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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

Experimental biology and medicine (Maywood, N.J.), 2003-02, Vol.228 (2), p.111-133

2003

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HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

Molecular cell, 2005-05, Vol.18 (5), p.601-607

2005

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FKBP51 Promotes Assembly of the Hsp90 Chaperone Complex and Regulates Androgen Receptor Signaling in Prostate Cancer Cells

Molecular and Cellular Biology, 2010-03, Vol.30 (5), p.1243-1253

2010

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Up-regulation of heat shock protein 27 induces resistance to 17-allylamino-demethoxygeldanamycin through a glutathione-mediated mechanism

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (22), p.10967-10975

2006

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An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Molecular cell, 2007-01, Vol.25 (1), p.151-159

2007

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Phase I Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients With Advanced Cancer

Journal of clinical oncology, 2005-02, Vol.23 (6), p.1078-1087

2005

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Requirement of Heat Shock Protein 90 for Human Hepatitis B Virus Reverse Transcriptase Function

Journal of Virology, 2004-12, Vol.78 (23), p.13122-13131

2004

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The Assembly and Intermolecular Properties of the hsp70-Hop-hsp90 Molecular Chaperone Complex

The Journal of biological chemistry, 2002-10, Vol.277 (41), p.38294-38304

2002

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A Phase I Trial of Twice-Weekly 17-Allylamino-Demethoxy-Geldanamycin in Patients with Advanced Cancer

Clinical cancer research, 2006-10, Vol.12 (20), p.6087-6093

2006

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P-Glycoprotein-Mediated Resistance to Hsp90-Directed Therapy Is Eclipsed by the Heat Shock Response

Cancer research (Chicago, Ill.), 2008-09, Vol.68 (18), p.7419-7427

2008

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Hsp90 Inhibition Depletes Chk1 and Sensitizes Tumor Cells to Replication Stress

The Journal of biological chemistry, 2003-12, Vol.278 (52), p.52572-52577

2003

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Defining the Requirements for Hsp40 and Hsp70 in the Hsp90 Chaperone Pathway

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26235-26244

2006

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GCUNC45 Is the First Hsp90 Co-chaperone to Show α/β Isoform Specificity

The Journal of biological chemistry, 2008-04, Vol.283 (15), p.9509-9512

2008

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Cisplatin abrogates the geldanamycin-induced heat shock response

Molecular cancer therapeutics, 2008-10, Vol.7 (10), p.3256-3264

2008

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Molecular Chaperones Function as Steroid Receptor Nuclear Mobility Factors

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.2876-2881

2004

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Chaperoning Checkpoint Kinase 1 (Chk1), an Hsp90 Client, with Purified Chaperones

The Journal of biological chemistry, 2006-02, Vol.281 (5), p.2989-2998

2006

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HSP40 Binding Is the First Step in the HSP90 Chaperoning Pathway for the Progesterone Receptor

The Journal of biological chemistry, 2002-04, Vol.277 (14), p.11873-11881

2002

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Molecular Chaperone Machines: Chaperone Activities of the Cyclophilin Cyp-40 and the Steroid Aporeceptor-Associated Protein p23

Science (American Association for the Advancement of Science), 1996-12, Vol.274 (5293), p.1718-1720

1996

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The Influence of ATP and p23 on the Conformation of hsp90

The Journal of biological chemistry, 2002-11, Vol.277 (48), p.45942-45948

2002

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Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids

The EMBO journal, 1997-01, Vol.16 (1), p.59-68

1997

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Phase I study of 17-allylamino-17 demethoxygeldanamycin, gemcitabine and/or cisplatin in patients with refractory solid tumors

Investigational new drugs, 2011-06, Vol.29 (3), p.473-480

2011

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Structures of the N-Terminal and Middle Domains of E. coli Hsp90 and Conformation Changes upon ADP Binding

Structure (London), 2005-04, Vol.13 (4), p.579-590

2005

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p23, a simple protein with complex activities

Cell stress & chaperones, 2003, Vol.8 (2), p.108-113

2003

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The Assembly of Progesterone Receptor-hsp90 Complexes Using Purified Proteins

The Journal of biological chemistry, 1998-12, Vol.273 (49), p.32973-32979

1998

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The hsp90-related Protein TRAP1 Is a Mitochondrial Protein with Distinct Functional Properties

The Journal of biological chemistry, 2000-02, Vol.275 (5), p.3305-3312

2000

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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

FKBP51 Promotes Assembly of the Hsp90 Chaperone Complex and Regulates Androgen Receptor Signaling in Prostate Cancer Cells

Up-regulation of heat shock protein 27 induces resistance to 17-allylamino-demethoxygeldanamycin through a glutathione-mediated mechanism

An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Phase I Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients With Advanced Cancer

Requirement of Heat Shock Protein 90 for Human Hepatitis B Virus Reverse Transcriptase Function

The Assembly and Intermolecular Properties of the hsp70-Hop-hsp90 Molecular Chaperone Complex

A Phase I Trial of Twice-Weekly 17-Allylamino-Demethoxy-Geldanamycin in Patients with Advanced Cancer

P-Glycoprotein-Mediated Resistance to Hsp90-Directed Therapy Is Eclipsed by the Heat Shock Response

Hsp90 Inhibition Depletes Chk1 and Sensitizes Tumor Cells to Replication Stress

Defining the Requirements for Hsp40 and Hsp70 in the Hsp90 Chaperone Pathway

GCUNC45 Is the First Hsp90 Co-chaperone to Show α/β Isoform Specificity

Cisplatin abrogates the geldanamycin-induced heat shock response

Molecular Chaperones Function as Steroid Receptor Nuclear Mobility Factors

Chaperoning Checkpoint Kinase 1 (Chk1), an Hsp90 Client, with Purified Chaperones

HSP40 Binding Is the First Step in the HSP90 Chaperoning Pathway for the Progesterone Receptor

Molecular Chaperone Machines: Chaperone Activities of the Cyclophilin Cyp-40 and the Steroid Aporeceptor-Associated Protein p23

The Influence of ATP and p23 on the Conformation of hsp90

Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids

Phase I study of 17-allylamino-17 demethoxygeldanamycin, gemcitabine and/or cisplatin in patients with refractory solid tumors

Structures of the N-Terminal and Middle Domains of E. coli Hsp90 and Conformation Changes upon ADP Binding

p23, a simple protein with complex activities

The Assembly of Progesterone Receptor-hsp90 Complexes Using Purified Proteins

The hsp90-related Protein TRAP1 Is a Mitochondrial Protein with Distinct Functional Properties

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