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2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: Resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

Bioorganic & medicinal chemistry, 2002-07, Vol.10 (7), p.2259-2266

2002

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3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

Bioorganic & medicinal chemistry letters, 2015-08, Vol.25 (15), p.3024-3029

2015

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Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid

European journal of pharmacology, 2004-03, Vol.488 (1), p.101-109

2004

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Biostructural and Pharmacological Studies of Bicyclic Analogues of the 3-Isoxazolol Glutamate Receptor Agonist Ibotenic Acid

Journal of medicinal chemistry, 2010-12, Vol.53 (23), p.8354-8361

2010

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Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs

Organic & biomolecular chemistry, 2013-11, Vol.11 (43), p.7606-7610

2013

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Chemoenzymatic synthesis and in situ application of S-adenosyl-l-methionine analogsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3ob41702f

2013-10

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Convergent Synthesis and Pharmacology of Substituted Tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid Analogues

Journal of medicinal chemistry, 2005-05, Vol.48 (9), p.3438-3442

2005

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Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist

Bioorganic & medicinal chemistry, 2005-09, Vol.13 (17), p.5104-5112

2005

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Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist: Chemistry & Biology of Natural Products, Tetrahedron Prize for Creativity in Organic Chemistry 2004 K. Nakanishi

Bioorganic & medicinal chemistry, 2005, Vol.13 (17), p.5104-5112

2005

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Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile

Biochemical pharmacology, 2013-08, Vol.86 (4), p.521-528

2013

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Functional Characterization of Tet-AMPA [Tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic Acid] Analogues at Ionotropic Glutamate Receptors GluR1−GluR4. The Molecular Basis for the Functional Selectivity Profile of 2-Bn-Tet-AMPA

Journal of medicinal chemistry, 2007-08, Vol.50 (17), p.4177-4185

2007

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γ-Aminobutyric Acid and Glycine Neurotransmitter Transporters

Transporters As Drug Targets, 2017, p.69-106

2017

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GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (31), p.1-9

2021

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Identification of the First Highly Subtype-Selective Inhibitor of Human GABA Transporter GAT3

ACS chemical neuroscience, 2015-09, Vol.6 (9), p.1591-1599

2015

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The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity

Communications biology, 2020-12, Vol.3 (1), p.731-731, Article 731

2020

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The labeling of unsaturated [gamma]-hydroxybutyric acid by heavy isotopes of hydrogen: iridium complex-mediated H/D exchange by C--H bond activation vs reduction by boro-deuterides/tritides

Journal of labelled compounds & radiopharmaceuticals, 2016-10, Vol.59 (12), p.476

2016

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The labeling of unsaturated γ-hydroxybutyric acid by heavy isotopes of hydrogen: iridium complex-mediated H/D exchange by C─H bond activation vs reduction by boro-deuterides/tritides

Journal of labelled compounds & radiopharmaceuticals, 2016-10, Vol.59 (12), p.476-483

2016

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New Synthesis and Tritium Labeling of a Selective Ligand for Studying High-Affinity γ‑Hydroxybutyrate (GHB) Binding Sites

Journal of medicinal chemistry, 2013-10, Vol.56 (20), p.8201-8205

2013

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Pharmacological Identification of a Guanidine-Containing [beta]-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1)

Neurochemical research, 2014-10, Vol.39 (10), p.1988

2014

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Pharmacological Identification of a Guanidine-Containing β-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1)

Neurochemical research, 2014-10, Vol.39 (10), p.1988-1996

2014

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Polyamine toxins: development of selective ligands for ionotropic receptors

Toxicon (Oxford), 2005-03, Vol.45 (3), p.249-254

2005

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Preparation of 7-Substituted Ginkgolide Derivatives: Potent Platelet Activating Factor (PAF) Receptor Antagonists

Journal of medicinal chemistry, 2003-02, Vol.46 (4), p.601-608

2003

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Probing the Pharmacophore of Ginkgolides as Glycine Receptor Antagonists

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1610-1617

2007

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Radiosynthesis and Evaluation of [11C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ‑Hydroxybutyric Acid Binding Sites

ACS chemical neuroscience, 2017-01, Vol.8 (1), p.22-27

2017

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The Relationship between Agonist Potency and AMPA Receptor Kinetics

Biophysical journal, 2006-08, Vol.91 (4), p.1336-1346

2006

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2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: Resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid

Biostructural and Pharmacological Studies of Bicyclic Analogues of the 3-Isoxazolol Glutamate Receptor Agonist Ibotenic Acid

Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs

Chemoenzymatic synthesis and in situ application of S-adenosyl-l-methionine analogsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3ob41702f

Convergent Synthesis and Pharmacology of Substituted Tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid Analogues

Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist

Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist: Chemistry & Biology of Natural Products, Tetrahedron Prize for Creativity in Organic Chemistry 2004 K. Nakanishi

Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile

Functional Characterization of Tet-AMPA [Tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic Acid] Analogues at Ionotropic Glutamate Receptors GluR1−GluR4. The Molecular Basis for the Functional Selectivity Profile of 2-Bn-Tet-AMPA

γ-Aminobutyric Acid and Glycine Neurotransmitter Transporters

GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

Identification of the First Highly Subtype-Selective Inhibitor of Human GABA Transporter GAT3

The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity

The labeling of unsaturated [gamma]-hydroxybutyric acid by heavy isotopes of hydrogen: iridium complex-mediated H/D exchange by C--H bond activation vs reduction by boro-deuterides/tritides

The labeling of unsaturated γ-hydroxybutyric acid by heavy isotopes of hydrogen: iridium complex-mediated H/D exchange by C─H bond activation vs reduction by boro-deuterides/tritides

New Synthesis and Tritium Labeling of a Selective Ligand for Studying High-Affinity γ‑Hydroxybutyrate (GHB) Binding Sites

Pharmacological Identification of a Guanidine-Containing [beta]-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1)

Pharmacological Identification of a Guanidine-Containing β-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1)

Polyamine toxins: development of selective ligands for ionotropic receptors

Preparation of 7-Substituted Ginkgolide Derivatives: Potent Platelet Activating Factor (PAF) Receptor Antagonists

Probing the Pharmacophore of Ginkgolides as Glycine Receptor Antagonists

Radiosynthesis and Evaluation of [11C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ‑Hydroxybutyric Acid Binding Sites

The Relationship between Agonist Potency and AMPA Receptor Kinetics

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