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Opportunities in somatostatin research: biological, chemical and therapeutic aspects

Nature reviews. Drug discovery, 2003-12, Vol.2 (12), p.999-1017

2003

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SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile

European journal of endocrinology, 2002-05, Vol.146 (5), p.707-716

2002

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Regulation of CRH-induced secretion of ACTH and corticosterone by SOM230 in rats

European journal of endocrinology, 2005-09, Vol.153 (3), p.R7-R10

2005

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Drug design at peptide receptors: somatostatin receptor ligands

Journal of molecular neuroscience, 2002-02, Vol.18 (1-2), p.15-27

2002

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Biochemical pharmacology and analysis of fluoropyrimidines alone and in combination with modulators

Pharmacology & therapeutics (Oxford), 1991, Vol.50 (3), p.367-424

Weckbecker, Gisbert

1991

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Binding properties of somatostatin receptor subtypes

Metabolism, clinical and experimental, 1996-08, Vol.45 (8 Suppl 1), p.17-20

1996

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SOM230: A New Somatostatin Peptidomimetic with Potent Inhibitory Effects on the Growth Hormone/Insulin-Like Growth Factor-I Axis in Rats, Primates, and Dogs

Endocrinology (Philadelphia), 2002-10, Vol.143 (10), p.4123-4130

2002

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Somatostatin analogue octreotide enhances the antineoplastic effects of tamoxifen and ovariectomy on 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinomas

Cancer research (Chicago, Ill.), 1994-12, Vol.54 (24), p.6334-6337

1994

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Experimental heart transplantation: effect of cyclosporine on expression and activity of metzincins

Swiss medical weekly, 2009-04

2009

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The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5

European journal of endocrinology, 2005-04, Vol.152 (4), p.645-654

2005

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Aromatic Quinolinecarboxamides as Selective, Orally Active Antibody Production Inhibitors for Prevention of Acute Xenograft Rejection

Journal of medicinal chemistry, 2001-06, Vol.44 (12), p.1986-1992

2001

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A Novel Somatostatin Mimic with Broad Somatotropin Release Inhibitory Factor Receptor Binding and Superior Therapeutic Potential

Journal of medicinal chemistry, 2003-06, Vol.46 (12), p.2334-2344

2003

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New insights on SOM230, a universal somatostatin receptor ligand

Journal of endocrinological investigation, 2003, Vol.26 (8 Suppl), p.14

2003

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The Novel Somatostatin Analog SOM230 Is a Potent Inhibitor of Hormone Release by Growth Hormone- and Prolactin-Secreting Pituitary Adenomas in Vitro

The journal of clinical endocrinology and metabolism, 2004-04, Vol.89 (4), p.1577-1585

2004

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A Single-Dose Comparison of the Acute Effects between the New Somatostatin Analog SOM230 and Octreotide in Acromegalic Patients

The journal of clinical endocrinology and metabolism, 2004-02, Vol.89 (2), p.638-645

2004

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SDZ RAD inhibits cold ischemia-induced vascular remodeling

Transplantation proceedings, 1999-02, Vol.31 (1-2), p.1024-1025

1999

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The Novel Somatostatin Ligand (SOM230) Regulates Human and Rat Anterior Pituitary Hormone Secretion

The journal of clinical endocrinology and metabolism, 2004-06, Vol.89 (6), p.3027-3032

2004

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

Journal of molecular biology, 2008-07, Vol.380 (5), p.828-843

2008

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Potentiation of the anti-proliferative effects of anti-cancer drugs by octreotide in vitro and in vivo

Digestion, 1996, Vol.57 Suppl 1 (1), p.22-28

1996

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Somatostatin analogues for somatostatin-receptor-mediated radiotherapy of cancer

Digestion, 1996, Vol.57 Suppl 1 (1), p.17-21

1996

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1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (4), p.1217-1220

2005

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Preclinical studies on the anticancer activity of the somatostatin analogue octreotide (SMS 201-995)

Metabolism, clinical and experimental, 1992-09, Vol.41 (9), p.99-103

1992

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The somatostatin receptor-targeted radiotherapeutic [90Y-DOTA-DPhe1, Tyr3]octreotide (90Y-SMT 487) eradicates experimental rat pancreatic CA 20948 tumours

European journal of nuclear medicine, 1998-07, Vol.25 (7), p.668-674

1998

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Indirect antiproliferative effect of the somatostatin analog octreotide on MIA PaCa-2 human pancreatic carcinoma in nude mice

The Yale journal of biology & medicine, 1997-09, Vol.70 (5-6), p.549-554

1997

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Orally Bioavailable Competitive CCR5 Antagonists

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.1939-1955

2004

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Opportunities in somatostatin research: biological, chemical and therapeutic aspects

SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile

Regulation of CRH-induced secretion of ACTH and corticosterone by SOM230 in rats

Drug design at peptide receptors: somatostatin receptor ligands

Biochemical pharmacology and analysis of fluoropyrimidines alone and in combination with modulators

Binding properties of somatostatin receptor subtypes

SOM230: A New Somatostatin Peptidomimetic with Potent Inhibitory Effects on the Growth Hormone/Insulin-Like Growth Factor-I Axis in Rats, Primates, and Dogs

Somatostatin analogue octreotide enhances the antineoplastic effects of tamoxifen and ovariectomy on 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinomas

Experimental heart transplantation: effect of cyclosporine on expression and activity of metzincins

The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5

Aromatic Quinolinecarboxamides as Selective, Orally Active Antibody Production Inhibitors for Prevention of Acute Xenograft Rejection

A Novel Somatostatin Mimic with Broad Somatotropin Release Inhibitory Factor Receptor Binding and Superior Therapeutic Potential

New insights on SOM230, a universal somatostatin receptor ligand

The Novel Somatostatin Analog SOM230 Is a Potent Inhibitor of Hormone Release by Growth Hormone- and Prolactin-Secreting Pituitary Adenomas in Vitro

A Single-Dose Comparison of the Acute Effects between the New Somatostatin Analog SOM230 and Octreotide in Acromegalic Patients

SDZ RAD inhibits cold ischemia-induced vascular remodeling

The Novel Somatostatin Ligand (SOM230) Regulates Human and Rat Anterior Pituitary Hormone Secretion

Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

Potentiation of the anti-proliferative effects of anti-cancer drugs by octreotide in vitro and in vivo

Somatostatin analogues for somatostatin-receptor-mediated radiotherapy of cancer

1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1

Preclinical studies on the anticancer activity of the somatostatin analogue octreotide (SMS 201-995)

The somatostatin receptor-targeted radiotherapeutic [90Y-DOTA-DPhe1, Tyr3]octreotide (90Y-SMT 487) eradicates experimental rat pancreatic CA 20948 tumours

Indirect antiproliferative effect of the somatostatin analog octreotide on MIA PaCa-2 human pancreatic carcinoma in nude mice

Orally Bioavailable Competitive CCR5 Antagonists

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