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Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy

Cell stem cell, 2021-12, Vol.28 (12), p.2062-2075.e5

2021

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Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma

Nature communications, 2022-11, Vol.13 (1), p.7341-7341, Article 7341

2022

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Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart

Cell research, 2017-10, Vol.27 (10), p.1195-1215

2017

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A Unique RNA Fold in the RumA-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function

Cell, 2005-03, Vol.120 (5), p.599-611

2005

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iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy

Science translational medicine, 2020-11, Vol.12 (568)

2020

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Dual antigen–targeted off-the-shelf NK cells show durable response and prevent antigen escape in lymphoma and leukemia

Blood, 2022-12, Vol.140 (23), p.2451-2462

2022

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A Single Mutation Traps a Half-Sites Reactive Enzyme in Midstream, Explaining Asymmetry in Hydride Transfer

Biochemistry (Easton), 2018-05, Vol.57 (19), p.2786-2795

2018

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Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (13), p.3562-3569

2007

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The Role of Protein Dynamics in Thymidylate Synthase Catalysis: Variants of Conserved 2‘-Deoxyuridine 5‘-Monophosphate (dUMP)-Binding Tyr-261

Biochemistry (Easton), 2006-06, Vol.45 (24), p.7415-7428

2006

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Crystal Structure of RumA, an Iron-Sulfur Cluster Containing E. coli Ribosomal RNA 5-Methyluridine Methyltransferase

Structure (London), 2004-03, Vol.12 (3), p.397-407

2004

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KLYP956 Is a Non-Imidazole-Based Orally Active Inhibitor of Nitric-Oxide Synthase Dimerization

Molecular pharmacology, 2009-07, Vol.76 (1), p.153-162

2009

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Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m⁵U methyltransferases

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.6876-6881

2008

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A chemical approach facilitates CRISPRa-only human iPSC generation and minimizes the number of targeted loci required

Future science OA, 2024-01, Vol.10 (1), p.FSO964

2024

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A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors

Med (New York, N.Y. : Online), 2023-07, Vol.4 (7), p.457-477.e8

2023

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A Single Mutation Traps a Half-sites Reactive Enzyme in Mid-stream, Explaining Asymmetry in Hydride Transfer

Biochemistry (Easton), 2018-05, Vol.57 (19), p.2786-2795

2018

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Abstract 1539: Development of off-the-shelf B7H3 chimeric antigen receptor NK cell therapeutic with broad applicability across many solid tumors

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1539-1539

2021

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Abstract 3574: Cytokine-autonomous, CAR-directed, off-the-shelf natural killer cells derived from a clonal engineered master pluripotent cell line

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3574-3574

2018

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Effects of Subunit Occupancy on Partitioning of an Intermediate in Thymidylate Synthase Mutants

Biochemistry (Easton), 2000-03, Vol.39 (10), p.2429-2435

2000

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Abstract 1138: Detection of genetically engineered iPSC-derived natural killer cells in blood and tissue

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1138-1138

2022

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His68 and His141 Are Critical Contributors to the Intersubunit Catalytic Site of Adenylosuccinate Lyase of Bacillus subtilis

Biochemistry (Easton), 1999-01, Vol.38 (1), p.22-32

1999

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Implication of His68 in the Substrate Site of Bacillus subtilis Adenylosuccinate Lyase by Mutagenesis and Affinity Labeling with 2-[(4-Bromo-2,3-dioxobutyl)thio]adenosine 5‘-monophosphate

Biochemistry (Easton), 1998-06, Vol.37 (23), p.8481-8489

1998

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Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m^sup 5^U methyltransferases

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.6876

2008

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Structure of a TrmA–RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m 5 U methyltransferases

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.6876-6881

2008

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Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m super(5)U methyltransferases

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.6876-6881

2008

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The role of protein dynamics in thymidylate synthase catalysis: Variants of conserved dUMP-binding Tyr-261

Biochemistry (Easton), 2006-06, Vol.45 (24), p.7415-7428

2006

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