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2′-O-Methyl at 20-mer Guide Strand 3′ Termini May Negatively Affect Target Silencing Activity of Fully Chemically Modified siRNA

Molecular therapy. Nucleic acids, 2020-09, Vol.21, p.266-277

2020

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5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

Nucleic acids research, 2017-07, Vol.45 (13), p.7581

2017

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5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

Nucleic acids research, 2017-07, Vol.45 (13), p.7581-7592

2017

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Abstract 12705: Identification and Characterization of Solbinsiran, a GalNAc Conjugated siRNA Targeting Angiopoietin-Like 3

Circulation (New York, N.Y.), 2023-11, Vol.148 (Suppl_1)

2023

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Adaptations to a Subterranean Environment and Longevity Revealed by the Analysis of Mole Rat Genomes

Cell reports (Cambridge), 2014-09, Vol.8 (5), p.1354-1364

2014

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Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage

RNA (Cambridge), 2014-07, Vol.20 (7), p.1023-1034

2014

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Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage

RNA (Cambridge), 2014-10, Vol.20 (10), p.1653-1653

2014

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Analyses of Fruit Flies That Do Not Express Selenoproteins or Express the Mouse Selenoprotein, Methionine Sulfoxide Reductase B1, Reveal a Role of Selenoproteins in Stress Resistance

The Journal of biological chemistry, 2011-08, Vol.286 (34), p.29449-29461

2011

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Antibiotics induce mistranslation of selenocysteine residue in selenoproteins

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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Biosynthesis of Selenocysteine, the 21st Amino Acid in the Genetic Code, and a Novel Pathway for Cysteine Biosynthesis

Advances in nutrition (Bethesda, Md.), 2011-03, Vol.2 (2), p.122-128

2011

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Biosynthesis of Selenocysteine, the 21st Amino Acid in the Genetic Code, and a Novel Pathway for Cysteine Biosynthesis12

Advances in nutrition (Bethesda, Md.), 2011-03, Vol.2 (2), p.122-128

2011

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The central role of selenium in the biochemistry and ecology of the harmful pelagophyte, Aureococcus anophagefferens

The ISME Journal, 2013-07, Vol.7 (7), p.1333-1343

2013

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The central role of selenium in the biochemistry and ecology of the harmful pelagophyte, Aureococcus anophagefferens

The ISME Journal, 2013-03, Vol.7 (7)

2013

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Characterization of Alternative Cytosolic Forms and Cellular Targets of Mouse Mitochondrial Thioredoxin Reductase

The Journal of biological chemistry, 2006-08, Vol.281 (32), p.22953-22963

2006

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Characterization of Protein Targets of Mammalian Thioredoxin Reductases

Methods in Enzymology, 2010, Vol.474, p.245-254

2010

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Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1

Molecular therapy. Nucleic acids, 2022-09, Vol.29, p.135-149

2022

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Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

Nucleic acids research, 2018-03, Vol.46 (5), p.2185-2196

2018

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Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis

Carcinogenesis (New York), 2013-05, Vol.34 (5), p.1089-1095

2013

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Crystal Structures of Oxidized and Reduced Mitochondrial Thioredoxin Reductase Provide Molecular Details of the Reaction Mechanism

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (42), p.15018-15023

2005

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Dual functions of codons in the genetic code

Critical reviews in biochemistry and molecular biology, 2010-08, Vol.45 (4), p.257-265

2010

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The Euplotes crassus selenoproteome

The FASEB journal, 2009-04, Vol.23 (S1)

2009

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Gene expression defines natural changes in mammalian lifespan

Aging cell, 2015-06, Vol.14 (3), p.352-365

2015

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Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon

Science (American Association for the Advancement of Science), 2009-01, Vol.323 (5911), p.259-261

2009

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Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii

Nature communications, 2013-08, Vol.4 (1), p.2212-2212, Article 2212

2013

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2′-O-Methyl at 20-mer Guide Strand 3′ Termini May Negatively Affect Target Silencing Activity of Fully Chemically Modified siRNA

5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

Abstract 12705: Identification and Characterization of Solbinsiran, a GalNAc Conjugated siRNA Targeting Angiopoietin-Like 3

Adaptations to a Subterranean Environment and Longevity Revealed by the Analysis of Mole Rat Genomes

Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage

Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage

Analyses of Fruit Flies That Do Not Express Selenoproteins or Express the Mouse Selenoprotein, Methionine Sulfoxide Reductase B1, Reveal a Role of Selenoproteins in Stress Resistance

Antibiotics induce mistranslation of selenocysteine residue in selenoproteins

Biosynthesis of Selenocysteine, the 21st Amino Acid in the Genetic Code, and a Novel Pathway for Cysteine Biosynthesis

Biosynthesis of Selenocysteine, the 21st Amino Acid in the Genetic Code, and a Novel Pathway for Cysteine Biosynthesis12

The central role of selenium in the biochemistry and ecology of the harmful pelagophyte, Aureococcus anophagefferens

The central role of selenium in the biochemistry and ecology of the harmful pelagophyte, Aureococcus anophagefferens

Characterization of Alternative Cytosolic Forms and Cellular Targets of Mouse Mitochondrial Thioredoxin Reductase

Characterization of Protein Targets of Mammalian Thioredoxin Reductases

Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis

Crystal Structures of Oxidized and Reduced Mitochondrial Thioredoxin Reductase Provide Molecular Details of the Reaction Mechanism

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

Dual functions of codons in the genetic code

The Euplotes crassus selenoproteome

Gene expression defines natural changes in mammalian lifespan

Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon

Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii

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