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G Protein-Coupled Receptors: Dynamic Machines for Signaling Pain and Itch

Neuron (Cambridge, Mass.), 2015-11, Vol.88 (4), p.635-649

2015

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The G protein-coupled receptor-transient receptor potential channel axis: molecular insights for targeting disorders of sensation and inflammation

Pharmacological reviews, 2015-01, Vol.67 (1), p.36-73

2015

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Mini-review: Dissecting receptor-mediated stimulation of TRPV4 in nociceptive and inflammatory pathways

Neuroscience letters, 2022-01, Vol.770, p.136377-136377, Article 136377

2022

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Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (46), p.12309-12314

2017

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Cellular Interactions of Liposomes and PISA Nanoparticles during Human Blood Flow in a Microvascular Network

Small (Weinheim an der Bergstrasse, Germany), 2020-08, Vol.16 (33), p.e2002861-n/a

2020

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Diverse Roles of TRPV4 in Macrophages: A Need for Unbiased Profiling

Frontiers in immunology, 2022-01, Vol.12, p.828115-828115

2022

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Selective G protein signaling driven by substance P-neurokinin receptor dynamics

Nature chemical biology, 2022-01, Vol.18 (1), p.109-115

2022

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Protease-activated Receptor 2 (PAR2) Protein and Transient Receptor Potential Vanilloid 4 (TRPV4) Protein Coupling Is Required for Sustained Inflammatory Signaling

The Journal of biological chemistry, 2013-02, Vol.288 (8), p.5790-5802

2013

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Cathepsin S Causes Inflammatory Pain via Biased Agonism of PAR2 and TRPV4

The Journal of biological chemistry, 2014-09, Vol.289 (39), p.27215-27234

2014

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P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells

The Journal of biological chemistry, 2015-11, Vol.290 (48), p.29051-29062

2015

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Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

Nature communications, 2022-02, Vol.13 (1), p.646-646, Article 646

2022

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A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain

Nature nanotechnology, 2019-12, Vol.14 (12), p.1150-1159

2019

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Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (26), p.15281-15292

2020

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G-Protein–Coupled Receptors Are Dynamic Regulators of Digestion and Targets for Digestive Diseases

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.1600-1616

2019

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A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY

Scientific reports, 2018-01, Vol.8 (1), p.667-15, Article 667

2018

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Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome

Gastroenterology (New York, N.Y. 1943), 2015-08, Vol.149 (2), p.433-444.e7

2015

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Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (22), p.e2220979120-e2220979120

2023

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Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (6), p.1

2022

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Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain

Biomaterials, 2022-06, Vol.285, p.121536-121536, Article 121536

2022

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Targeting endosomal receptors, a new direction for polymers in nanomedicine

Journal of materials chemistry. B, Materials for biology and medicine, 2023-06, Vol.11 (24), p.539-5399

2023

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Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain

Frontiers in molecular neuroscience, 2019-11, Vol.12, p.273-273

2019

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Inflammation-associated changes in DOR expression and function in the mouse colon

American journal of physiology: Gastrointestinal and liver physiology, 2018-10, Vol.315 (4), p.G544-G559

2018

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Editorial: New Insights into Mechanotransduction by Immune Cells in Physiological and Pathological Conditions

Frontiers in immunology, 2022-05, Vol.13, p.930362-930362

2022

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G Protein-Coupled Receptors: Dynamic Machines for Signaling Pain and Itch

The G protein-coupled receptor-transient receptor potential channel axis: molecular insights for targeting disorders of sensation and inflammation

Mini-review: Dissecting receptor-mediated stimulation of TRPV4 in nociceptive and inflammatory pathways

Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

Cellular Interactions of Liposomes and PISA Nanoparticles during Human Blood Flow in a Microvascular Network

Diverse Roles of TRPV4 in Macrophages: A Need for Unbiased Profiling

Selective G protein signaling driven by substance P-neurokinin receptor dynamics

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

Protease-activated Receptor 2 (PAR2) Protein and Transient Receptor Potential Vanilloid 4 (TRPV4) Protein Coupling Is Required for Sustained Inflammatory Signaling

Cathepsin S Causes Inflammatory Pain via Biased Agonism of PAR2 and TRPV4

P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain

Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain

G-Protein–Coupled Receptors Are Dynamic Regulators of Digestion and Targets for Digestive Diseases

A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY

Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome

Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief

Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain

Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain

Targeting endosomal receptors, a new direction for polymers in nanomedicine

Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain

Inflammation-associated changes in DOR expression and function in the mouse colon

Editorial: New Insights into Mechanotransduction by Immune Cells in Physiological and Pathological Conditions

Gut Analysis Toolbox: Automating quantitative analysis of enteric neurons

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