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7‘-Substituted Benzothiazolothio- and Pyridinothiazolothio-Purines as Potent Heat Shock Protein 90 Inhibitors

Journal of medicinal chemistry, 2006-08, Vol.49 (17), p.5352-5362

2006

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Bexarotene metabolism in rat, dog, and human, synthesis of oxidative metabolites, and in vitro activity at retinoid receptors

Drug metabolism and disposition, 2001-07, Vol.29 (7), p.990

2001

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A Phase I Study of LGD1069 in Adults with Advanced Cancer

Clinical cancer research, 1999-07, Vol.5 (7), p.1658-1664

1999

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Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analog inhibitors containing a novel analog of statine

Journal of medicinal chemistry, 1985-12, Vol.28 (12), p.1779-1790

1985

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Pharmacokinetics of 9-cis-retinoic acid in the rhesus monkey

Cancer research (Chicago, Ill.), 1995-02, Vol.55 (3), p.482-485

1995

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Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Correlation between retinoic acid receptor/retinoid x receptor selectivity and effects on metabolic enzymes

Drug metabolism and disposition, 1998-03, Vol.26 (3), p.234

1998

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Initial clinical trial of the retinoid receptor pan agonist 9-cis retinoic acid

Clinical cancer research, 1996-03, Vol.2 (3), p.471-475

1996

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Renin inhibitors. Statine-containing tetrapeptides with varied hydrophobic carboxy termini

Journal of medicinal chemistry, 1987-10, Vol.30 (10), p.1853-1857

1987

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Phase I study of 9-cis-retinoic acid (ALRT1057 capsules) in adults with advanced cancer

Clinical cancer research, 1998-06, Vol.4 (6), p.1437-1442

1998

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A uniquely potent renin inhibitor and its unanticipated plasma binding component

Journal of medicinal chemistry, 1985-12, Vol.28 (12), p.1755-1756

1985

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Oxidative and reductive metabolism of 9-cis-retinoic acid in the rat. Identification of 13,14-dihydro-9-cis-retinoic acid and its taurine conjugate

Drug metabolism and disposition, 1996-03, Vol.24 (3), p.293

1996

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Angiotensin-converting enzyme inhibitors: synthesis and biological activity of acyltripeptide analogs of enalapril

Journal of medicinal chemistry, 1985-04, Vol.28 (4), p.434-442

1985

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Role of Oleate in the Regulation of "Neutral" Rabbit Liver Fructose 1,6-Diphosphatase Activity

The Journal of biological chemistry, 1973-08, Vol.248 (16), p.5555-5561

1973

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Enalapril Maleate (MK-421), a Potent, Nonsulfhydryl Angiotensin-Converting Enzyme Inhibitor: Absorption, Disposition, and Metabolism in Man

Drug metabolism reviews, 1983, Vol.14 (1), p.99-110

Ulm, Edgar H.

1983

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Conformationally restricted inhibitors of angiotensin-converting enzyme. Synthesis and computations

Journal of medicinal chemistry, 1986-02, Vol.29 (2), p.251-260

1986

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Renin inhibitors containing hydrophilic groups. Tetrapeptides with enhanced aqueous solubility and nanomolar potency

Journal of medicinal chemistry, 1988-10, Vol.31 (10), p.1918-1923

1988

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Phosphorus-Containing Inhibitors of Angiotensin-Converting Enzyme

Proceedings of the National Academy of Sciences - PNAS, 1982-04, Vol.79 (7), p.2176-2180

1982

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Angiotensin-converting enzyme inhibitors: synthesis and biological activity of acyl tripeptide analogues of enalapril

Journal of medicinal chemistry, 1985-01, Vol.28 (4), p.434-442

1985

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Quantitative determination of L-364,718, a novel cholecystokinin antagonist, by solid-phase extraction and high-performance liquid chromatography

Journal of Chromatography A, 1988, Vol.437 (2), p.442-446

1988

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STUDIES ON THE ALLOSTERIC ENZYME ALPHA-ISOPROPYLMALATE SYNTHASE

ULM, EDGAR H

1972

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Lisinopril

Cardiovascular drug reviews, 1988-09, Vol.6 (3), p.181-191

1988

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Enalapril

Cardiovascular drug reviews, 1984-03, Vol.2 (1), p.1-17

1984

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Design of proteolytically-stable, peptidal renin inhibitors and determination of their fate in vivo

Regulatory peptides, 1985, Vol.10, p.8-13

1985

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Renin inhibitors containing 2-substituted statine

Biochemical Society transactions, 1984-12, Vol.12 (6), p.956-959

1984

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[60] Fructose-1,6-diphosphatase from rabbit liver

Methods in Enzymology, 1975, Vol.42, p.369-374

1975

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7‘-Substituted Benzothiazolothio- and Pyridinothiazolothio-Purines as Potent Heat Shock Protein 90 Inhibitors

Bexarotene metabolism in rat, dog, and human, synthesis of oxidative metabolites, and in vitro activity at retinoid receptors

A Phase I Study of LGD1069 in Adults with Advanced Cancer

Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analog inhibitors containing a novel analog of statine

Pharmacokinetics of 9-cis-retinoic acid in the rhesus monkey

Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Correlation between retinoic acid receptor/retinoid x receptor selectivity and effects on metabolic enzymes

Initial clinical trial of the retinoid receptor pan agonist 9-cis retinoic acid

Renin inhibitors. Statine-containing tetrapeptides with varied hydrophobic carboxy termini

Phase I study of 9-cis-retinoic acid (ALRT1057 capsules) in adults with advanced cancer

A uniquely potent renin inhibitor and its unanticipated plasma binding component

Oxidative and reductive metabolism of 9-cis-retinoic acid in the rat. Identification of 13,14-dihydro-9-cis-retinoic acid and its taurine conjugate

Angiotensin-converting enzyme inhibitors: synthesis and biological activity of acyltripeptide analogs of enalapril

Role of Oleate in the Regulation of "Neutral" Rabbit Liver Fructose 1,6-Diphosphatase Activity

Enalapril Maleate (MK-421), a Potent, Nonsulfhydryl Angiotensin-Converting Enzyme Inhibitor: Absorption, Disposition, and Metabolism in Man

Conformationally restricted inhibitors of angiotensin-converting enzyme. Synthesis and computations

Renin inhibitors containing hydrophilic groups. Tetrapeptides with enhanced aqueous solubility and nanomolar potency

Phosphorus-Containing Inhibitors of Angiotensin-Converting Enzyme

Angiotensin-converting enzyme inhibitors: synthesis and biological activity of acyl tripeptide analogues of enalapril

Quantitative determination of L-364,718, a novel cholecystokinin antagonist, by solid-phase extraction and high-performance liquid chromatography

STUDIES ON THE ALLOSTERIC ENZYME ALPHA-ISOPROPYLMALATE SYNTHASE

Lisinopril

Enalapril

Design of proteolytically-stable, peptidal renin inhibitors and determination of their fate in vivo

Renin inhibitors containing 2-substituted statine

[60] Fructose-1,6-diphosphatase from rabbit liver

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