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A Journey towards Understanding the Molecular Pathology and Developing Therapies for Lysosomal Storage Disorders

Cells (Basel, Switzerland), 2021-12, Vol.11 (1), p.36

Tikkanen, Ritva

2021

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Validation of Aspartylglucosaminidase Activity Assay for Human Serum Samples: Establishment of a Biomarker for Diagnostics and Clinical Studies

International journal of molecular sciences, 2023-03, Vol.24 (6), p.5722

2023

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Endocytic trafficking of membrane-bound cargo: a flotillin point of view

Membranes (Basel), 2014-07, Vol.4 (3), p.356-371

2014

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Mitogen-Activated Protein Kinases: Functions in Signal Transduction and Human Diseases

International journal of molecular sciences, 2019-09, Vol.20 (19), p.4844

2019

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Dissecting the molecular function of reggie/flotillin proteins

European journal of cell biology, 2007-09, Vol.86 (9), p.525-532

2007

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Flotillin-1/Reggie-2 Protein Plays Dual Role in Activation of Receptor-tyrosine Kinase/Mitogen-activated Protein Kinase Signaling

The Journal of biological chemistry, 2012-03, Vol.287 (10), p.7265-7278

2012

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Towards Splicing Therapy for Lysosomal Storage Disorders: Methylxanthines and Luteolin Ameliorate Splicing Defects in Aspartylglucosaminuria and Classic Late Infantile Neuronal Ceroid Lipofuscinosis

Cells (Basel, Switzerland), 2021-10, Vol.10 (11), p.2813

2021

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Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount

International Journal of Molecular Sciences, 2013-03, Vol.14 (3), p.4854-4884

2013

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Human Desmocollin 3‒Specific IgG Antibodies Are Pathogenic in a Humanized HLA Class II Transgenic Mouse Model of Pemphigus

Journal of investigative dermatology, 2022-03, Vol.142 (3), p.915-923.e3

2022

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Dsg3 epitope-specific signalling in pemphigus

Frontiers in immunology, 2023-04, Vol.14, p.1163066

2023

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Editorial: Pharmacology of gangliosides

Frontiers in pharmacology, 2024-07, Vol.15, p.1449928

2024

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Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris

International journal of molecular sciences, 2019-06, Vol.20 (13), p.3113

2019

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Random Splicing of Several Exons Caused by a Single Base Change in the Target Exon of CRISPR/Cas9 Mediated Gene Knockout

Cells (Basel, Switzerland), 2016-12, Vol.5 (4), p.45-45

2016

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Regulation of ubiquitin-binding proteins by monoubiquitination

Nature cell biology, 2006-02, Vol.8 (2), p.163-169

2006

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Identification of structural elements in Nox1 and Nox4 controlling localization and activity

Antioxidants & redox signaling, 2009-06, Vol.11 (6), p.1279-1287

2009

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Functional aspects of membrane association of reggie/flotillin proteins

Current protein & peptide science, 2011-12, Vol.12 (8), p.725-735

2011

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Succinic Semialdehyde Dehydrogenase Deficiency: An Update

Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.477

2020

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Flotillins directly interact with γ-catenin and regulate epithelial cell-cell adhesion

PloS one, 2013-12, Vol.8 (12), p.e84393-e84393

2013

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The Finnish genetic heritage in 2022 – from diagnosis to translational research

Disease models & mechanisms, 2022-10, Vol.15 (10)

2022

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Succinic Semialdehyde Dehydrogenase Deficiency: In Vitro and In Silico Characterization of a Novel Pathogenic Missense Variant and Analysis of the Mutational Spectrum of ALDH5A1

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8578

2020

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Molecular networks in FGF signaling: flotillin-1 and cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2

PloS one, 2012-01, Vol.7 (1), p.e29739-e29739

2012

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Role of EGF-induced tyrosine phosphorylation of reggie-1/flotillin-2 in cell spreading and signaling to the actin cytoskeleton

Journal of cell science, 2007-02, Vol.120 (3), p.395-406

2007

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Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration

Science signaling, 2014-08, Vol.7 (337), p.ra73

2014

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SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player

Frontiers in immunology, 2019-04, Vol.10, p.664-664

2019

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Statistical Permutation Test Reveals Progressive and Region-Specific Iron Accumulation in the Thalami of Children with Aspartylglucosaminuria

Brain sciences, 2020-10, Vol.10 (10), p.1

2020

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A Journey towards Understanding the Molecular Pathology and Developing Therapies for Lysosomal Storage Disorders

Validation of Aspartylglucosaminidase Activity Assay for Human Serum Samples: Establishment of a Biomarker for Diagnostics and Clinical Studies

Endocytic trafficking of membrane-bound cargo: a flotillin point of view

Mitogen-Activated Protein Kinases: Functions in Signal Transduction and Human Diseases

Dissecting the molecular function of reggie/flotillin proteins

Flotillin-1/Reggie-2 Protein Plays Dual Role in Activation of Receptor-tyrosine Kinase/Mitogen-activated Protein Kinase Signaling

Towards Splicing Therapy for Lysosomal Storage Disorders: Methylxanthines and Luteolin Ameliorate Splicing Defects in Aspartylglucosaminuria and Classic Late Infantile Neuronal Ceroid Lipofuscinosis

Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount

Human Desmocollin 3‒Specific IgG Antibodies Are Pathogenic in a Humanized HLA Class II Transgenic Mouse Model of Pemphigus

Dsg3 epitope-specific signalling in pemphigus

Editorial: Pharmacology of gangliosides

Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris

Random Splicing of Several Exons Caused by a Single Base Change in the Target Exon of CRISPR/Cas9 Mediated Gene Knockout

Regulation of ubiquitin-binding proteins by monoubiquitination

Identification of structural elements in Nox1 and Nox4 controlling localization and activity

Functional aspects of membrane association of reggie/flotillin proteins

Succinic Semialdehyde Dehydrogenase Deficiency: An Update

Flotillins directly interact with γ-catenin and regulate epithelial cell-cell adhesion

The Finnish genetic heritage in 2022 – from diagnosis to translational research

Succinic Semialdehyde Dehydrogenase Deficiency: In Vitro and In Silico Characterization of a Novel Pathogenic Missense Variant and Analysis of the Mutational Spectrum of ALDH5A1

Molecular networks in FGF signaling: flotillin-1 and cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2

Role of EGF-induced tyrosine phosphorylation of reggie-1/flotillin-2 in cell spreading and signaling to the actin cytoskeleton

Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration

SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player

Statistical Permutation Test Reveals Progressive and Region-Specific Iron Accumulation in the Thalami of Children with Aspartylglucosaminuria

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