UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 258

Sortiert nach

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

Archives of toxicology, 2016-12, Vol.90 (12), p.2979-3003

2016

Link zum Volltext

Verfügbarkeit prüfen

Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates

Archives of toxicology, 2020-09, Vol.94 (9), p.3027-3032

2020

Link zum Volltext

Verfügbarkeit prüfen

A Comparative Linear Interaction Energy and MM/PBSA Study on SIRT1–Ligand Binding Free Energy Calculation

Journal of chemical information and modeling, 2019-09, Vol.59 (9), p.4018-4033

2019

Link zum Volltext

Verfügbarkeit prüfen

Linear Interaction Energy Based Prediction of Cytochrome P450 1A2 Binding Affinities with Reliability Estimation

PloS one, 2015-11, Vol.10 (11), p.e0142232

2015

Link zum Volltext

Verfügbarkeit prüfen

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae

PloS one, 2017-03, Vol.12 (3), p.e0173573-e0173573

2017

Link zum Volltext

Verfügbarkeit prüfen

Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity

Analytical and bioanalytical chemistry, 2016-02, Vol.408 (5), p.1425-1443

2016

Link zum Volltext

Verfügbarkeit prüfen

Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations

Chemical research in toxicology, 2018-02, Vol.31 (2), p.116-126

2018

Link zum Volltext

Verfügbarkeit prüfen

Human NAD(P)H:quinone Oxidoreductase 1 (NQO1)-Mediated Inactivation of Reactive Quinoneimine Metabolites of Diclofenac and Mefenamic Acid

Chemical research in toxicology, 2014-04, Vol.27 (4), p.576-586

2014

Link zum Volltext

Verfügbarkeit prüfen

Diclofenac inhibits tumor necrosis factor‐α‐induced nuclear factor‐κB activation causing synergistic hepatocyte apoptosis

Hepatology (Baltimore, Md.), 2011-06, Vol.53 (6), p.2027-2041

2011

Link zum Volltext

Verfügbarkeit prüfen

Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques

Drug metabolism and disposition, 2009-03, Vol.37 (3), p.658

2009

Link zum Volltext

Verfügbarkeit prüfen

Cytochrome P450-Mediated Bioactivation of Mefenamic Acid to Quinoneimine Intermediates and Inactivation by Human Glutathione S‑Transferases

Chemical research in toxicology, 2014-12, Vol.27 (12), p.2071-2081

2014

Link zum Volltext

Verfügbarkeit prüfen

Catalytic Site Prediction and Virtual Screening of Cytochrome P450 2D6 Substrates by Consideration of Water and Rescoring in Automated Docking

Journal of medicinal chemistry, 2006-04, Vol.49 (8), p.2417-2430

2006

Link zum Volltext

Verfügbarkeit prüfen

Virtual Screening and Prediction of Site of Metabolism for Cytochrome P450 1A2 Ligands

Journal of Chemical Information and Modeling, 2009-01, Vol.49 (1), p.43-52

2009

Link zum Volltext

Verfügbarkeit prüfen

Binding Mode Prediction of Cytochrome P450 and Thymidine Kinase Protein−Ligand Complexes by Consideration of Water and Rescoring in Automated Docking

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2308-2318

2005

Link zum Volltext

Verfügbarkeit prüfen

Effect of Human Glutathione S‑Transferases on Glutathione-Dependent Inactivation of Cytochrome P450-Dependent Reactive Intermediates of Diclofenac

Chemical research in toxicology, 2013-11, Vol.26 (11), p.1632-1641

2013

Link zum Volltext

Verfügbarkeit prüfen

Mass Spectrometric Characterization of Protein Adducts of Multiple P450-Dependent Reactive Intermediates of Diclofenac to Human Glutathione‑S‑transferase P1‑1

Chemical research in toxicology, 2012-11, Vol.25 (11), p.2532-2541

2012

Link zum Volltext

Verfügbarkeit prüfen

Characterization of Human Cytochrome P450s Involved in the Bioactivation of Tri-ortho-cresyl Phosphate (ToCP)

Chemical research in toxicology, 2015-04, Vol.28 (4), p.711-721

2015

Link zum Volltext

Verfügbarkeit prüfen

Enzyme-catalyzed activation of anticancer prodrugs

Pharmacological reviews, 2004-03, Vol.56 (1), p.53

2004

Link zum Volltext

Verfügbarkeit prüfen

Metabolism related toxicity of diclofenac in yeast as model system

Toxicology letters, 2011-02, Vol.200 (3), p.162-168

2011

Link zum Volltext

Verfügbarkeit prüfen

Involvement of the Pleiotropic Drug Resistance Response, Protein Kinase C Signaling, and Altered Zinc Homeostasis in Resistance of Saccharomyces cerevisiae to Diclofenac

Applied and Environmental Microbiology, 2011-09, Vol.77 (17), p.5973-5980

2011

Link zum Volltext

Verfügbarkeit prüfen

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

Applied microbiology and biotechnology, 2018-11, Vol.102 (21), p.9231-9242

2018

Link zum Volltext

Verfügbarkeit prüfen

Computational prediction of binding affinity for CYP1A2-ligand complexes using empirical free energy calculations

Drug metabolism and disposition, 2010-08, Vol.38 (8), p.1347

2010

Link zum Volltext

Verfügbarkeit prüfen

eTOX ALLIES: an automated pipeLine for linear interaction energy-based simulations

Journal of cheminformatics, 2017-11, Vol.9 (1), p.58-13, Article 58

2017

Link zum Volltext

Verfügbarkeit prüfen

Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-03, Vol.878 (7), p.667-674

2010

Link zum Volltext

Verfügbarkeit prüfen

Liquid chromatography/tandem mass spectrometry detection of covalent binding of acetaminophen to human serum albumin

Drug metabolism and disposition, 2007-08, Vol.35 (8), p.1408

2007

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 258

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(249)
Mit Volltextzugriff
(228)

Publikationsform

Artikel
(257)
Buchkapitel
(1)

Sprache

Englisch
(257)
Japanisch
(43)
Deutsch
(1)

Erscheinungsjahr

n.n

Thema

Science & Technology
(219)
Life Sciences & Biomedicine
(208)
Pharmacology & Pharmacy
(117)
Animals
(99)
Humans
(99)
Toxicology
(86)
Biological And Medical Sciences
(85)
Rats
(73)
Chemistry
(71)
Physical Sciences
(70)
Medical Sciences
(65)
Biochemistry & Molecular Biology
(60)
Cytochrome P-450 Enzyme System - Metabolism
(57)
Chemistry, Medicinal
(49)
Male
(46)
Pharmacology. Drug Treatments
(44)
Chemistry, Multidisciplinary
(39)
Models, Molecular
(32)
Cytochrome P450
(31)
Substrate Specificity
(30)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates

A Comparative Linear Interaction Energy and MM/PBSA Study on SIRT1–Ligand Binding Free Energy Calculation

Linear Interaction Energy Based Prediction of Cytochrome P450 1A2 Binding Affinities with Reliability Estimation

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae

Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity

Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations

Human NAD(P)H:quinone Oxidoreductase 1 (NQO1)-Mediated Inactivation of Reactive Quinoneimine Metabolites of Diclofenac and Mefenamic Acid

Diclofenac inhibits tumor necrosis factor‐α‐induced nuclear factor‐κB activation causing synergistic hepatocyte apoptosis

Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques

Cytochrome P450-Mediated Bioactivation of Mefenamic Acid to Quinoneimine Intermediates and Inactivation by Human Glutathione S‑Transferases

Catalytic Site Prediction and Virtual Screening of Cytochrome P450 2D6 Substrates by Consideration of Water and Rescoring in Automated Docking

Virtual Screening and Prediction of Site of Metabolism for Cytochrome P450 1A2 Ligands

Binding Mode Prediction of Cytochrome P450 and Thymidine Kinase Protein−Ligand Complexes by Consideration of Water and Rescoring in Automated Docking

Effect of Human Glutathione S‑Transferases on Glutathione-Dependent Inactivation of Cytochrome P450-Dependent Reactive Intermediates of Diclofenac

Mass Spectrometric Characterization of Protein Adducts of Multiple P450-Dependent Reactive Intermediates of Diclofenac to Human Glutathione‑S‑transferase P1‑1

Characterization of Human Cytochrome P450s Involved in the Bioactivation of Tri-ortho-cresyl Phosphate (ToCP)

Enzyme-catalyzed activation of anticancer prodrugs

Metabolism related toxicity of diclofenac in yeast as model system

Involvement of the Pleiotropic Drug Resistance Response, Protein Kinase C Signaling, and Altered Zinc Homeostasis in Resistance of Saccharomyces cerevisiae to Diclofenac

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

Computational prediction of binding affinity for CYP1A2-ligand complexes using empirical free energy calculations

eTOX ALLIES: an automated pipeLine for linear interaction energy-based simulations

Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR

Liquid chromatography/tandem mass spectrometry detection of covalent binding of acetaminophen to human serum albumin

Suchergebnisse filtern