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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

Nature medicine, 2017-06, Vol.23 (6), p.703-713

2017

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KRAS and BRAF: drug targets and predictive biomarkers

The Journal of pathology, 2011-01, Vol.223 (2), p.220-230

2011

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Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer

Cancer cell, 2018-01, Vol.33 (1), p.125-136.e3

2018

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Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition

Cancer research (Chicago, Ill.), 2017-12, Vol.77 (23), p.6513-6523

2017

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Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

Nature (London), 2012-06, Vol.486 (7404), p.532-536

2012

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Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression

Cancer research (Chicago, Ill.), 2017-11, Vol.77 (22), p.6400-6414

2017

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Genetic Determinants of Outcome in Intrahepatic Cholangiocarcinoma

Hepatology (Baltimore, Md.), 2021-09, Vol.74 (3), p.1429-1444

2021

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Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights

Nature communications, 2021-11, Vol.12 (1), p.6821-6821, Article 6821

2021

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Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients

Clinical cancer research, 2015-03, Vol.21 (6), p.1313-1320

2015

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Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS

Nature communications, 2021-06, Vol.12 (1), p.3770-3770, Article 3770

2021

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Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

Genome biology, 2014-08, Vol.15 (8), p.454-454, Article 454

2014

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Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma

Modern pathology, 2016-11, Vol.29 (11), p.1433-1442

2016

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Comparative Genomic Analysis of Primary Versus Metastatic Colorectal Carcinomas

Journal of clinical oncology, 2012-08, Vol.30 (24), p.2956-2962

2012

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Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors

The American journal of surgical pathology, 2012-02, Vol.36 (2), p.173-184

2012

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Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

Nature genetics, 2013-03, Vol.45 (3), p.253-261

2013

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KRAS mutation influences recurrence patterns in patients undergoing hepatic resection of colorectal metastases

Cancer, 2014-12, Vol.120 (24), p.3965-3971

2014

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GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (19), p.E2008-E2017

2014

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Kras mutation is a marker of worse oncologic outcomes after percutaneous radiofrequency ablation of colorectal liver metastases

Oncotarget, 2017-09, Vol.8 (39), p.66117-66127

2017

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Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology–molecular associations: clinical and biological implications

Modern pathology, 2017-04, Vol.30 (4), p.599-609

2017

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Intrahepatic Cholangiocarcinomas Have Histologically and Immunophenotypically Distinct Small and Large Duct Patterns

The American journal of surgical pathology, 2018-10, Vol.42 (10), p.1334-1345

2018

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Cdc42 Mediates Cancer Cell Chemotaxis in Perineural Invasion

Molecular cancer research, 2020-06, Vol.18 (6), p.913-925

2020

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Logarithmic expansion of LGR5+ cells in human colorectal cancer

Cellular signalling, 2018-01, Vol.42, p.97-105

2018

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Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer

Cancer research (Chicago, Ill.), 2010-07, Vol.70 (14), p.5901-5911

2010

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Clinical and genetic determinants of ovarian metastases from colorectal cancer

Cancer, 2017-04, Vol.123 (7), p.1134-1143

2017

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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

KRAS and BRAF: drug targets and predictive biomarkers

Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer

Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression

Genetic Determinants of Outcome in Intrahepatic Cholangiocarcinoma

Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights

Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients

Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer

Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma

Comparative Genomic Analysis of Primary Versus Metastatic Colorectal Carcinomas

Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

KRAS mutation influences recurrence patterns in patients undergoing hepatic resection of colorectal metastases

GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling

Kras mutation is a marker of worse oncologic outcomes after percutaneous radiofrequency ablation of colorectal liver metastases

Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology–molecular associations: clinical and biological implications

Intrahepatic Cholangiocarcinomas Have Histologically and Immunophenotypically Distinct Small and Large Duct Patterns

Cdc42 Mediates Cancer Cell Chemotaxis in Perineural Invasion

Logarithmic expansion of LGR5+ cells in human colorectal cancer

Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer

Clinical and genetic determinants of ovarian metastases from colorectal cancer

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