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Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (47), p.12046-12050

2018

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Pulmonary Vascular Volume by Quantitative CT in Dyspneic Smokers with Minor Emphysema

Chronic obstructive pulmonary disease, 2023-12, Vol.20 (1), p.135-143

2023

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Mechanosensitivity of Murine Lung Slowly Adapting Receptors: Minimal Impact of Chemosensory, Serotonergic, and Purinergic Signaling

Frontiers in physiology, 2022-02, Vol.13, p.833665-833665

2022

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Beyond Spirometry: Linking Wasted Ventilation to Exertional Dyspnea in the Initial Stages of COPD

Chronic obstructive pulmonary disease, 2024-12, Vol.21 (1), p.2301549-2301549

2024

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Loss of vagally mediated bradycardia and bronchoconstriction in mice lacking M2 or M3 muscarinic acetylcholine receptors

The FASEB journal, 2004-04, Vol.18 (6), p.711-713

2004

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Evaluation of Dynamic Respiratory Mechanical Abnormalities During Conventional CPET

Frontiers in medicine, 2020-09, Vol.7, p.548-548

2020

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In vivo cardiopulmonary impact of skeletal M3Dq DREADD expression: a pilot study

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2021-11, Vol.191 (6), p.1059-1070

2021

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Unraveling the Causes of Unexplained Dyspnea: The Value of Exercise Testing

Clinics in chest medicine, 2019-06, Vol.40 (2), p.471-499

2019

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Exertional dyspnoea in patients with mild‐to‐severe chronic obstructive pulmonary disease: neuromechanical mechanisms

The Journal of physiology, 2022-09, Vol.600 (18), p.4227-4245

2022

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Low resting diffusion capacity, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease

Journal of applied physiology (1985), 2019-10, Vol.127 (4), p.1107-1116

2019

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Qualitative Components of Dyspnea during Incremental Exercise across the COPD Continuum

Medicine and science in sports and exercise, 2021-12, Vol.53 (12), p.2467-2476

2021

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Physiological predictors of morbidity and mortality in COPD: the relative importance of reduced inspiratory capacity and inspiratory muscle strength

Journal of applied physiology (1985), 2022-09, Vol.133 (3), p.679-688

2022

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Dynamic Ventilatory Reserve During Incremental Exercise: Reference Values and Clinical Validation in Chronic Obstructive Pulmonary Disease

Annals of the American Thoracic Society, 2023-10, Vol.20 (10), p.1425-1434

2023

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Physiological underpinnings of exertional dyspnoea in mild fibrosing interstitial lung disease

Respiratory physiology & neurobiology, 2023-06, Vol.312, p.104041-104041, Article 104041

2023

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Neurophysiological mechanisms of exertional dyspnea in post-pulmonary embolism syndrome

Journal of applied physiology (1985), 2023-03, Vol.134 (3), p.667-677

2023

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Reduced exercise tolerance in mild chronic obstructive pulmonary disease: The contribution of combined abnormalities of diffusing capacity for carbon monoxide and ventilatory efficiency

Respirology (Carlton, Vic.), 2021-08, Vol.26 (8), p.786-795

2021

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Elevated exercise ventilation in mild COPD is not linked to enhanced central chemosensitivity

Respiratory physiology & neurobiology, 2021-02, Vol.284, p.103571-103571, Article 103571

2021

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Compensatory responses to increased mechanical abnormalities in COPD during sleep

European journal of applied physiology, 2022-03, Vol.122 (3), p.663-676

2022

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Mechanisms of Exertional Dyspnea in Patients with Mild COPD and a Low Resting DLCO

Chronic obstructive pulmonary disease, 2021-09, Vol.18 (5), p.501-510

2021

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Deterioration of Nighttime Respiratory Mechanics in COPD: Impact of Bronchodilator Therapy

Chest, 2021-01, Vol.159 (1), p.116-127

2021

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Mechanisms of Exertional Dyspnea in Patients with Mild COPD and a Low Resting DL CO

Chronic obstructive pulmonary disease, 2021-10, Vol.18 (5), p.501-510

2021

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Severe Exertional Dyspnea in an Ex-Smoker with a Large Apical Bulla

Annals of the American Thoracic Society, 2018-10, Vol.15 (10), p.1221-1228

2018

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murine model of hyperdopaminergic state displays altered respiratory control

The FASEB journal, 2007-05, Vol.21 (7), p.1463-1471

2007

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In vivo cardiopulmonary impact of skeletal M 3 Dq DREADD expression: a pilot study

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2021-11, Vol.191 (6), p.1059

2021

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Interaction of hypoxia and core temperature: potential role of TRPV1

Advances in experimental medicine and biology, 2012, Vol.758, p.173

2012

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Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists

Pulmonary Vascular Volume by Quantitative CT in Dyspneic Smokers with Minor Emphysema

Mechanosensitivity of Murine Lung Slowly Adapting Receptors: Minimal Impact of Chemosensory, Serotonergic, and Purinergic Signaling

Beyond Spirometry: Linking Wasted Ventilation to Exertional Dyspnea in the Initial Stages of COPD

Loss of vagally mediated bradycardia and bronchoconstriction in mice lacking M2 or M3 muscarinic acetylcholine receptors

Evaluation of Dynamic Respiratory Mechanical Abnormalities During Conventional CPET

In vivo cardiopulmonary impact of skeletal M3Dq DREADD expression: a pilot study

Unraveling the Causes of Unexplained Dyspnea: The Value of Exercise Testing

Exertional dyspnoea in patients with mild‐to‐severe chronic obstructive pulmonary disease: neuromechanical mechanisms

Low resting diffusion capacity, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease

Qualitative Components of Dyspnea during Incremental Exercise across the COPD Continuum

Physiological predictors of morbidity and mortality in COPD: the relative importance of reduced inspiratory capacity and inspiratory muscle strength

Dynamic Ventilatory Reserve During Incremental Exercise: Reference Values and Clinical Validation in Chronic Obstructive Pulmonary Disease

Physiological underpinnings of exertional dyspnoea in mild fibrosing interstitial lung disease

Neurophysiological mechanisms of exertional dyspnea in post-pulmonary embolism syndrome

Reduced exercise tolerance in mild chronic obstructive pulmonary disease: The contribution of combined abnormalities of diffusing capacity for carbon monoxide and ventilatory efficiency

Elevated exercise ventilation in mild COPD is not linked to enhanced central chemosensitivity

Compensatory responses to increased mechanical abnormalities in COPD during sleep

Mechanisms of Exertional Dyspnea in Patients with Mild COPD and a Low Resting DLCO

Deterioration of Nighttime Respiratory Mechanics in COPD: Impact of Bronchodilator Therapy

Mechanisms of Exertional Dyspnea in Patients with Mild COPD and a Low Resting DL CO

Severe Exertional Dyspnea in an Ex-Smoker with a Large Apical Bulla

murine model of hyperdopaminergic state displays altered respiratory control

In vivo cardiopulmonary impact of skeletal M 3 Dq DREADD expression: a pilot study

Interaction of hypoxia and core temperature: potential role of TRPV1

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