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Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics

Drug metabolism and pharmacokinetics, 2021-04, Vol.37, p.100373-100373, Article 100373

2021

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jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population

Nucleic acids research, 2021-01, Vol.49 (D1), p.D536

2021

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Molecular basis for the disruption of Keap1-Nrf2 interaction via Hinge & Latch mechanism

Communications biology, 2021-05, Vol.4 (1), p.576-576, Article 576

2021

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Phosphatidylinositol monophosphate-binding interface in the oomycete RXLR effector AVR3a is required for its stability in host cells to modulate plant immunity

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (35), p.14682-14687

2011

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Amino-acid selective isotope labeling enables simultaneous overlapping signal decomposition and information extraction from NMR spectra

Journal of biomolecular NMR, 2020-03, Vol.74 (2-3), p.125-137

2020

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Machine learning approaches to predict gestational age in normal and complicated pregnancies via urinary metabolomics analysis

Scientific reports, 2021-09, Vol.11 (1), p.17777-17777, Article 17777

2021

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Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank

Journal of human genetics, 2023-02, Vol.68 (2), p.55-64

2023

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Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery

PloS one, 2016-08, Vol.11 (8), p.e0160555-e0160555

2016

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Esterification promotes the intracellular accumulation of roxadustat, an activator of hypoxia-inducible factors, to extend its effective duration

Biochemical pharmacology, 2022-03, Vol.197, p.114939-114939, Article 114939

2022

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Global Proteomics for Identifying the Alteration Pathway of Niemann–Pick Disease Type C Using Hepatic Cell Models

International journal of molecular sciences, 2023-10, Vol.24 (21), p.15642

2023

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Biallelic GALM pathogenic variants cause a novel type of galactosemia

Genetics in medicine, 2019-06, Vol.21 (6), p.1286-1294

2019

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A practical method for cell-free protein synthesis to avoid stable isotope scrambling and dilution

Analytical biochemistry, 2011-04, Vol.411 (2), p.223-229

2011

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Identification of novel biomarkers of hepatocellular carcinoma by high‐definition mass spectrometry: Ultrahigh‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry and desorption electrospray ionization mass spectrometry imaging

Rapid communications in mass spectrometry, 2020-04, Vol.34 (S1), p.e8551-n/a

2020

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Effect of Nicotinamide Mononucleotide Concentration in Human Milk on Neurodevelopmental Outcome: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study

Nutrients, 2023-12, Vol.16 (1), p.145

2023

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Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project

Genes to cells : devoted to molecular & cellular mechanisms, 2018-06, Vol.23 (6), p.406-417

2018

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Metabolic Profiling of the Cerebrospinal Fluid in Pediatric Epilepsy

Acta medica Okayama, 2020-02, Vol.74 (1), p.65-72

2020

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Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia

Biological and Pharmaceutical Bulletin, 2021/06/01, Vol.44(6), pp.804-815

2021

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Improved metabolomic data-based prediction of depressive symptoms using nonlinear machine learning with feature selection

Translational psychiatry, 2020-05, Vol.10 (1), p.157-157, Article 157

2020

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Wide-Targeted Metabolome Analysis Identifies Potential Biomarkers for Prognosis Prediction of Epithelial Ovarian Cancer

Toxins, 2021-06, Vol.13 (7), p.461

2021

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KUJIRA, a package of integrated modules for systematic and interactive analysis of NMR data directed to high-throughput NMR structure studies

Journal of biomolecular NMR, 2007-09, Vol.39 (1), p.31-52

2007

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Metabolomic changes in the mouse retina after optic nerve injury

Scientific reports, 2018-08, Vol.8 (1), p.11930-13, Article 11930

2018

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Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals

Human genetics, 2019-04, Vol.138 (4), p.389-409

2019

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Nrf2 plays a critical role in the metabolic response during and after spaceflight

Communications biology, 2021-12, Vol.4 (1), p.1381-1381, Article 1381

2021

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Transcription factor c-Maf deletion improves streptozotocin-induced diabetic nephropathy by directly regulating Sglt2 and Glut2

JCI insight, 2023-03, Vol.8 (6)

2023

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Role of the ENTH Domain in Phosphatidylinositol-4,5-Bisphosphate Binding and Endocytosis

Science (American Association for the Advancement of Science), 2001-02, Vol.291 (5506), p.1047-1051

2001

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Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics

jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population

Molecular basis for the disruption of Keap1-Nrf2 interaction via Hinge & Latch mechanism

Phosphatidylinositol monophosphate-binding interface in the oomycete RXLR effector AVR3a is required for its stability in host cells to modulate plant immunity

Amino-acid selective isotope labeling enables simultaneous overlapping signal decomposition and information extraction from NMR spectra

Machine learning approaches to predict gestational age in normal and complicated pregnancies via urinary metabolomics analysis

Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank

Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery

Esterification promotes the intracellular accumulation of roxadustat, an activator of hypoxia-inducible factors, to extend its effective duration

Global Proteomics for Identifying the Alteration Pathway of Niemann–Pick Disease Type C Using Hepatic Cell Models

Biallelic GALM pathogenic variants cause a novel type of galactosemia

A practical method for cell-free protein synthesis to avoid stable isotope scrambling and dilution

Identification of novel biomarkers of hepatocellular carcinoma by high‐definition mass spectrometry: Ultrahigh‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry and desorption electrospray ionization mass spectrometry imaging

Effect of Nicotinamide Mononucleotide Concentration in Human Milk on Neurodevelopmental Outcome: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study

Omics research project on prospective cohort studies from the Tohoku Medical Megabank Project

Metabolic Profiling of the Cerebrospinal Fluid in Pediatric Epilepsy

Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia

Improved metabolomic data-based prediction of depressive symptoms using nonlinear machine learning with feature selection

Wide-Targeted Metabolome Analysis Identifies Potential Biomarkers for Prognosis Prediction of Epithelial Ovarian Cancer

KUJIRA, a package of integrated modules for systematic and interactive analysis of NMR data directed to high-throughput NMR structure studies

Metabolomic changes in the mouse retina after optic nerve injury

Estimating carrier frequencies of newborn screening disorders using a whole-genome reference panel of 3552 Japanese individuals

Nrf2 plays a critical role in the metabolic response during and after spaceflight

Transcription factor c-Maf deletion improves streptozotocin-induced diabetic nephropathy by directly regulating Sglt2 and Glut2

Role of the ENTH Domain in Phosphatidylinositol-4,5-Bisphosphate Binding and Endocytosis

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