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Sex-related responses after traumatic brain injury: Considerations for preclinical modeling

Frontiers in neuroendocrinology, 2018-07, Vol.50, p.52-66

2018

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Targeting innate immunity for neurodegenerative disorders of the central nervous system

Journal of neurochemistry, 2016-09, Vol.138 (5), p.653-693

2016

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University of Kentucky Sanders-Brown healthy brain aging volunteers: donor characteristics, procedures and neuropathology

Current Alzheimer research, 2012-07, Vol.9 (6), p.724

2012

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Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease

The Journal of neuroscience, 2012-11, Vol.32 (46), p.16129-16140

2012

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Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

Journal of neuroinflammation, 2008-06, Vol.5 (1), p.28-28, Article 28

2008

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The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

Journal of neuropathology and experimental neurology, 2018-01, Vol.77 (1), p.2-20

2018

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Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice

Journal of neuroinflammation, 2020-04, Vol.17 (1), p.115-115, Article 115

2020

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Early chronic suppression of microglial p38α in a model of Alzheimer's disease does not significantly alter amyloid-associated neuropathology

PloS one, 2023-05, Vol.18 (5), p.e0286495-e0286495

2023

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Deletion of p38α MAPK in microglia blunts trauma-induced inflammatory responses in mice

Journal of neuroinflammation, 2019-05, Vol.16 (1), p.98-9, Article 98

2019

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Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFκB and MAPK dependent pathways in rat astrocytes

Brain research, 2009-09, Vol.1287, p.47-57

2009

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Closed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment

The Journal of neuroscience, 2015-04, Vol.35 (16), p.6554-6569

2015

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Brain arteriolosclerosis

Acta neuropathologica, 2021-01, Vol.141 (1), p.1-24

2021

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Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology

PloS one, 2022-01, Vol.17 (1), p.e0262474-e0262474

2022

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Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer's disease

Journal of neuroinflammation, 2020-09, Vol.17 (1), p.274-274, Article 274

2020

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Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

Acta neuropathologica, 2013-08, Vol.126 (2), p.161-177

2013

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Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

Alzheimer's research & therapy, 2013-05, Vol.5 (3), p.28-28

2013

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Hippocampal sclerosis in advanced age: clinical and pathological features

Brain (London, England : 1878), 2011-05, Vol.134 (Pt 5), p.1506-1518

2011

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Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)

Journal of neuroinflammation, 2011-07, Vol.8 (1), p.79-79, Article 79

2011

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The Effectiveness of Small-group Community-based Information Sessions on Clinical Trial Recruitment for Secondary Prevention of Alzheimer’s Disease

Alzheimer disease and associated disorders, 2017-04, Vol.31 (2), p.141-145

2017

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Blood Flow Deficits and Cerebrovascular Changes in a Dietary Model of Hyperhomocysteinemia

ASN neuro, 2019-07, Vol.11, p.1759091419865788-1759091419865788

2019

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MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult

Journal of neuroinflammation, 2008-08, Vol.5 (1), p.35-35, Article 35

2008

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Diffuse brain injury induces acute post-traumatic sleep

PloS one, 2014-01, Vol.9 (1), p.e82507-e82507

2014

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Plasma TDP‐43 levels are associated with neuroimaging measures of brain structure in limbic regions

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2023-04, Vol.15 (2), p.e12437-n/a

2023

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Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy

Nature communications, 2023-11, Vol.14 (1), p.6801-6801, Article 6801

2023

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The roles of inflammation and immune mechanisms in Alzheimer's disease

Alzheimer's & dementia : translational research & clinical interventions, 2016-06, Vol.2 (2), p.99-109

2016

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Sex-related responses after traumatic brain injury: Considerations for preclinical modeling

Targeting innate immunity for neurodegenerative disorders of the central nervous system

University of Kentucky Sanders-Brown healthy brain aging volunteers: donor characteristics, procedures and neuropathology

Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease

Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice

Early chronic suppression of microglial p38α in a model of Alzheimer's disease does not significantly alter amyloid-associated neuropathology

Deletion of p38α MAPK in microglia blunts trauma-induced inflammatory responses in mice

Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFκB and MAPK dependent pathways in rat astrocytes

Closed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment

Brain arteriolosclerosis

Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology

Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer's disease

Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

Hippocampal sclerosis in advanced age: clinical and pathological features

Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ)

The Effectiveness of Small-group Community-based Information Sessions on Clinical Trial Recruitment for Secondary Prevention of Alzheimer’s Disease

Blood Flow Deficits and Cerebrovascular Changes in a Dietary Model of Hyperhomocysteinemia

MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult

Diffuse brain injury induces acute post-traumatic sleep

Plasma TDP‐43 levels are associated with neuroimaging measures of brain structure in limbic regions

Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy

The roles of inflammation and immune mechanisms in Alzheimer's disease

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