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Demyelinating Diseases: From Molecular Mechanisms to Therapeutic Strategies

International journal of molecular sciences, 2023-02, Vol.24 (5), p.4596

2023

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Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ

Scientific reports, 2021-03, Vol.11 (1), p.4952-4952, Article 4952

2021

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Human iPSC-Derived Astrocytes: A Powerful Tool to Study Primary Astrocyte Dysfunction in the Pathogenesis of Rare Leukodystrophies

International journal of molecular sciences, 2021-12, Vol.23 (1), p.274

2021

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The Antihypertensive Drug Telmisartan Protects Oligodendrocytes from Cholesterol Accumulation and Promotes Differentiation by a PPAR-γ-Mediated Mechanism

International journal of molecular sciences, 2021-09, Vol.22 (17), p.9434

2021

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The mitochondrial uncoupling protein‐2 is a master regulator of both M1 and M2 microglial responses

Journal of neurochemistry, 2015-10, Vol.135 (1), p.147-156

2015

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Myelin Defects in Niemann–Pick Type C Disease: Mechanisms and Possible Therapeutic Perspectives

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8858

2021

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NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation

International journal of molecular sciences, 2020-09, Vol.21 (19), p.7216

2020

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Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study

International journal of molecular sciences, 2022-03, Vol.23 (7), p.3456

2022

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DRP1 Inhibition Rescues Mitochondrial Integrity and Excessive Apoptosis in CS-A Disease Cell Models

International journal of molecular sciences, 2021-07, Vol.22 (13), p.7123

2021

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The CaMKII/MLC1 Axis Confers Ca2+-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes

Cells (Basel, Switzerland), 2022-08, Vol.11 (17), p.2656

2022

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Megalencephalic Leukoencephalopathy with Subcortical Cysts Disease-Linked MLC1 Protein Favors Gap-Junction Intercellular Communication by Regulating Connexin 43 Trafficking in Astrocytes

Cells (Basel, Switzerland), 2020-06, Vol.9 (6), p.1425

2020

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A Calsequestrin-1 Mutation Associated with a Skeletal Muscle Disease Alters Sarcoplasmic Ca2+ Release

PloS one, 2016-05, Vol.11 (5), p.e0155516-e0155516

2016

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Megalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: Relevance to MLC disease pathogenesis

Neurobiology of disease, 2014-06, Vol.66 (100), p.1-18

2014

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hMTH1 expression protects mitochondria from Huntington's disease-like impairment

Neurobiology of disease, 2013-01, Vol.49 (12), p.148-158

2013

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Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals

Biochimica et biophysica acta, 2013-05, Vol.1832 (5), p.650-659

2013

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Two different ionotropic receptors are activated by ATP in rat microglia

The Journal of physiology, 1999-09, Vol.519 (3), p.723-736

1999

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Adenosine A2A receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes

Scientific reports, 2019-07, Vol.9 (1), p.1-10, Article 9782

2019

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The activity of the Striatal‐enriched protein tyrosine phosphatase in neuronal cells is modulated by adenosine A2A receptor

Journal of neurochemistry, 2020-02, Vol.152 (3), p.284-298

2020

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The activity of the Striatal-enriched protein tyrosine phosphatase in neuronal cells is modulated by adenosine A 2A receptor

Journal of neurochemistry, 2020-02, Vol.152 (3), p.284-298

2020

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The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients

The Journal of neuroscience, 2013-09, Vol.33 (39), p.15388-15393

2013

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TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression

Journal of neurochemistry, 2010-10, Vol.115 (2), p.450-459

2010

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Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves

Journal of neuropathology and experimental neurology, 2011-10, Vol.70 (10), p.900-912

2011

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Peroxisome Proliferator-Activated Receptor γ Agonists Accelerate Oligodendrocyte Maturation and Influence Mitochondrial Functions and Oscillatory Ca2+ Waves

Journal of neuropathology and experimental neurology, 2011-10, Vol.70 (10), p.900-912

2011

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NRF2 and PPAR-y Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation

International journal of molecular sciences, 2020-10, Vol.21 (19), p.1

2020

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Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes

Human molecular genetics, 2016-04, Vol.25 (8), p.1543-1558

2016

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Demyelinating Diseases: From Molecular Mechanisms to Therapeutic Strategies

Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ

Human iPSC-Derived Astrocytes: A Powerful Tool to Study Primary Astrocyte Dysfunction in the Pathogenesis of Rare Leukodystrophies

The Antihypertensive Drug Telmisartan Protects Oligodendrocytes from Cholesterol Accumulation and Promotes Differentiation by a PPAR-γ-Mediated Mechanism

The mitochondrial uncoupling protein‐2 is a master regulator of both M1 and M2 microglial responses

Myelin Defects in Niemann–Pick Type C Disease: Mechanisms and Possible Therapeutic Perspectives

NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation

Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study

DRP1 Inhibition Rescues Mitochondrial Integrity and Excessive Apoptosis in CS-A Disease Cell Models

The CaMKII/MLC1 Axis Confers Ca2+-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes

Megalencephalic Leukoencephalopathy with Subcortical Cysts Disease-Linked MLC1 Protein Favors Gap-Junction Intercellular Communication by Regulating Connexin 43 Trafficking in Astrocytes

A Calsequestrin-1 Mutation Associated with a Skeletal Muscle Disease Alters Sarcoplasmic Ca2+ Release

Megalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: Relevance to MLC disease pathogenesis

hMTH1 expression protects mitochondria from Huntington's disease-like impairment

Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals

Two different ionotropic receptors are activated by ATP in rat microglia

Adenosine A2A receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes

The activity of the Striatal‐enriched protein tyrosine phosphatase in neuronal cells is modulated by adenosine A2A receptor

The activity of the Striatal-enriched protein tyrosine phosphatase in neuronal cells is modulated by adenosine A 2A receptor

The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients

TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression

Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves

Peroxisome Proliferator-Activated Receptor γ Agonists Accelerate Oligodendrocyte Maturation and Influence Mitochondrial Functions and Oscillatory Ca2+ Waves

NRF2 and PPAR-y Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation

Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes

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