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Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents

Cellular and molecular life sciences : CMLS, 2018-05, Vol.75 (9), p.1541-1558

2018

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Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway

International journal of molecular sciences, 2021-11, Vol.22 (21), p.12007

2021

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The endoplasmic reticulum (ER): a crucial cellular hub in flavivirus infection and potential target site for antiviral interventions

npj Viruses, 2024-06, Vol.2 (1), Article 24

2024

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Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide

International journal of molecular sciences, 2022-01, Vol.23 (2), p.584

2022

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Intracellular flow cytometry complements RT-qPCR detection of circulating SARS-CoV-2 variants of concern

BioTechniques, 2022-06, Vol.72 (6), p.245-254

2022

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Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interface

International journal of molecular sciences, 2023-05, Vol.24 (10), p.8765

2023

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Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors

Journal of Virology, 2008-11, Vol.82 (21), p.10366-10374

2008

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Small Molecule Cyclotriazadisulfonamide Abrogates the Upregulation of the Human Receptors CD4 and 4-1BB and Suppresses In Vitro Activation and Proliferation of T Lymphocytes

Frontiers in immunology, 2021-04, Vol.12, p.650731-650731

2021

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Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern

Frontiers in cellular and infection microbiology, 2022-08, Vol.12, p.989534-989534

2022

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Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation

PLoS biology, 2014-12, Vol.12 (12), p.e1002011

2014

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Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway

PloS one, 2018-12, Vol.13 (12), p.e0208641-e0208641

2018

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A Multimodal Imaging-Supported Down Syndrome Mouse Model of RSV Infection

Viruses, 2023-04, Vol.15 (4), p.993

2023

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Ribonuclease-neutralized pancreatic microsomal membranes from livestock for in vitro co-translational protein translocation

Analytical biochemistry, 2015-09, Vol.484, p.102-104

2015

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Accounting for population structure reveals ambiguity in the Zaire Ebolavirus reservoir dynamics

PLoS neglected tropical diseases, 2020-03, Vol.14 (3), p.e0008117-e0008117

2020

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Synthesis and evaluation of 3-alkynyl-5-aryl-7-aza-indoles as broad-spectrum antiviral agents

Frontiers in chemistry, 2022-10, Vol.10, p.1058229-1058229

2022

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Carbohydrate-Binding Agents Efficiently Prevent Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Nonintegrin (DC-SIGN)-Directed HIV-1 Transmission to T Lymphocytes

Molecular pharmacology, 2007-01, Vol.71 (1), p.3-11

2007

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Mannose-Specific Plant Lectins from the Amaryllidaceae Family Qualify as Efficient Microbicides for Prevention of Human Immunodeficiency Virus Infection

Antimicrobial Agents and Chemotherapy, 2004-10, Vol.48 (10), p.3858-3870

2004

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Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist

Journal of Virology, 2004-12, Vol.78 (23), p.12996-13006

2004

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Profile of Resistance of Human Immunodeficiency Virus to Mannose-Specific Plant Lectins

Journal of Virology, 2004-10, Vol.78 (19), p.10617-10627

2004

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Sugar-Binding Proteins Potently Inhibit Dendritic Cell Human Immunodeficiency Virus Type 1 (HIV-1) Infection and Dendritic-Cell-Directed HIV-1 Transfer

Journal of Virology, 2005-11, Vol.79 (21), p.13519-13527

2005

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Endothelial dysfunction in dengue virus pathology

Reviews in medical virology, 2015-01, Vol.25 (1), p.50-67

2015

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Advancing Marburg virus antiviral screening: Optimization of a novel T7 polymerase-independent minigenome system

Antiviral research, 2021-01, Vol.185, p.104977-104977, Article 104977

2021

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Specific CD4 down-modulating compounds with potent anti-HIV activity

Journal of leukocyte biology, 2003-11, Vol.74 (5), p.667-675

2003

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Human Immunodeficiency Virus Type 1 Escape from Cyclotriazadisulfonamide-Induced CD4-Targeted Entry Inhibition Is Associated with Increased Neutralizing Antibody Susceptibility

Journal of Virology, 2009-09, Vol.83 (18), p.9577-9583

2009

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SARS-CoV-2 Permissive glioblastoma cell line for high throughput antiviral screening

Antiviral research, 2022-07, Vol.203, p.105342-105342, Article 105342

2022

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Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents

Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway

The endoplasmic reticulum (ER): a crucial cellular hub in flavivirus infection and potential target site for antiviral interventions

Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide

Intracellular flow cytometry complements RT-qPCR detection of circulating SARS-CoV-2 variants of concern

Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interface

Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors

Small Molecule Cyclotriazadisulfonamide Abrogates the Upregulation of the Human Receptors CD4 and 4-1BB and Suppresses In Vitro Activation and Proliferation of T Lymphocytes

Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern

Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway

A Multimodal Imaging-Supported Down Syndrome Mouse Model of RSV Infection

Ribonuclease-neutralized pancreatic microsomal membranes from livestock for in vitro co-translational protein translocation

Accounting for population structure reveals ambiguity in the Zaire Ebolavirus reservoir dynamics

Synthesis and evaluation of 3-alkynyl-5-aryl-7-aza-indoles as broad-spectrum antiviral agents

Carbohydrate-Binding Agents Efficiently Prevent Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Nonintegrin (DC-SIGN)-Directed HIV-1 Transmission to T Lymphocytes

Mannose-Specific Plant Lectins from the Amaryllidaceae Family Qualify as Efficient Microbicides for Prevention of Human Immunodeficiency Virus Infection

Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist

Profile of Resistance of Human Immunodeficiency Virus to Mannose-Specific Plant Lectins

Sugar-Binding Proteins Potently Inhibit Dendritic Cell Human Immunodeficiency Virus Type 1 (HIV-1) Infection and Dendritic-Cell-Directed HIV-1 Transfer

Endothelial dysfunction in dengue virus pathology

Advancing Marburg virus antiviral screening: Optimization of a novel T7 polymerase-independent minigenome system

Specific CD4 down-modulating compounds with potent anti-HIV activity

Human Immunodeficiency Virus Type 1 Escape from Cyclotriazadisulfonamide-Induced CD4-Targeted Entry Inhibition Is Associated with Increased Neutralizing Antibody Susceptibility

SARS-CoV-2 Permissive glioblastoma cell line for high throughput antiviral screening

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