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Pre-Clinical Diastolic Dysfunction

Journal of the American College of Cardiology, 2014-02, Vol.63 (5), p.407-416

2014

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Effects of the Janus Kinase Inhibitor, Tofacitinib, on Testicular Leydig Cell Hyperplasia and Adenoma in Rats, and on Prolactin Signaling in Cultured Primary Rat Leydig Cells

Toxicological sciences, 2017-01, Vol.155 (1), p.148-156

2017

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The natural history of preclinical diastolic dysfunction: a population-based study

Circulation. Heart failure, 2012-03, Vol.5 (2), p.144-151

2012

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Comparative pathophysiology, toxicology, and human cancer risk assessment of pharmaceutical-induced hibernoma

Toxicology and applied pharmacology, 2013-12, Vol.273 (3), p.456-463

2013

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RENAL DYSFUNCTION IS ASSOCIATED WITH THE PROGRESSION OF PRECLINICAL DIASTOLIC DYSFUNCTION (STAGE B) TO SYMPTOMATIC HEART FAILURE (STAGE C): A POPULATION-BASED STUDY

Journal of the American College of Cardiology, 2011-04, Vol.57 (14), p.E396-E396

Vogel, Mark W

2011

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Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats – Comparison of juvenile and adult responses

Regulatory toxicology and pharmacology, 2018-04, Vol.94, p.306-322

2018

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Cellular and functional actions of tofacitinib related to the pathophysiology of hibernoma development

Regulatory toxicology and pharmacology, 2017-12, Vol.91, p.93-102

2017

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Renal and Hematologic Comparative Effects of Dissociated Agonist of the Glucocorticoid Receptor and Prednisone in Dogs With and Without Food Restriction

International journal of toxicology, 2018-05, Vol.37 (3), p.223-233

2018

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Gastric Parietal Cell Atrophy and Depletion after Administration of a Sphingosine-1-Phosphate 1 Inhibitor

Toxicologic pathology, 2014-01, Vol.42 (1), p.118-123

2014

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Mechanistic Investigations of Test Article–Induced Pancreatic Toxicity at the Endocrine–Exocrine Interface in the Rat

Toxicologic pathology, 2014-01, Vol.42 (1), p.229-242

2014

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Evaluation of the Effects of Subchronic Oral Administration of n-Butyl Maleate in Sprague-Dawley Rats

Journal of Toxicology and Environmental Health, Part A, 2007-01, Vol.70 (12), p.1038-1045

2007

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Novel Natriuretic Peptides: New Compounds and New Approaches

Current heart failure reports, 2011-03, Vol.8 (1), p.22-27

2011

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The Natural History of Preclinical Diastolic Dysfunction: A Population Based Study

Journal of cardiac failure, 2010, Vol.16 (8), p.S83-S83

2010

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Preclinical Diastolic Dysfunction

Journal of the American College of Cardiology, 2013-11, Vol.63 (5), p.407-416

2013

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Development of Safety Qualification Thresholds and Their Use in Orally Inhaled and Nasal Drug Product Evaluation

Toxicological sciences, 2007-06, Vol.97 (2), p.226-236

2007

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Reversible and irreversible elongation of ischemic, infarcted, and healed myocardium in response to increases in preload and afterload

Circulation (New York, N.Y.), 1991-07, Vol.84 (1), p.387-399

1991

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Methylprednisolone Sodium Succinate Treatment in Global Ischemia of the Cat Isolated Heart

Journal of cardiovascular pharmacology, 1979-01, Vol.1 (1), p.53-68

1979

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Inhibition of Long-Chain Acylcarnitine Accumulation During Coronary Artery Occlusion Does Not Alter Infarct Size in Dogs

Journal of cardiovascular pharmacology, 1994-05, Vol.23 (5), p.826-832

1994

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Considerations for Toxicology Studies of Respiratory Drug Products

Regulatory toxicology and pharmacology, 1997-04, Vol.25 (2), p.189-193

1997

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The Development of Safety Thresholds for Leachables in Orally Inhaled and Nasal Drug Products

Leachables and Extractables Handbook, 2012, p.45-58

2012

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Acute Alterations in Left Ventricular Diastolic Chamber Stiffness: Role of the “Erectile” Effect of Coronary Arterial Pressure and Flow in Normal and Damaged Hearts

Circulation research, 1982-10, Vol.51 (4), p.465-478

1982

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Effects of Alloxan-Induced Diabetes on Ischemia-Reperfusion Injury in Rabbit Hearts

Circulation research, 1988-05, Vol.62 (5), p.975-982

1988

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Influence of Glucose and Insulin on the Exaggerated Diastolic and Systolic Dysfunction of Hypertrophied Rat Hearts During Hypoxia

Circulation research, 1990-02, Vol.66 (2), p.406-415

1990

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Comparison of acute alterations in left ventricular relaxation and diastolic chamber stiffness induced by hypoxia and ischemia. Role of myocardial oxygen supply-demand imbalance

The Journal of clinical investigation, 1981-07, Vol.68 (1), p.91-102

1981

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Effects of Reperfusion after Coronary Artery Occlusion on Post-infarction Scar Tissue

Circulation research, 1985-10, Vol.57 (4), p.562-577

1985

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Pre-Clinical Diastolic Dysfunction

Effects of the Janus Kinase Inhibitor, Tofacitinib, on Testicular Leydig Cell Hyperplasia and Adenoma in Rats, and on Prolactin Signaling in Cultured Primary Rat Leydig Cells

The natural history of preclinical diastolic dysfunction: a population-based study

Comparative pathophysiology, toxicology, and human cancer risk assessment of pharmaceutical-induced hibernoma

RENAL DYSFUNCTION IS ASSOCIATED WITH THE PROGRESSION OF PRECLINICAL DIASTOLIC DYSFUNCTION (STAGE B) TO SYMPTOMATIC HEART FAILURE (STAGE C): A POPULATION-BASED STUDY

Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats – Comparison of juvenile and adult responses

Cellular and functional actions of tofacitinib related to the pathophysiology of hibernoma development

Renal and Hematologic Comparative Effects of Dissociated Agonist of the Glucocorticoid Receptor and Prednisone in Dogs With and Without Food Restriction

Gastric Parietal Cell Atrophy and Depletion after Administration of a Sphingosine-1-Phosphate 1 Inhibitor

Mechanistic Investigations of Test Article–Induced Pancreatic Toxicity at the Endocrine–Exocrine Interface in the Rat

Evaluation of the Effects of Subchronic Oral Administration of n-Butyl Maleate in Sprague-Dawley Rats

Novel Natriuretic Peptides: New Compounds and New Approaches

The Natural History of Preclinical Diastolic Dysfunction: A Population Based Study

Preclinical Diastolic Dysfunction

Development of Safety Qualification Thresholds and Their Use in Orally Inhaled and Nasal Drug Product Evaluation

Reversible and irreversible elongation of ischemic, infarcted, and healed myocardium in response to increases in preload and afterload

Methylprednisolone Sodium Succinate Treatment in Global Ischemia of the Cat Isolated Heart

Inhibition of Long-Chain Acylcarnitine Accumulation During Coronary Artery Occlusion Does Not Alter Infarct Size in Dogs

Considerations for Toxicology Studies of Respiratory Drug Products

The Development of Safety Thresholds for Leachables in Orally Inhaled and Nasal Drug Products

Acute Alterations in Left Ventricular Diastolic Chamber Stiffness: Role of the “Erectile” Effect of Coronary Arterial Pressure and Flow in Normal and Damaged Hearts

Effects of Alloxan-Induced Diabetes on Ischemia-Reperfusion Injury in Rabbit Hearts

Influence of Glucose and Insulin on the Exaggerated Diastolic and Systolic Dysfunction of Hypertrophied Rat Hearts During Hypoxia

Comparison of acute alterations in left ventricular relaxation and diastolic chamber stiffness induced by hypoxia and ischemia. Role of myocardial oxygen supply-demand imbalance

Effects of Reperfusion after Coronary Artery Occlusion on Post-infarction Scar Tissue

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