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The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

Expert review of vaccines, 2013-07, Vol.12 (7), p.809-819

2013

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Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies

Journal for immunotherapy of cancer, 2019-09, Vol.7 (1), p.244-244, Article 244

2019

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Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8

The Journal of immunology (1950), 2005-02, Vol.174 (3), p.1259-1268

2005

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Different adjuvanted pediatric HIV envelope vaccines induced distinct plasma antibody responses despite similar B cell receptor repertoires in infant rhesus macaques

PloS one, 2021-12, Vol.16 (12), p.e0256885-e0256885

2021

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Optimizing a Multi-Component Intranasal Entamoeba Histolytica Vaccine Formulation Using a Design of Experiments Strategy

Frontiers in immunology, 2021-06, Vol.12, p.683157-683157

2021

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Immunogenicity and safety of an Entamoeba histolytica adjuvanted protein vaccine candidate (LecA+GLA-3M-052 liposomes) in rhesus macaques

Human vaccines & immunotherapeutics, 2024-12, Vol.20 (1), p.2374147

2024

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TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth

JCI insight, 2017-03, Vol.2 (6), p.e91020-e91020

2017

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Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists

International immunology, 2006-07, Vol.18 (7), p.1115-1126

2006

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Development of COVID-19 vaccine using a dual Toll-like receptor ligand liposome adjuvant

npj vaccines, 2021-11, Vol.6 (1), p.137-137, Article 137

2021

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Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

Nature (London), 2021-06, Vol.594 (7864), p.553-559

2021

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Adsorption of a synthetic TLR7/8 ligand to aluminum oxyhydroxide for enhanced vaccine adjuvant activity: A formulation approach

Journal of controlled release, 2016-12, Vol.244 (Pt A), p.98-107

2016

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Nanoformulation of synergistic TLR ligands to enhance vaccination against Entamoeba histolytica

Vaccine, 2017-02, Vol.35 (6), p.916-922

2017

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Daily or Weekly Therapy with Resiquimod (R-848) Reduces Genital Recurrences in Herpes Simplex Virus–Infected Guinea Pigs during and after Treatment

The Journal of infectious diseases, 2001-03, Vol.183 (6), p.844-849

2001

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Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors

Oncotarget, 2015-03, Vol.6 (7), p.4663-4676

2015

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A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates

Science immunology, 2021-07, Vol.6 (61)

2021

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TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN

Journal of interferon & cytokine research, 2008-04, Vol.28 (4), p.253

2008

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TLR-7 and -8 agonists as vaccine adjuvants

Expert review of vaccines, 2011-04, Vol.10 (4), p.405-407

2011

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Adjuvant composition and delivery route shape immune response quality and protective efficacy of a recombinant vaccine for Entamoeba histolytica

npj vaccines, 2018-06, Vol.3 (1), p.22-22, Article 22

2018

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Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine

Frontiers in Drug Delivery, 2024-02, Vol.4

2024

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Cytokine induction in mice by the immunomodulator imiquimod

Journal of leukocyte biology, 1994-02, Vol.55 (2), p.234-240

1994

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Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod

Cellular immunology, 2002-07, Vol.218 (1), p.74-86

2002

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Topical Imiquimod Treatment Prevents UV-Light Induced Loss of Contact Hypersensitivity and Immune Tolerance

Journal of investigative dermatology, 2006-04, Vol.126 (4), p.821-831

2006

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Resiquimod and other immune response modifiers as vaccine adjuvants

Expert review of vaccines, 2007-10, Vol.6 (5), p.835-847

2007

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The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies

Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8

Different adjuvanted pediatric HIV envelope vaccines induced distinct plasma antibody responses despite similar B cell receptor repertoires in infant rhesus macaques

Optimizing a Multi-Component Intranasal Entamoeba Histolytica Vaccine Formulation Using a Design of Experiments Strategy

Immunogenicity and safety of an Entamoeba histolytica adjuvanted protein vaccine candidate (LecA+GLA-3M-052 liposomes) in rhesus macaques

TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth

Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists

Development of COVID-19 vaccine using a dual Toll-like receptor ligand liposome adjuvant

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

Adsorption of a synthetic TLR7/8 ligand to aluminum oxyhydroxide for enhanced vaccine adjuvant activity: A formulation approach

Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection

Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction

Nanoformulation of synergistic TLR ligands to enhance vaccination against Entamoeba histolytica

Daily or Weekly Therapy with Resiquimod (R-848) Reduces Genital Recurrences in Herpes Simplex Virus–Infected Guinea Pigs during and after Treatment

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors

A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates

TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN

TLR-7 and -8 agonists as vaccine adjuvants

Adjuvant composition and delivery route shape immune response quality and protective efficacy of a recombinant vaccine for Entamoeba histolytica

Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine

Cytokine induction in mice by the immunomodulator imiquimod

Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod

Topical Imiquimod Treatment Prevents UV-Light Induced Loss of Contact Hypersensitivity and Immune Tolerance

Resiquimod and other immune response modifiers as vaccine adjuvants

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