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Bioorthogonal Chemistry for Site-Specific Labeling and Surface Immobilization of Proteins

Accounts of chemical research, 2011-09, Vol.44 (9), p.762-773

2011

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Palmitoylation as a Key Regulator of Ras Localization and Function

Frontiers in molecular biosciences, 2021-03, Vol.8, p.659861-659861

2021

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Identification of benzo[cd]indol-2(1H)-ones as novel Atg4B inhibitors via a structure-based virtual screening and a novel AlphaScreen assay

European journal of medicinal chemistry, 2019-09, Vol.178, p.648-666

2019

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High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.343-348

2023

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Influence of the Lipidation Motif on the Partitioning and Association of N-Ras in Model Membrane Subdomains

Journal of the American Chemical Society, 2009-02, Vol.131 (4), p.1557-1564

2009

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Revealing conformational substates of lipidated N-Ras protein by pressure modulation

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (2), p.460-465

2012

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Membrane-Mediated Induction and Sorting of K-Ras Microdomain Signaling Platforms

Journal of the American Chemical Society, 2011-02, Vol.133 (4), p.880-887

2011

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Highly Efficient Strategy for Modification of Proteins at the C Terminus

Angewandte Chemie (International ed.), 2010-12, Vol.49 (49), p.9417-9421

2010

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Semisynthetic Lipidated LC3 Protein Mediates Membrane Fusion

Chembiochem : a European journal of chemical biology, 2013-07, Vol.14 (11), p.1296-1300

2013

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Chemical tools for modulating autophagy

Tetrahedron, 2015-01, Vol.71 (3), p.387-406

Triola, Gemma

2015

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High Affinity Immobilization of Proteins Using the CrAsH/TC Tag

Molecules (Basel, Switzerland), 2016-06, Vol.21 (6), p.750-750

2016

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Chemical-Biological Exploration of the Limits of the Ras De- and Repalmitoylating Machinery

Chembiochem : a European journal of chemical biology, 2012-05, Vol.13 (7), p.1017-1023

2012

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Specificity of the Dihydroceramide Desaturase Inhibitor N-[(1R,2S)-2-Hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl]octanamide (GT11) in Primary Cultured Cerebellar Neurons

Molecular pharmacology, 2004-12, Vol.66 (6), p.1671-1678

2004

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Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

Nature (London), 2013-05, Vol.497 (7451), p.638-642

2013

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N-Ras Forms Dimers at POPC Membranes

Biophysical journal, 2012-10, Vol.103 (7), p.1585-1593

2012

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A hydroxylamine probe for profiling S-acylated fatty acids on proteins

Chemical communications (Cambridge, England), 2019-09, Vol.55 (75), p.11183-11186

2019

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Chemical Biology of Lipidated Proteins

ACS chemical biology, 2012-01, Vol.7 (1), p.87-99

2012

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Dinuclear silver and gold bisNHC complexes as drug candidates for cancer therapy

Bioorganic & medicinal chemistry, 2022-08, Vol.67, p.116814-116814, Article 116814

2022

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Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

Nature chemical biology, 2011-10, Vol.7 (12), p.942

2011

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Quantitative analysis of protein lipidation and acyl-CoAs reveals substrate preferences of the S -acylation machinery

Chemical science (Cambridge), 2024

2024

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Racemization-Free Synthesis of S-Alkylated Cysteines via Thiol-ene Reaction

Journal of organic chemistry, 2008-05, Vol.73 (9), p.3646-3649

2008

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Azide-tagged sphingolipids for the proteome-wide identification of C16-ceramide-binding proteins

Chemical communications (Cambridge, England), 2018-12, Vol.54 (97), p.13742-13745

2018

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Structure Guided Design and Kinetic Analysis of Highly Potent Benzimidazole Inhibitors Targeting the PDEδ Prenyl Binding Site

Journal of medicinal chemistry, 2014-06, Vol.57 (12), p.5435-5448

2014

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Activity-Based Imaging of Acid Ceramidase in Living Cells

Journal of the American Chemical Society, 2019-05, Vol.141 (19), p.7736-7742

2019

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The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction

European biophysics journal, 2012-10, Vol.41 (10), p.801-813

2012

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Bioorthogonal Chemistry for Site-Specific Labeling and Surface Immobilization of Proteins

Palmitoylation as a Key Regulator of Ras Localization and Function

Identification of benzo[cd]indol-2(1H)-ones as novel Atg4B inhibitors via a structure-based virtual screening and a novel AlphaScreen assay

High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase

Influence of the Lipidation Motif on the Partitioning and Association of N-Ras in Model Membrane Subdomains

Revealing conformational substates of lipidated N-Ras protein by pressure modulation

Membrane-Mediated Induction and Sorting of K-Ras Microdomain Signaling Platforms

Highly Efficient Strategy for Modification of Proteins at the C Terminus

Semisynthetic Lipidated LC3 Protein Mediates Membrane Fusion

Chemical tools for modulating autophagy

High Affinity Immobilization of Proteins Using the CrAsH/TC Tag

Chemical-Biological Exploration of the Limits of the Ras De- and Repalmitoylating Machinery

Specificity of the Dihydroceramide Desaturase Inhibitor N-[(1R,2S)-2-Hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl]octanamide (GT11) in Primary Cultured Cerebellar Neurons

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

N-Ras Forms Dimers at POPC Membranes

A hydroxylamine probe for profiling S-acylated fatty acids on proteins

Chemical Biology of Lipidated Proteins

Dinuclear silver and gold bisNHC complexes as drug candidates for cancer therapy

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

Quantitative analysis of protein lipidation and acyl-CoAs reveals substrate preferences of the S -acylation machinery

Racemization-Free Synthesis of S-Alkylated Cysteines via Thiol-ene Reaction

Azide-tagged sphingolipids for the proteome-wide identification of C16-ceramide-binding proteins

Structure Guided Design and Kinetic Analysis of Highly Potent Benzimidazole Inhibitors Targeting the PDEδ Prenyl Binding Site

Activity-Based Imaging of Acid Ceramidase in Living Cells

The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction

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