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Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.15960-15976

2023

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Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo

The Journal of biological chemistry, 2015-08, Vol.290 (33), p.20044-20059

2015

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A Highly Selective Hydantoin Inhibitor of Aggrecanase‑1 and Aggrecanase‑2 with a Low Projected Human Dose

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5933-5939

2017

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Identification of Potent and Selective Hydantoin Inhibitors of Aggrecanase‑1 and Aggrecanase‑2 That Are Efficacious in Both Chemical and Surgical Models of Osteoarthritis

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10476-10485

2014

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Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models

Scientific reports, 2018-10, Vol.8 (1), p.15458-12, Article 15458

2018

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Use of Osmotic Pumps to Establish the Pharmacokinetic–Pharmacodynamic Relationship and Define Desirable Human Performance Characteristics for Aggrecanase Inhibitors

Journal of medicinal chemistry, 2016-06, Vol.59 (12), p.5810-5822

2016

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A novel achiral seco-amino-cyclopropylindoline (CI) analog of CC-1065 and the duocarmycins: design, synthesis and biological studies

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2005-01, Vol.1 (1), p.13

2005

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Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (16), p.2245-2248

2002

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Identification of antimicrobial compounds active against intracellular Staphylococcus aureus

FEMS immunology and medical microbiology, 2005-08, Vol.45 (2), p.245-252

2005

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EFFICIENT SYNTHESIS OF (±)-seco-CYCLOPROPANEINDOLINE ANALOGS OF CC-1065

Heterocyclic communications, 2001, Vol.7 (1), p.7-16

2001

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Comparative transcriptomics of convergent evolution: different genes but conserved pathways underlie caste phenotypes across lineages of eusocial insects

Molecular biology and evolution, 2015-03, Vol.32 (3), p.690-703

2015

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Hispanic ethnicity and mortality among critically ill patients with COVID-19

PloS one, 2022-05, Vol.17 (5), p.e0268022-e0268022

2022

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Early Social Attention Impairments in Autism: Social Orienting, Joint Attention, and Attention to Distress

Developmental psychology, 2004-03, Vol.40 (2), p.271-283

2004

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Flame spread: Effects of microgravity and scale

Combustion and flame, 2019-01, Vol.199, p.168-182

2019

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Nourishment level affects caste-related gene expression in Polistes wasps

BMC genomics, 2015-03, Vol.16 (1), p.235-235, Article 235

2015

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A Holistic Perspective on the Dynamics of G035.39-00.33: The Interplay between Gas and Magnetic Fields

The Astrophysical journal, 2018-06, Vol.859 (2), p.151

2018

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Upwelling buffers climate change impacts on coral reefs of the eastern tropical Pacific

Ecology (Durham), 2020-02, Vol.101 (2), p.1-15

2020

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SN 2018zd: an unusual stellar explosion as part of the diverse Type II Supernova landscape

Monthly notices of the Royal Astronomical Society, 2020-10, Vol.498 (1), p.84-100

2020

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Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial

The Lancet (British edition), 2022-12, Vol.400 (10367), p.1927-1937

2022

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Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system

The Journal of cell biology, 2014-03, Vol.204 (7), p.1219-1236

2014

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Planck Cold Clumps in the λ Orionis Complex. II. Environmental Effects on Core Formation

The Astrophysical journal. Supplement series, 2018-06, Vol.236 (2), p.51

2018

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Digital Breast Tomosynthesis Practice Patterns Following 2011 FDA Approval: A Survey of Breast Imaging Radiologists

Academic radiology, 2017-08, Vol.24 (8), p.947-953

2017

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Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor

Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo

A Highly Selective Hydantoin Inhibitor of Aggrecanase‑1 and Aggrecanase‑2 with a Low Projected Human Dose

Identification of Potent and Selective Hydantoin Inhibitors of Aggrecanase‑1 and Aggrecanase‑2 That Are Efficacious in Both Chemical and Surgical Models of Osteoarthritis

Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models

Use of Osmotic Pumps to Establish the Pharmacokinetic–Pharmacodynamic Relationship and Define Desirable Human Performance Characteristics for Aggrecanase Inhibitors

A novel achiral seco-amino-cyclopropylindoline (CI) analog of CC-1065 and the duocarmycins: design, synthesis and biological studies

Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides

Identification of antimicrobial compounds active against intracellular Staphylococcus aureus

EFFICIENT SYNTHESIS OF (±)-seco-CYCLOPROPANEINDOLINE ANALOGS OF CC-1065

Comparative transcriptomics of convergent evolution: different genes but conserved pathways underlie caste phenotypes across lineages of eusocial insects

Hispanic ethnicity and mortality among critically ill patients with COVID-19

Early Social Attention Impairments in Autism: Social Orienting, Joint Attention, and Attention to Distress

Flame spread: Effects of microgravity and scale

Direct Observational Evidence of the Multi-scale, Dynamical Mass Accretion Toward a High-mass Star-forming Hub-filament System

Core lipid, surface lipid and apolipoprotein composition analysis of lipoprotein particles as a function of particle size in one workflow integrating asymmetric flow field-flow fractionation and liquid chromatography-tandem mass spectrometry

Nourishment level affects caste-related gene expression in Polistes wasps

A Holistic Perspective on the Dynamics of G035.39-00.33: The Interplay between Gas and Magnetic Fields

Upwelling buffers climate change impacts on coral reefs of the eastern tropical Pacific

SN 2018zd: an unusual stellar explosion as part of the diverse Type II Supernova landscape

Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial

Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system

Planck Cold Clumps in the λ Orionis Complex. II. Environmental Effects on Core Formation

Digital Breast Tomosynthesis Practice Patterns Following 2011 FDA Approval: A Survey of Breast Imaging Radiologists

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