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Immunogenicity of pembrolizumab in patients with advanced tumors

Journal for immunotherapy of cancer, 2019-08, Vol.7 (1), p.212-212, Article 212

2019

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Literature mining for the discovery of hidden connections between drugs, genes and diseases

PLoS computational biology, 2010-09, Vol.6 (9), p.e1000943-136

2010

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Pharmacokinetics and Pharmacodynamics of the BACE1 Inhibitor Verubecestat (MK‐8931) in Healthy Japanese Adults: A Randomized, Placebo‐Controlled Study

Clinical pharmacology and therapeutics, 2019-05, Vol.105 (5), p.1234-1243

2019

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Tildrakizumab, a novel anti-IL-23 monoclonal antibody, is unaffected by ethnic variability in Caucasian, Chinese, and Japanese subjects

International journal of clinical pharmacology and therapeutics, 2015-02, Vol.53 (2), p.139-146

2015

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Immunogenicity of pembrolizumab (pembro) in patients (pts) with advanced melanoma (MEL) and non-small cell lung cancer (NSCLC): Pooled results from KEYNOTE-001, 002, 006, and 010

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.3063-3063

2016

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Pharmacokinetics and Pharmacodynamics of the BACE 1 Inhibitor Verubecestat ( MK ‐8931) in Healthy Japanese Adults: A Randomized, Placebo‐Controlled Study

Clinical pharmacology and therapeutics, 2019-05, Vol.105 (5), p.1234-1243

2019

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Superagonistic Activation of ErbB-1 by EGF-related Growth Factors with Enhanced Association and Dissociation Rate Constants

The Journal of biological chemistry, 2000-09, Vol.275 (35), p.26748

Lenferink, A. E.G.

2000

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Insertion of Argos Sequences into the B-Loop of Epidermal Growth Factor Results in a Low-Affinity Ligand with Strong Agonistic Activity

Biochemistry (Easton), 1997-06, Vol.36 (24), p.7425-7431

1997

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Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers

The EMBO journal, 1998-06, Vol.17 (12), p.3385-3397

1998

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Population pharmacokinetic (popPK) model of pembrolizumab (pembro; MK-3475) in patients (pts) treated in KEYNOTE-001 and KEYNOTE-002

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.3058-3058

2015

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A rationale for carboplatin treatment and abdominal hyperthermia in cancers restricted to the peritoneal cavity

Cancer research (Chicago, Ill.), 1992-03, Vol.52 (5), p.1252-1258

1992

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Superagonistic behaviour of epidermal growth factor/transforming growth factor-alpha chimaeras: correlation with receptor routing after ligand-induced internalization

Biochemical journal, 1997-11, Vol.327 ( Pt 3) (3), p.859-865

1997

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Literature Mining for the Discovery of Hidden Connections between Drugs, Genes and Diseases: e1000943

PLoS computational biology, 2010-09, Vol.6 (9)

2010

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Insertion of Argos Sequences into the B-Loop of Epidermal Growth Factor Results in a Low-Affinity Ligand with Strong Agonistic Activity

Biochemistry (Easton), 1997-09, Vol.36 (38), p.11542-11542

1997

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Identification of the Minimal Requirements for Binding to the Human Epidermal Growth Factor (EGF) Receptor Using Chimeras of Human EGF and an EGF Repeat of Drosophila Notch

The Journal of biological chemistry, 1998-06, Vol.273 (26), p.16075-16081

1998

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A Single Amino Acid Exchange, Arg-45 to Ala, Generates an Epidermal Growth Factor (EGF) Mutant with High Affinity for the Chicken EGF Receptor (∗)

The Journal of biological chemistry, 1995-09, Vol.270 (38), p.22337-22343

1995

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Superagonistic activation of ErbB-1 by EGF-related growth factors with enhanced association and dissociation rate constants

The Journal of biological chemistry, 2000-09, Vol.275 (35), p.26748-26753

2000

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Effects of temperature on the interaction of cisplatin and carboplatin with cellular DNA

Biochemical pharmacology, 1993-10, Vol.46 (7), p.1229-1237

1993

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Non-linear antigenic regions in epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) studied by EGF-TGF alpha chimaeras

Biochemical journal, 2000-07, Vol.349 (Pt 1), p.267-274

2000

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Non-linear antigenic regions in epidermal growth factor (EGF) and transforming growth factor α (TGFα) studied by EGF–TGFα chimaeras

Biochemical journal, 2000-07, Vol.349 (1), p.267-274

2000

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Combination treatment of cis- and carboplatin in cancers restricted to the peritoneal cavity in the rat

Cancer chemotherapy and pharmacology, 1993-11, Vol.32 (6), p.425-433

1993

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The influence of hyperthermia on the uptake of cisplatin in the rat cervical spinal cord

European journal of cancer (1990), 1992-01, Vol.28 (6), p.1139-1143

1992

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Are Structural Analogues to Bisphenol A Safe Alternatives?

Toxicological sciences, 2014-05, Vol.139 (1), p.35-47

2014

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An effect-directed strategy for characterizing emerging chemicals in food contact materials made from paper and board

Food and chemical toxicology, 2017-08, Vol.106 (Pt A), p.250-259

2017

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Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors

Molecular oncology, 2013-06, Vol.7 (3), p.669-679

2013

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Immunogenicity of pembrolizumab in patients with advanced tumors

Literature mining for the discovery of hidden connections between drugs, genes and diseases

Pharmacokinetics and Pharmacodynamics of the BACE1 Inhibitor Verubecestat (MK‐8931) in Healthy Japanese Adults: A Randomized, Placebo‐Controlled Study

Tildrakizumab, a novel anti-IL-23 monoclonal antibody, is unaffected by ethnic variability in Caucasian, Chinese, and Japanese subjects

Immunogenicity of pembrolizumab (pembro) in patients (pts) with advanced melanoma (MEL) and non-small cell lung cancer (NSCLC): Pooled results from KEYNOTE-001, 002, 006, and 010

Pharmacokinetics and Pharmacodynamics of the BACE 1 Inhibitor Verubecestat ( MK ‐8931) in Healthy Japanese Adults: A Randomized, Placebo‐Controlled Study

Superagonistic Activation of ErbB-1 by EGF-related Growth Factors with Enhanced Association and Dissociation Rate Constants

Insertion of Argos Sequences into the B-Loop of Epidermal Growth Factor Results in a Low-Affinity Ligand with Strong Agonistic Activity

Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers

Population pharmacokinetic (popPK) model of pembrolizumab (pembro; MK-3475) in patients (pts) treated in KEYNOTE-001 and KEYNOTE-002

A rationale for carboplatin treatment and abdominal hyperthermia in cancers restricted to the peritoneal cavity

Superagonistic behaviour of epidermal growth factor/transforming growth factor-alpha chimaeras: correlation with receptor routing after ligand-induced internalization

Literature Mining for the Discovery of Hidden Connections between Drugs, Genes and Diseases: e1000943

Insertion of Argos Sequences into the B-Loop of Epidermal Growth Factor Results in a Low-Affinity Ligand with Strong Agonistic Activity

Identification of the Minimal Requirements for Binding to the Human Epidermal Growth Factor (EGF) Receptor Using Chimeras of Human EGF and an EGF Repeat of Drosophila Notch

A Single Amino Acid Exchange, Arg-45 to Ala, Generates an Epidermal Growth Factor (EGF) Mutant with High Affinity for the Chicken EGF Receptor (∗)

Superagonistic activation of ErbB-1 by EGF-related growth factors with enhanced association and dissociation rate constants

Effects of temperature on the interaction of cisplatin and carboplatin with cellular DNA

Non-linear antigenic regions in epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) studied by EGF-TGF alpha chimaeras

Non-linear antigenic regions in epidermal growth factor (EGF) and transforming growth factor α (TGFα) studied by EGF–TGFα chimaeras

Combination treatment of cis- and carboplatin in cancers restricted to the peritoneal cavity in the rat

The influence of hyperthermia on the uptake of cisplatin in the rat cervical spinal cord

Are Structural Analogues to Bisphenol A Safe Alternatives?

An effect-directed strategy for characterizing emerging chemicals in food contact materials made from paper and board

Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors

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