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Human Sinoatrial Node Pacemaker Activity: Role of the Slow Component of the Delayed Rectifier K+ Current, IKs

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7264

2023

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Pacemaker activity of the human sinoatrial node: an update on the effects of mutations in HCN4 on the hyperpolarization-activated current

International journal of molecular sciences, 2015-01, Vol.16 (2), p.3071-3094

2015

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Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?

Stem cells and development, 2015-05, Vol.24 (9), p.1035-1052

2015

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Injection of IK1 through dynamic clamp can make all the difference in patch-clamp studies on hiPSC-derived cardiomyocytes

Frontiers in physiology, 2023-12, Vol.14, p.1326160-1326160

2023

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Effects of Acute Hypernatremia on the Electrophysiology of Single Human Ventricular Cardiomyocytes: An In Silico Study

Reviews in cardiovascular medicine, 2024-06, Vol.25 (6), p.194

2024

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Zebrafish as a Model System for Brugada Syndrome

Reviews in cardiovascular medicine, 2024-09, Vol.25 (9), p.313

2024

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Identification and functional characterization of cardiac pacemaker cells in zebrafish

PloS one, 2012-10, Vol.7 (10), p.e47644-e47644

2012

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The Antidepressant Paroxetine Reduces the Cardiac Sodium Current

International journal of molecular sciences, 2023-01, Vol.24 (3), p.1904

2023

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RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling

Circulation (New York, N.Y.), 2018-09, Vol.138 (13), p.1330-1342

2018

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Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells

Nature biotechnology, 2015-09, Vol.33 (9), p.970-979

2015

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Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology

EMBO molecular medicine, 2015-04, Vol.7 (4), p.394-410

2015

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Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (50), p.17707-17707

2014

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Functional Characterization of the A414G Loss-of-Function Mutation in HCN4 Associated with Sinus Bradycardia

Cardiogenetics, 2023-09, Vol.13 (3), p.117-134

2023

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Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program

Development (Cambridge), 2019-01, Vol.146 (8)

2019

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Aquaporin Channels in the Heart-Physiology and Pathophysiology

International journal of molecular sciences, 2019-04, Vol.20 (8), p.2039

2019

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Cardiomyocytes Derived From Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease

Circulation (New York, N.Y.), 2012-06, Vol.125 (25), p.3079-3091

2012

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The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes

International journal of molecular sciences, 2023-10, Vol.24 (20), p.15290

2023

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HCN4 current during human sinoatrial node-like action potentials

Progress in biophysics and molecular biology, 2021-11, Vol.166, p.105-118

2021

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The Action Potential Clamp Technique as a Tool for Risk Stratification of Sinus Bradycardia Due to Loss-of-Function Mutations in HCN4: An In Silico Exploration Based on In Vitro and In Vivo Data

Biomedicines, 2023-09, Vol.11 (9), p.2447

2023

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Pacemaker activity of the human sinoatrial node: effects of HCN4 mutations on the hyperpolarization-activated current

Europace (London, England), 2014-03, Vol.16 (3), p.384-395

2014

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HCN4 Mutations in Multiple Families With Bradycardia and Left Ventricular Noncompaction Cardiomyopathy

Journal of the American College of Cardiology, 2014-08, Vol.64 (8), p.745-756

2014

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Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp

International journal of molecular sciences, 2017-08, Vol.18 (9), p.1873

2017

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Zebrafish: a novel research tool for cardiac (patho)electrophysiology and ion channel disorders

Frontiers in physiology, 2012-01, Vol.3, p.255-255

2012

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Long QT Syndrome and Sinus Bradycardia-A Mini Review

Frontiers in cardiovascular medicine, 2018-08, Vol.5, p.106-106

2018

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Embryonic Tbx3 + cardiomyocytes form the mature cardiac conduction system by progressive fate restriction

Development (Cambridge), 2018-09, Vol.145 (17)

2018

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Human Sinoatrial Node Pacemaker Activity: Role of the Slow Component of the Delayed Rectifier K+ Current, IKs

Pacemaker activity of the human sinoatrial node: an update on the effects of mutations in HCN4 on the hyperpolarization-activated current

Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?

Injection of IK1 through dynamic clamp can make all the difference in patch-clamp studies on hiPSC-derived cardiomyocytes

Effects of Acute Hypernatremia on the Electrophysiology of Single Human Ventricular Cardiomyocytes: An In Silico Study

Zebrafish as a Model System for Brugada Syndrome

Identification and functional characterization of cardiac pacemaker cells in zebrafish

The Antidepressant Paroxetine Reduces the Cardiac Sodium Current

RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling

Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells

Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology

Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue

Functional Characterization of the A414G Loss-of-Function Mutation in HCN4 Associated with Sinus Bradycardia

Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program

Aquaporin Channels in the Heart-Physiology and Pathophysiology

Cardiomyocytes Derived From Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease

The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes

HCN4 current during human sinoatrial node-like action potentials

The Action Potential Clamp Technique as a Tool for Risk Stratification of Sinus Bradycardia Due to Loss-of-Function Mutations in HCN4: An In Silico Exploration Based on In Vitro and In Vivo Data

Pacemaker activity of the human sinoatrial node: effects of HCN4 mutations on the hyperpolarization-activated current

HCN4 Mutations in Multiple Families With Bradycardia and Left Ventricular Noncompaction Cardiomyopathy

Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp

Zebrafish: a novel research tool for cardiac (patho)electrophysiology and ion channel disorders

Long QT Syndrome and Sinus Bradycardia-A Mini Review

Embryonic Tbx3 + cardiomyocytes form the mature cardiac conduction system by progressive fate restriction

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