Acacia galpinii

Tetrahedron, 2001-01, Vol.57 (4), p.661-667

2001

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Design, synthesis and structure–Activity relationships of benzoxazinone-Based factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (3), p.561-566

2003

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Design, synthesis and biological activity of novel non-amidine factor Xa inhibitors. Part 1: P1 Structure-activity relationships of the substituted 1-(2-naphthyl)-1H-pyrazole-5-carboxylamides

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1651-1655

2002

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SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7653-7658

2012

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Discovery of a Novel Class of Potent and Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists

Journal of medicinal chemistry, 2012-02, Vol.55 (3), p.1368-1381

2012

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1-(2-Naphthyl)-1 H -pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 3: Design, synthesis and SAR of orally bioavailable benzamidine-P4 inhibitors

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1229-1234

2004

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1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor xa inhibitors. Part 3: Design, synthesis and sar of orally bioavailable benzamidine-P4 inhibitors

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1229-1234

2004

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Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido )-5-metho xybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (8), p.2179-2185

2009

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Design, synthesis, and structure–Activity relationships of substituted piperazinone-Based transition state factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (4), p.729-732

2003

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Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors with improved functional activity

Bioorganic & medicinal chemistry letters, 2004-02, Vol.14 (4), p.989-993

2004

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N, N-Dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as potent factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2073-2078

2004

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Design, synthesis, and SAR of monobenzamidines and aminoisoquinolines as factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1657-1661

2002

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Parallel synthesis and structure–activity relationships of a series of highly potent, selective, and neutral factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (15), p.4045-4050

2004

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Comparison of 3D quantitative structure-activity relationship methods: analysis of the in vitro antimalarial activity of 154 artemisinin analogues by hypothetical active-site lattice and comparative molecular field analysis

Journal of computer-aided molecular design, 1998-03, Vol.12 (2), p.165-181

1998

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Design, synthesis, and SAR of substituted acrylamides as factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (11), p.1511-1515

2002

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Design, Synthesis, and SAR of Amino Acid Derivatives as Factor Xa Inhibitors

Bioorganic & medicinal chemistry letters, 2001-11, Vol.11 (22), p.2947-2950

2001

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Design and synthesis of glycolic and mandelic acid derivatives as factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (17), p.2279-2282

2001

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A highly integrated CMOS zero-IF transmitter for cellular CDMA applications

2005 IEEE Radio Frequency integrated Circuits (RFIC) Symposium - Digest of Papers, 2005, p.17-20

2005

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Design, synthesis and biological activity of novel non-amidine factor Xa inhibitors. Part 1: P(1) structure-activity relationships of the substituted 1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1651-1655

2002

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Diagnosis and predictors of sessile serrated adenoma after educational training in a large, community-based, integrated healthcare setting

EXEL-7647 Inhibits Mutant Forms of ErbB2 Associated with Lapatinib Resistance and Neoplastic Transformation

Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-( N, N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor

The use of computational methods in the discovery and design of kinase inhibitors

Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 6. The Development of Predictive In Vitro Potency Models Using CoMFA and HQSAR Methodologies

Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)

Oligomeric flavanoids. Part 34: Doubly-linked proteracacinidin analogues from Acacia caffra and Acacia galpinii

Design, synthesis and structure–Activity relationships of benzoxazinone-Based factor Xa inhibitors

Design, synthesis and biological activity of novel non-amidine factor Xa inhibitors. Part 1: P1 Structure-activity relationships of the substituted 1-(2-naphthyl)-1H-pyrazole-5-carboxylamides

SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors

Discovery of a Novel Class of Potent and Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists

1-(2-Naphthyl)-1 H -pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 3: Design, synthesis and SAR of orally bioavailable benzamidine-P4 inhibitors

1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor xa inhibitors. Part 3: Design, synthesis and sar of orally bioavailable benzamidine-P4 inhibitors

Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido )-5-metho xybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor

Design, synthesis, and structure–Activity relationships of substituted piperazinone-Based transition state factor Xa inhibitors

Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors with improved functional activity

N, N-Dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as potent factor Xa inhibitors

Design, synthesis, and SAR of monobenzamidines and aminoisoquinolines as factor Xa inhibitors

Parallel synthesis and structure–activity relationships of a series of highly potent, selective, and neutral factor Xa inhibitors

Comparison of 3D quantitative structure-activity relationship methods: analysis of the in vitro antimalarial activity of 154 artemisinin analogues by hypothetical active-site lattice and comparative molecular field analysis

Design, synthesis, and SAR of substituted acrylamides as factor Xa inhibitors

Design, Synthesis, and SAR of Amino Acid Derivatives as Factor Xa Inhibitors

Design and synthesis of glycolic and mandelic acid derivatives as factor Xa inhibitors

A highly integrated CMOS zero-IF transmitter for cellular CDMA applications

Design, synthesis and biological activity of novel non-amidine factor Xa inhibitors. Part 1: P(1) structure-activity relationships of the substituted 1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides

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