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3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments

Advanced materials (Weinheim), 2019-03, Vol.31 (10), p.e1806899-n/a

2019

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CD133, Selectively Targeting the Root of Cancer

Toxins, 2016-05, Vol.8 (6), p.165

2016

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Natural killer cells unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapy

Seminars in immunology, 2017-06, Vol.31, p.64-75

2017

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IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function

Clinical cancer research, 2016-07, Vol.22 (14), p.3440-3450

2016

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A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells

Leukemia, 2021-06, Vol.35 (6), p.1586-1596

2021

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Eradication of Heterogeneous Tumors by T Cells Targeted with Combination Bispecific Chemically Self-assembled Nanorings

Molecular cancer therapeutics, 2023-03, Vol.22 (3), p.371-380

2023

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Generation of BiKEs and TriKEs to Improve NK Cell-Mediated Targeting of Tumor Cells

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1441, p.333

2016

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CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets

Blood, 2014-05, Vol.123 (19), p.3016-3026

2014

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Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies

Toxins, 2018-01, Vol.10 (1), p.32

2018

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Enhanced ADCC and NK Cell Activation of an Anticarcinoma Bispecific Antibody by Genetic Insertion of a Modified IL-15 Cross-linker

Molecular therapy, 2016-08, Vol.24 (7), p.1312-1322

2016

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Anti-NKG2C/IL-15/anti-CD33 killer engager directs primary and iPSC-derived NKG2C+ NK cells to target myeloid leukemia

Molecular therapy, 2021-12, Vol.29 (12), p.3410-3421

2021

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Targeting Natural Killer Cells to Acute Myeloid Leukemia In Vitro with a CD16×33 Bispecific Killer Cell Engager and ADAM17 Inhibition

Clinical cancer research, 2013-07, Vol.19 (14), p.3844-3855

2013

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Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition

Clinical cancer research, 2013-07, Vol.19 (14), p.3844-3855

2013

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Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production

Molecular cancer therapeutics, 2012-12, Vol.11 (12), p.2674-2684

2012

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A HER2 Tri-Specific NK Cell Engager Mediates Efficient Targeting of Human Ovarian Cancer

Cancers, 2021-08, Vol.13 (16), p.3994

2021

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Evaluation of 18-F-fluoro-2-deoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) as a staging and monitoring tool for dogs with stage-2 splenic hemangiosarcoma - A pilot study

PloS one, 2017-02, Vol.12 (2), p.e0172651-e0172651

2017

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161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

Blood advances, 2018-06, Vol.2 (12), p.1459-1469

2018

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NK-Cell-Mediated Targeting of Various Solid Tumors Using a B7-H3 Tri-Specific Killer Engager In Vitro and In Vivo

Cancers, 2020-09, Vol.12 (9), p.2659

2020

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Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker

Oncotarget, 2016-11, Vol.7 (45), p.73830-73844

2016

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Phase I study of a bispecific ligand-directed toxin targeting CD22 and CD19 (DT2219) for refractory B-cell malignancies

Clinical cancer research, 2015-03, Vol.21 (6), p.1267-1272

2015

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Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia

Blood, 2010-10, Vol.116 (14), p.2484-2493

2010

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Bispecific Targeting of EGFR and Urokinase Receptor (uPAR) Using Ligand-Targeted Toxins in Solid Tumors

Biomolecules (Basel, Switzerland), 2020-06, Vol.10 (6), p.956

2020

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Bispecific targeting of EGFR and uPAR in a mouse model of head and neck squamous cell carcinoma

Oral oncology, 2012-12, Vol.48 (12), p.1202-1207

2012

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Prosthetic Antigen Receptors

Journal of the American Chemical Society, 2015-08, Vol.137 (32), p.10108-10111

2015

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Immunotoxins Targeting B cell Malignancy-Progress and Problems With Immunogenicity

Biomedicines, 2018-12, Vol.7 (1), p.1

2018

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3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments

CD133, Selectively Targeting the Root of Cancer

Natural killer cells unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapy

IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function

A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells

Eradication of Heterogeneous Tumors by T Cells Targeted with Combination Bispecific Chemically Self-assembled Nanorings

Generation of BiKEs and TriKEs to Improve NK Cell-Mediated Targeting of Tumor Cells

CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets

Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies

Enhanced ADCC and NK Cell Activation of an Anticarcinoma Bispecific Antibody by Genetic Insertion of a Modified IL-15 Cross-linker

Anti-NKG2C/IL-15/anti-CD33 killer engager directs primary and iPSC-derived NKG2C+ NK cells to target myeloid leukemia

Targeting Natural Killer Cells to Acute Myeloid Leukemia In Vitro with a CD16×33 Bispecific Killer Cell Engager and ADAM17 Inhibition

Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition

Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production

A HER2 Tri-Specific NK Cell Engager Mediates Efficient Targeting of Human Ovarian Cancer

Evaluation of 18-F-fluoro-2-deoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) as a staging and monitoring tool for dogs with stage-2 splenic hemangiosarcoma - A pilot study

161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

NK-Cell-Mediated Targeting of Various Solid Tumors Using a B7-H3 Tri-Specific Killer Engager In Vitro and In Vivo

Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker

Phase I study of a bispecific ligand-directed toxin targeting CD22 and CD19 (DT2219) for refractory B-cell malignancies

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia

Bispecific Targeting of EGFR and Urokinase Receptor (uPAR) Using Ligand-Targeted Toxins in Solid Tumors

Bispecific targeting of EGFR and uPAR in a mouse model of head and neck squamous cell carcinoma

Prosthetic Antigen Receptors

Immunotoxins Targeting B cell Malignancy-Progress and Problems With Immunogenicity

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