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DOCK family proteins: key players in immune surveillance mechanisms

International immunology, 2020-01, Vol.32 (1), p.5-15

2020

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DOCK8 controls survival of group 3 innate lymphoid cells in the gut through Cdc42 activation

International immunology, 2021-03, Vol.33 (3), p.149-160

2021

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Selective role of neurokinin B in IL-31–induced itch response in mice

Journal of allergy and clinical immunology, 2019-10, Vol.144 (4), p.1130-1133.e8

2019

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Thymic epithelial cell–specific deletion of Jmjd6 reduces Aire protein expression and exacerbates disease development in a mouse model of autoimmune diabetes

Biochemical and biophysical research communications, 2017-07, Vol.489 (1), p.8-13

2017

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The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction

Nature communications, 2017-01, Vol.8 (1), p.13946-13946, Article 13946

2017

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DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

Blood, 2012-05, Vol.119 (19), p.4451-4461

2012

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Cancer-derived cholesterol sulfate is a key mediator to prevent tumor infiltration by effector T cells

International immunology, 2022-04, Vol.34 (5), p.277-289

2022

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DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction

The Journal of biological chemistry, 2017-02, Vol.292 (6), p.2191-2202

2017

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Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

Science signaling, 2018-07, Vol.11 (541)

2018

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S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer’s Patches

Cell reports (Cambridge), 2019-11, Vol.29 (9), p.2823-2834.e7

2019

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DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

The Journal of immunology (1950), 2014-12, Vol.193 (11), p.5660-5667

2014

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Cholesterol sulfate limits neutrophil recruitment and gut inflammation during mucosal injury

Frontiers in immunology, 2023-03, Vol.14, p.1131146-1131146

2023

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Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1

Cell reports (Cambridge), 2017-05, Vol.19 (5), p.969-980

2017

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The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production

Frontiers in immunology, 2018-02, Vol.9, p.243-243

2018

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Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus

Nature communications, 2015-11, Vol.6 (1), p.8820-8820, Article 8820

2015

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Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation

The Journal of experimental medicine, 2010-04, Vol.207 (4), p.721-730

2010

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Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (9), p.3305-3310

2012

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Activation of Arp2/3 complex-mediated actin polymerization by cortactin

Nature cell biology, 2001-03, Vol.3 (3), p.259-266

2001

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Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration

PloS one, 2012-09, Vol.7 (9), p.e46277-e46277

2012

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Abstract B12: DOCK1 as a novel target for controlling RAS-driven cancer cell survival and invasion

Molecular cancer research, 2020-05, Vol.18 (5_Supplement), p.B12-B12

2020

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A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8

Life science alliance, 2021-04, Vol.4 (4), p.e202000873

2021

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Molecular Basis for Barbed End Uncapping by CARMIL Homology Domain 3 of Mouse CARMIL-1

The Journal of biological chemistry, 2010-09, Vol.285 (37), p.29014-29026

2010

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Sequential Interaction of Actin-related Proteins 2 and 3 (Arp2/3) Complex with Neural Wiscott-Aldrich Syndrome Protein (N-WASP) and Cortactin during Branched Actin Filament Network Formation

The Journal of biological chemistry, 2003-07, Vol.278 (28), p.26086-26093

2003

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Osmotic stress-induced remodeling of the cortical cytoskeleton

American Journal of Physiology: Cell Physiology, 2002-09, Vol.283 (3), p.C850-C865

2002

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The biological function of naturally occurring DOCK2 inhibitor in tissue-specific immune evasion

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.185-185.12

2019

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DOCK family proteins: key players in immune surveillance mechanisms

DOCK8 controls survival of group 3 innate lymphoid cells in the gut through Cdc42 activation

Selective role of neurokinin B in IL-31–induced itch response in mice

Thymic epithelial cell–specific deletion of Jmjd6 reduces Aire protein expression and exacerbates disease development in a mouse model of autoimmune diabetes

The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

Cancer-derived cholesterol sulfate is a key mediator to prevent tumor infiltration by effector T cells

DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer’s Patches

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

Cholesterol sulfate limits neutrophil recruitment and gut inflammation during mucosal injury

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production

Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

Activation of Arp2/3 complex-mediated actin polymerization by cortactin

Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration

Abstract B12: DOCK1 as a novel target for controlling RAS-driven cancer cell survival and invasion

A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8

Molecular Basis for Barbed End Uncapping by CARMIL Homology Domain 3 of Mouse CARMIL-1

Sequential Interaction of Actin-related Proteins 2 and 3 (Arp2/3) Complex with Neural Wiscott-Aldrich Syndrome Protein (N-WASP) and Cortactin during Branched Actin Filament Network Formation

Osmotic stress-induced remodeling of the cortical cytoskeleton

The biological function of naturally occurring DOCK2 inhibitor in tissue-specific immune evasion

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