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Spontaneous and optogenetically induced cortical spreading depolarization in familial hemiplegic migraine type 1 mutant mice

Neurobiology of disease, 2024-03, Vol.192, p.106405-106405, Article 106405

2024

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Optogenetic induction of cortical spreading depression in anesthetized and freely behaving mice

Journal of cerebral blood flow and metabolism, 2017-05, Vol.37 (5), p.1641-1655

2017

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MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells

Scientific reports, 2015-07, Vol.5 (1), p.12448-12448, Article 12448

2015

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Pharmacokinetics of Clindamycin in Pregnant Women in the Peripartum Period

Antimicrobial Agents and Chemotherapy, 2010-05, Vol.54 (5), p.2175-2181

2010

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Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([18F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression

EJNMMI radiopharmacy and chemistry, 2018-12, Vol.3 (1), p.11-11, Article 11

2018

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Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice

Brain (London, England : 1878), 2019-02, Vol.142 (2), p.412-425

2019

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(R)-[11C]verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus

BMC medical imaging, 2011-01, Vol.11 (1), p.1-1, Article 1

2011

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Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research

Trends in pharmacological sciences (Regular ed.), 2008-04, Vol.29 (4), p.186-191

2008

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Changes in GABAA receptor properties in amygdala kindled animals: In vivo studies using [11C]flumazenil and positron emission tomography

Epilepsia (Copenhagen), 2009-01, Vol.50 (1), p.88-98

2009

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Spontaneous spreading depolarizations originate subcortically in a novel mouse model of familial hemiplegic migraine type 2

Neurobiology of disease, 2024-11, Vol.202, p.106714, Article 106714

2024

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Pharmacokinetics of Amoxicillin in Maternal, Umbilical Cord, and Neonatal Sera

Antimicrobial Agents and Chemotherapy, 2009-04, Vol.53 (4), p.1574-1580

2009

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[11C]phenytoin revisited: synthesis by [11C]CO carbonylation and first evaluation as a P-gp tracer in rats

EJNMMI research, 2012-01, Vol.2 (1), p.36-36

2012

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Apnea Associated with Brainstem Seizures in Cacna1a S218L Mice Is Caused by Medullary Spreading Depolarization

The Journal of neuroscience, 2019-11, Vol.39 (48), p.9633-9644

2019

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Apnea Associated with Brainstem Seizures in Cacna1aS218L Mice Is Caused by Medullary Spreading Depolarization

The Journal of neuroscience, 2019-11, Vol.39 (48), p.9633-9644

2019

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Impaired θ-γ Coupling Indicates Inhibitory Dysfunction and Seizure Risk in a Dravet Syndrome Mouse Model

The Journal of neuroscience, 2021-01, Vol.41 (3), p.524-537

2021

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Biomarkers in epilepsy–A modelling perspective

European journal of pharmaceutical sciences, 2017-11, Vol.109, p.S47-S52

2017

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Mechanism-based pharmacokinetic -pharmacodynamic modeling : Biophase distribution, receptor theory, and dynamical systems analysis

Annual review of pharmacology and toxicology, 2007-01, Vol.47 (1), p.357-400

2007

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Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes

American journal of obstetrics and gynecology, 2008, Vol.198 (1), p.108.e1-108.e6

2008

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(R)-[11C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: Evaluation in a rat epilepsy model

Neuropharmacology, 2014-10, Vol.85, p.104-112

2014

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Pharmacodynamic Analysis of the Anticonvulsant Effects of Tiagabine and Lamotrigine in Combination in the Rat

Epilepsia (Copenhagen), 2004-05, Vol.45 (5), p.424-435

2004

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Parametric Methods for Dynamic 11C-Phenytoin PET Studies

The Journal of nuclear medicine (1978), 2017-03, Vol.58 (3), p.479-483

2017

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Towards a mechanism-based analysis of pharmacodynamic drug-drug interactions in vivo

Pharmacology & therapeutics (Oxford), 2005-04, Vol.106 (1), p.1-18

2005

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Altered GABA A receptor density and unaltered blood–brain barrier [ 11 C]flumazenil transport in drug-resistant epilepsy patients with mesial temporal sclerosis

Journal of cerebral blood flow and metabolism, 2017-01, Vol.37 (1), p.97-105

2017

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Synergistic Combinations of Anticonvulsant Agents: What Is the Evidence from Animal Experiments?

Epilepsia (Copenhagen), 2007-03, Vol.48 (3), p.412-434

2007

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Parametric Methods for Dynamic 11 C-Phenytoin PET Studies

Journal of Nuclear Medicine, 2017-03, Vol.58 (3), p.479-483

2017

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Spontaneous and optogenetically induced cortical spreading depolarization in familial hemiplegic migraine type 1 mutant mice

Optogenetic induction of cortical spreading depression in anesthetized and freely behaving mice

MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells

Pharmacokinetics of Clindamycin in Pregnant Women in the Peripartum Period

Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([18F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression

Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice

(R)-[11C]verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus

Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research

Changes in GABAA receptor properties in amygdala kindled animals: In vivo studies using [11C]flumazenil and positron emission tomography

Spontaneous spreading depolarizations originate subcortically in a novel mouse model of familial hemiplegic migraine type 2

Pharmacokinetics of Amoxicillin in Maternal, Umbilical Cord, and Neonatal Sera

[11C]phenytoin revisited: synthesis by [11C]CO carbonylation and first evaluation as a P-gp tracer in rats

Apnea Associated with Brainstem Seizures in Cacna1a S218L Mice Is Caused by Medullary Spreading Depolarization

Apnea Associated with Brainstem Seizures in Cacna1aS218L Mice Is Caused by Medullary Spreading Depolarization

Impaired θ-γ Coupling Indicates Inhibitory Dysfunction and Seizure Risk in a Dravet Syndrome Mouse Model

Biomarkers in epilepsy–A modelling perspective

Mechanism-based pharmacokinetic -pharmacodynamic modeling : Biophase distribution, receptor theory, and dynamical systems analysis

Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes

(R)-[11C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: Evaluation in a rat epilepsy model

Pharmacodynamic Analysis of the Anticonvulsant Effects of Tiagabine and Lamotrigine in Combination in the Rat

Parametric Methods for Dynamic 11C-Phenytoin PET Studies

Towards a mechanism-based analysis of pharmacodynamic drug-drug interactions in vivo

Altered GABA A receptor density and unaltered blood–brain barrier [ 11 C]flumazenil transport in drug-resistant epilepsy patients with mesial temporal sclerosis

Synergistic Combinations of Anticonvulsant Agents: What Is the Evidence from Animal Experiments?

Parametric Methods for Dynamic 11 C-Phenytoin PET Studies

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