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GPCR activation mechanisms across classes and macro/microscales

Nature structural & molecular biology, 2021-11, Vol.28 (11), p.879-888

2021

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Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

Nature (London), 2016-08, Vol.536 (7617), p.484-487

2016

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Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action

Cell, 2014-02, Vol.156 (5), p.963-974

2014

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A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

Nature communications, 2017-04, Vol.8 (1), p.15054-15054, Article 15054

2017

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Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

Nature communications, 2019-03, Vol.10 (1), p.1261-1261, Article 1261

2019

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Large-scale production and protein engineering of G protein-coupled receptors for structural studies

Frontiers in pharmacology, 2015-03, Vol.6, p.66-66

2015

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Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F

Nature structural & molecular biology, 2014-12, Vol.21 (12), p.1097-1099

2014

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Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (30), p.10360-10365

2008

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High-throughput mutagenesis using a two-fragment PCR approach

Scientific reports, 2017-07, Vol.7 (1), p.6787-11, Article 6787

2017

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Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f

Nature communications, 2024-08, Vol.15 (1), p.7555-12, Article 7555

2024

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GPCR Activation States Induced by Nanobodies and Mini-G Proteins Compared by NMR Spectroscopy

Molecules (Basel, Switzerland), 2020-12, Vol.25 (24), p.5984

2020

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Stabilization of G protein-coupled receptors by point mutations

Frontiers in pharmacology, 2015-04, Vol.6, p.82-82

2015

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Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers

The EMBO journal, 2011-03, Vol.30 (5), p.959-971

2011

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Modulation of the Oligomerization State of p53 by Differential Binding of Proteins of the S100 Family to p53 Monomers and Tetramers

The Journal of biological chemistry, 2009-05, Vol.284 (20), p.13804-13811

2009

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Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein

PloS one, 2014-06, Vol.9 (6), p.e98714-e98714

2014

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Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors

Frontiers in pharmacology, 2023-08, Vol.14, p.1158091-1158091

2023

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Production and purification of human Hsp90β in Escherichia coli

PloS one, 2017-06, Vol.12 (6), p.e0180047-e0180047

2017

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Cooperative Binding of Tetrameric p53 to DNA

Journal of molecular biology, 2004-08, Vol.341 (5), p.1145-1159

2004

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Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (20), p.8251-8256

2011

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Structural Evolution of p53, p63, and p73: Implication for Heterotetramer Formation

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (42), p.17705-17710

2009

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ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes

Cell, 2006-04, Vol.125 (1), p.99-111

2006

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Proteins of the S100 Family Regulate the Oligomerization of p53 Tumor Suppressor

Proceedings of the National Academy of Sciences - PNAS, 2005-03, Vol.102 (13), p.4735-4740

2005

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Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.16906-16910

2012

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Stability of p53 homologs

PloS one, 2012-10, Vol.7 (10), p.e47889-e47889

2012

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Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

BMC genomics, 2009-12, Vol.10 (1), p.628-628, Article 628

2009

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GPCR activation mechanisms across classes and macro/microscales

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

Large-scale production and protein engineering of G protein-coupled receptors for structural studies

Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

High-throughput mutagenesis using a two-fragment PCR approach

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f

GPCR Activation States Induced by Nanobodies and Mini-G Proteins Compared by NMR Spectroscopy

Stabilization of G protein-coupled receptors by point mutations

Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers

Modulation of the Oligomerization State of p53 by Differential Binding of Proteins of the S100 Family to p53 Monomers and Tetramers

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein

Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors

Production and purification of human Hsp90β in Escherichia coli

Cooperative Binding of Tetrameric p53 to DNA

Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

Structural Evolution of p53, p63, and p73: Implication for Heterotetramer Formation

ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes

Proteins of the S100 Family Regulate the Oligomerization of p53 Tumor Suppressor

Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2

Stability of p53 homologs

Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

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